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341por Wang, Ding-Ran“…The Kaplan-Meier curve analysis and log-rank test were performed to determine the possible factors influencing the 5-year cumulative survival rate in the patients. The Cox regression analysis was performed to identify the factors influencing the survival prognosis of endometrial cancer. …”
Publicado 2023
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342por Mohanty, Soumitra, Lindelauf, Ciska, White, John Kerr, Scheffschick, Andrea, Ehrenborg, Ewa, Demirel, Isak, Brauner, Hanna, Brauner, Annelie“…BACKGROUND: To avoid the overuse of antibiotics, non-steroidal anti-inflammatory drugs (NSAIDs), acting via cyclooxygenase (COX) inhibition, have been used to reduce pain and as an alternative treatment for uncomplicated urinary tract infections (UTIs). …”
Publicado 2023
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343por Zhang, Shuaijie, Yang, Fan, Wang, Lijie, Si, Shucheng, Zhang, Jianmei, Xue, Fuzhong“…MTL-Cox employs a multitask learning framework to train semiparametric multivariable Cox models. …”
Publicado 2023
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344por Guhathakurta, Sukanya, Erdogdu, Niyazi Umut, Hoffmann, Juliane J., Grzadzielewska, Iga, Schendzielorz, Alexander, Seyfferth, Janine, Mårtensson, Christoph U., Corrado, Mauro, Karoutas, Adam, Warscheid, Bettina, Pfanner, Nikolaus, Becker, Thomas, Akhtar, Asifa“…Loss of COX17 or expression of its non-acetylatable mutant phenocopies the mitochondrial defects observed upon MOF depletion. …”
Publicado 2023
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345“…The presence of glutathione used at a physiological concentration and redox potential was sufficient to support the oxidation of COX19 by AtERV1, providing a likely explanation for why MIA40 is not essential for the import and oxidative folding of IMS-located proteins in Arabidopsis. …”
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346por Sierra-López, Francisco, Castelan-Ramírez, Ismael, Hernández-Martínez, Dolores, Salazar-Villatoro, Lizbeth, Segura-Cobos, David, Flores-Maldonado, Catalina, Hernández-Ramírez, Verónica Ivonne, Villamar-Duque, Tomás Ernesto, Méndez-Cruz, Adolfo René, Talamás-Rohana, Patricia, Omaña-Molina, Maritza“…In addition, some EVs biological characteristics were determined, such as proteolytic, hemolytic and COX activity. Furthermore, we highlighted the presence of leishmanolysin in trophozites and EVs. …”
Publicado 2023
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347por Nieminen, Riina, Leinonen, Sari, Lahti, Aleksi, Vuolteenaho, Katriina, Jalonen, Ulla, Kankaanranta, Hannu, B. Goldring, Mary, Moilanen, Eeva“…Inducible prostaglandin synthase (cyclooxygenase-2, COX-2) is expressed in rheumatoid and osteoarthritic cartilage and produces high amounts of proinflammatory prostanoids in the joint. …”
Publicado 2005
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348“…BACKGROUND: Epidemiologic and laboratory investigations suggest that nonsteroidal anti-inflammatory drugs (NSAIDs) have chemopreventive effects against breast cancer due to their activity against cyclooxygenase-2 (COX-2), the rate-limiting enzyme of the prostaglandin cascade. …”
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349“…This nonlinear isobologram model for binary mixtures can be expressed as [formula: see text] In addition, a Box-Cox transformation to both sides is introduced to improve the goodness of fit and to provide a more robust model for achieving homogeneity and normality of the residuals. …”
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350por Zhang, Xiao-Hua, Huang, Du-Ping, Guo, Gui-Long, Chen, Guo-Rong, Zhang, Hu-Xiang, Wan, Li, Chen, Sheng-Ying“…However, possible role of COX-2 in lymphangiogenesis and lymphatic metastasis is still poorly understood. …”
Publicado 2008
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351“…Increased expression of COX-2 or VEGF-C has been correlated with progressive disease in certain cancers. …”
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352“…In this study, the EGF-induced increase of CEBPB mRNA is shown to be coincident with the decrease of COX-2 mRNA. We identified that all of the individual CEBPB isoforms, LAP1, LAP2 and LIP, attenuate EGF-induced COX-2 promoter activity. …”
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353“…Evidence suggests that COX-2 contributes to UV-induced carcinogenesis. …”
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356por Ishiura, Yoshihisa, Fujimura, Masaki, Yamamoto, Hiroki, Ohkura, Noriyuki, Myou, Shigeharu“…Accumulating evidences indicate that cyclooxygenase (COX)-2, one of the inducible isoforms of COX, is a key element in the pathophysiological process of a number of inflammatory disorders. …”
Publicado 2010
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357“…The two major limitations of Golgi–Cox method are that staining takes very long time and it is inconsistent. …”
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358por Gou, Hong-Feng, Chen, Xin-Chuan, Zhu, Jiang, Jiang, Ming, Yang, Yu, Cao, Dan, Hou, Mei“…However, the impact of COX-2 on lymphangiogenesis of gastric cancer remains unclear. …”
Publicado 2011
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359“…Overall 4-year survival after initial relapse was 34.2% and there was no significant difference in survival between those who relapsed during maintenance therapy and those who relapsed after completing maintenance. The Cox proportional hazards model identified central nervous system (CNS) irradiation (P < 0.001) as having the most important influence upon EFS, followed by serum alanine aminotransferase level, platelet level, and age. …”
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360por Subramaniya, Bharathi Raja, Srinivasan, Gayathri, Mohammed Sadullah, Sakeena Sadullah, Davis, Nimitha, Baddi Reddi Subhadara, Lakshmi, Halagowder, Devaraj, Sivasitambaram, Niranjali Devaraj“…Hence the observed resistance to induction of apoptosis in 50 µM plumbagin treated HT29 cells are attributed to the expression of COX-2. In conclusion, plumbagin induces apoptosis in colonic cancer cells through TNF-α mediated pathway depending on expression of COX-2 expression.…”
Publicado 2011
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