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  1. 221
    “…Surprisingly, COX7A knockdown specifically targeted to DA neurons did not produce locomotor defect. …”
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    Effects on Dopaminergic Neurons Are Secondary in COX-Deficient Locomotor Dysfunction in Drosophila
  2. 222
    “…Selective COX-2 inhibitors have the advantage of reduced side-effects, which result from COX-1 inhibition that is usually observed with nonselective COX inhibitors. …”
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    Crystallography, Molecular Modeling, and COX-2 Inhibition Studies on Indolizine Derivatives
  3. 223
    “…To determine the role of COX-2 in melanoma we developed two melanoma cell lines with stable integration of an inducible doxycycline-regulated expression vector containing a COX-2 targeted micro-RNA (miRNA). …”
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    COX-2 Silencing in Canine Malignant Melanoma Inhibits Malignant Behaviour
  4. 224
    “…The doubly stochastic mechanism generating the realizations of spatial log-Gaussian Cox processes is empirically assessed in terms of generalized entropy, divergence and complexity measures. …”
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    Structural Complexity and Informational Transfer in Spatial Log-Gaussian Cox Processes
  5. 225
    “…Compounds 1 and 2 exhibited strong inhibitory activities against COX-1 and COX-2. Molecular docking analysis of 1 conferred favorable binding against COX-2. …”
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    COX Inhibitory and Cytotoxic Naphthoketal-Bearing Polyketides from Sparticola junci
  6. 226
    “…Therefore, it is of interest to document the molecular docking analysis of compounds from Piper longum with COX-2 using the Autodock Vina PyRx tool. Molecular docking results show that asarinine, sesamine, fargesin, and piperlonguminine have optimal binding energy of 10, 10, -9.5 and 9.4 Kcal/mol, respectively for further consideration.…”
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    Molecular docking analysis of COX-2 with compounds from Piper longum
  7. 227
    “…The biotechnology of knocking down COX-2 and its inhibitor were used on human HCC cell line SMMC7721, and the outcomes confirmed the above results. …”
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    Fluorescence imaging of hepatocellular carcinoma with a specific probe of COX-2
  8. 228
    “…Cytochrome c oxidase subunit VIc (COX6c) is one of the most important subunits of the terminal enzyme of the respiratory chain in mitochondria. …”
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    Novel role of COX6c in the regulation of oxidative phosphorylation and diseases
  9. 229
    “…BACKGROUND: COX4I1 (Cytochrome C oxidase, subunit 4, isoform 1) is a mitochondrial enzyme involved in the process of switching from glycolysis to oxidative phosphorylation. …”
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    BSCI-21 COX4I1 EXPRESSION IN BRAIN METASTASES
  10. 230
    “…Robenacoxib inhibits the cyclooxygenase (COX)‐2 isoform of COX selectively (in vitro IC(50) ratios COX‐1:COX‐2, 129:1 in dogs, 32:1 in cats). …”
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    Pharmacology, safety, efficacy and clinical uses of the COX‐2 inhibitor robenacoxib
  11. 231
    por Cox, Hayward S.
    Publicado 1976
    Libro
    Citotecnologia medica /
  12. 232
    por Wollheim, Frank A
    Publicado 1999
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    New functions for Cox-2 in health and disease: Report of "The Third International Workshop on Cox-2", Ka'upulehu, Kona, Hawaii, USA, 30 August to 2 September 1999
  13. 233
    “…To generate more information, we aimed to evaluate the association of four common polymorphisms (rs3842787, rs20417, rs201184269, rs1126643) from four candidate genes (COX-1, COX-2, ITGA2B, ITGA2) with aspirin insensitivity via a meta-analysis. …”
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    The Association of Four Common Polymorphisms from Four Candidate Genes (COX-1, COX-2, ITGA2B, ITGA2) with Aspirin Insensitivity: A Meta-Analysis
  14. 234
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    Antipyretic activity of Caesalpinia digyna (Rottl.) leaves extract along with phytoconstituent’s binding affinity to COX-1, COX-2, and mPGES-1 receptors: In vivo and in silico approaches
  15. 235
    “…Furthermore, the lead compound responsible for inhibition in the denaturation of proteins is thymol, which exhibits the highest binding affinity with COX1 (−6.4 KJ/mol) and COX2 (−6.3 KJ/mol) inflammatory proteins. …”
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    HPLC, FTIR and GC-MS Analyses of Thymus vulgaris Phytochemicals Executing In Vitro and In Vivo Biological Activities and Effects on COX-1, COX-2 and Gastric Cancer Genes Computationally
  16. 236
    “…The total binding energy of the asiatic acid–COX-2 complex is −7.371 kcal/mol. The anti-inflammatory activity of the asiatic acid inhibition of COX-2 was detected at IC(50) values of 120.17 µM. …”
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    Stability Analysis of the Asiatic Acid-COX-2 Complex Using 100 ns Molecular Dynamic Simulations and Its Selectivity against COX-2 as a Potential Anti-Inflammatory Candidate
  17. 237
    “…Both drugs caused a significant decrease in COX-1 and COX-2 serum level. COX-1 and COX-2 expression in epidermal and dermal inflammatory infiltration did not change significantly in either study group, but a significant decrease of COX-1 expression was observed when the groups were combined for analysis, and the decrease in COX-2 expression in the epidermis was of borderline significance. …”
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    The effect of levocetirizine and montelukast on clinical symptoms, serum level and skin expression of COX-1 and COX-2 enzymes in patients suffering from chronic autoimmune urticaria – a pilot study
  18. 238
    Publicado 2009
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    Brian Cox Large Hadron Collider is all about understanding the forces of nature
  19. 239
    “…CONCLUSION: NETs can promote gastric cancer metastasis by initiating COX-2 through TLR2, and COX-2 may become a target for gastric cancer immunotherapy.…”
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    Effect of NETs/COX-2 pathway on immune microenvironment and metastasis in gastric cancer
  20. 240
    “…BACKGROUND: To compare the ability of the Cox regression and machine learning algorithms to predict the survival of patients with Anaplastic thyroid carcinoma (ATC). …”
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    Comparison of the cox regression to machine learning in predicting the survival of anaplastic thyroid carcinoma
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