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Mostrando 281 - 300 Resultados de 89,050 Para Buscar '"Cox"', tiempo de consulta: 0.57s Limitar resultados
  1. 281
    “…The histological studies showed that groups with the tumor showed a statistically significant higher presence of Cox-2 compared to the control. In the Cox-2 analysis of the abdominal wall, the ascites group showed the most significant difference. …”
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    GROWTH FACTORS AND COX2 IN WOUND HEALING: AN EXPERIMENTAL STUDY WITH EHRLICH TUMORS
  2. 282
    “…The aim of the present study was to identify the role of cyclooxygenase-2 (COX-2) in Smad3 mutant mice, which are known to develop colon cancer. …”
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    Smad3 mutant mice develop colon cancer with overexpression of COX-2
  3. 283
    “…We adapted survival analysis using the Cox regression model with 2011 Ethiopian Demographic and Health Survey data. …”
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    Survival analysis of under-five mortality using Cox and frailty models in Ethiopia
  4. 284
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    Beyond COX-1: the effects of aspirin on platelet biology and potential mechanisms of chemoprevention
  5. 285
    “…Then, pharmacological tools (MK801, a NMDA receptor inhibitor; Dickkopf homolog 1, a specific inhibitor of the Wnt pathway; NS-398, a COX-2 inhibitor; and bevacizumab, IVB, a VEGF inhibitor) were introduced to evaluate the detailed roles of Wnt/β-catenin, COX-2, and VEGF in retinopathy of rats. …”
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    The Involvement of β-Catenin/COX-2/VEGF Axis in NMDA-Caused Retinopathy
  6. 286
    “…A549 cells were transfected and grouped as follows: blank group, siRNA-negative control group, siRNA-COX-2 group and resveratrol + siRNA-COX-2 group. qRT-PCR and Western blot were conducted to detect COX-2 expression. …”
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    Resveratrol inhibits the proliferation of A549 cells by inhibiting the expression of COX-2
  7. 287
    “…BACKGROUND: An (18)F-tagged NSAID analog was prepared for use as a probe for COX-2 expression, which is associated with tumor development. …”
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    Synthesis and evaluation of ortho-[(18)F] fluorocelecoxib for COX-2 cholangiocarcinoma imaging
  8. 288
    “…However, COX inhibition using NSAIDs exacerbate IBD and thus is not a viable solution. …”
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    Resolution of Cox mediated inflammation by Se supplementation in mouse experimental model of colitis
  9. 289
    por Nagashima, Kengo, Sato, Yasunori
    Publicado 2017
    “…In the estimation of Cox regression models, maximum partial likelihood estimates might be infinite in a monotone likelihood setting, where partial likelihood converges to a finite value and parameter estimates converge to infinite values. …”
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    Information criteria for Firth's penalized partial likelihood approach in Cox regression models
  10. 290
    “…The in vitro COX inhibition assays were performed against ovine COX-1 and human recombinant COX-2. …”
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    COX Inhibition Profile and Molecular Docking Studies of Some 2-(Trimethoxyphenyl)-Thiazoles
  11. 291
    “…Targeted disruption of PKCε from prostate cancer cells impaired COX-2 induction and PGE(2) production. Notably, COX-2 inhibitors selectively killed prostate epithelial cells overexpressing PKCε, and this ability was greatly enhanced by Pten loss. …”
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    COX-2 MEDIATES PRO-TUMORIGENIC EFFECTS OF PKCε IN PROSTATE CANCER
  12. 292
    “…COX20/FAM36A encodes a mitochondrial complex IV assembly factor important for COX2 activation. …”
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    Novel pathogenic COX20 variants causing dysarthria, ataxia, and sensory neuropathy
  13. 293
    “…[Image: see text] In vivo targeting and visualization of cyclooxygenase-1 (COX-1) using multimodal positron emission tomography/computed tomography imaging represents a unique opportunity for early detection and/or therapeutic evaluation of ovarian cancer because overexpression of COX-1 has been characterized as a pathologic hallmark of the initiation and progression of this disease. …”
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    Discovery of Furanone-Based Radiopharmaceuticals for Diagnostic Targeting of COX-1 in Ovarian Cancer
  14. 294
    “…However, the efficacy of such therapy involving COX-2 inhibition depends on various factors viz., therapeutic dose, time of administration, treatment duration, and selectivity of COX-2 inhibitors. …”
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    Cyclooxygenase-2 (COX-2) inhibitors: future therapeutic strategies for epilepsy management
  15. 295
    por Cheng, Mi Hyun, Kim, Sung-Jin
    Publicado 2020
    “…Western blot analysis indicated that probenecid affects two downstream signaling molecules of ROS, cyclooxygenase 2 (COX-2) and c-Jun N-terminal kinase (JNK). These results indicate that probenecid inhibits ROS generation and exerts antiosteoclastogenic activity by inhibiting the COX-2 and JNK pathways. …”
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    Inhibitory Effect of Probenecid on Osteoclast Formation via JNK, ROS and COX-2
  16. 296
    “…All compounds were evaluated for their inhibition against cyclooxyenase-2 (COX-2), in which compound 4 showed significant inhibitory effect against COX-2 with IC(50) value of 3.98 ± 0.32 μM, comparable to that of positive control NS-398 (IC(50) 4.14 ± 0.28 μM). …”
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    Triterpenoids from Ainsliaea latifolia and Their Cyclooxyenase-2 (COX-2) Inhibitory Activities
  17. 297
    “…In order to assess the role of COX-2 in colitis-induced carcinogenesis, the selective COX-2 inhibitor celecoxib and COX-2 null mice were exploited in an azoxymethane (AOM)-initiated and dextran sulfate sodium (DSS)-promoted murine colon carcinogenesis model. …”
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    Effects of Genetic and Pharmacologic Inhibition of COX-2 on Colitis-associated Carcinogenesis in Mice
  18. 298
    por Omae, Katsuhiro, Eguchi, Shinto
    Publicado 2020
    “…This provides a natural extension of Cox model that leads to a mixture hazards model. …”
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    Quasi-linear Cox proportional hazards model with cross- L(1) penalty
  19. 299
    “…Among these, multimodal analgesic regimens stand out as a promising treatment options. Cyclo-oxygenase (COX) inhibitor/opioid receptor agonist combinations hold great potential as effective pillars in the multimodal pain management by providing adequate analgesia with fewer safety risks due to COX inhibitors’ opioid-sparing effect. …”
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    The Expanding Role of the COX Inhibitor/Opioid Receptor Agonist Combination in the Management of Pain
  20. 300
    “…CONCLUSION: These data demonstrate that inhibition of mPGES-1 spares the renal COX-2/ADMA pathway and define mechanistically how COX-2 regulates ADMA.…”
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    Mechanistic definition of the cardiovascular mPGES-1/COX-2/ADMA axis
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