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Mostrando 401 - 420 Resultados de 89,050 Para Buscar '"Cox"', tiempo de consulta: 0.53s Limitar resultados
  1. 401
    “…The present study aimed to demonstrate the role of miR-101 and cyclooxygenase-2 (COX-2) in the initiation and development of glioma. …”
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    miR-101 inhibits glioma cell invasion via the downregulation of COX-2
  2. 402
    “…This study proposes the molecular basis for the dual FAAH/COX inhibition by this novel hybrid scaffold, stimulating further experimental studies and offering new insights for the rational design of novel anti‐inflammatory agents that simultaneously act on FAAH and COX.…”
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    The Molecular Basis for Dual Fatty Acid Amide Hydrolase (FAAH)/Cyclooxygenase (COX) Inhibition
  3. 403
    “…COX2, one of the isoforms of COX, is highly inducible in response to a wide variety of cellular and environmental stresses. …”
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    Transgenic expression of cyclooxygenase-2 (COX2) causes premature aging phenotypes in mice
  4. 404
    por Szafranski, Przemyslaw
    Publicado 2017
    “…In Campsomeris mtDNA, cox2a and cox2b loci are separated by a 3-kb large cluster of several antiparallel overlapping ORFs, one of which, qnu, seems to encode a nuclease that may have played a role in cox2 fission. …”
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    Evolutionarily recent, insertional fission of mitochondrial cox2 into complementary genes in bilaterian Metazoa
  5. 405
    “…According to 3D modelling CoxVIIIa and CoxVIIc are buried in the CI(1)CIII(2)CIV(1) supercomplex. …”
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    Lifetime imaging of GFP at CoxVIIIa reports respiratory supercomplex assembly in live cells
  6. 406
    “…New radiochemistry techniques can yield novel PET tracers for COX-2 and address the shortcomings in in vivo stability and specificity, which have held back clinical translation of tracers to image COX-2 expression. …”
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    Radiochemistry on electrodes: Synthesis of an (18)F-labelled and in vivo stable COX-2 inhibitor
  7. 407
    “…The current study focused on the expression levels of nm23-H1 and COX-2 in 130 human thyroid papillary carcinoma (PTC) tissues. …”
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    Expression of nm23-H1 and COX-2 in thyroid papillary carcinoma and microcarcinoma
  8. 408
    por Han, Jeong A., Kim, Jong-Il
    Publicado 2017
    “…In contrast, celecoxib, another COX-2–selective inhibitor, and aspirin, a non-selective COX inhibitor, accelerated the senescence and aging. …”
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    Analysis of Gene Expression in Human Dermal Fibroblasts Treated with Senescence-Modulating COX Inhibitors
  9. 409
    “…To obtain a full understanding of the genetic diversity of the cytochrome oxidase III gene (COX-III) and its association with high altitude adaptation in Tibetan chickens, we sequenced COX-III in 12 chicken populations (155 Tibetan chickens and 145 other domestic chickens). …”
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    A Comparison of Genetic Diversity of COX-III Gene in Lowland Chickens and Tibetan Chickens
  10. 410
    “…The expressions of MMP-7, TIMP-1 and COX-2 were investigated by real time-polymerase chain reaction (RT-PCR). …”
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    Expressions of TIMP-1, COX-2 and MMP-7 in Colon Polyp and Colon Cancer
  11. 411
    “…Recent studies demonstrate that the melanoma metastasis has correlations with the heightened activations of protein kinase C ζ (PKCζ) and cyclooxygenase-2 (COX-2) signaling pathways. Targeted inhibitions for PKCζ and COX-2 have been considered as the promising strategies for the treatment of melanoma metastasis. …”
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    Combination therapy of PKCζ and COX-2 inhibitors synergistically suppress melanoma metastasis
  12. 412
    por Hu, Tieyi, Xi, Jiazhuang
    Publicado 2017
    “…Furthermore, statistical analysis showed the COX5B expression level was significantly associated with clinical stage and lymph node status, while there were no correlations between COX5B expression and age or tumor size. …”
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    Identification of COX5B as a novel biomarker in high-grade glioma patients
  13. 413
    “…Because of its biocompatibility, this degradable dextran delivered COX-2 siRNA within tumors and efficiently downregulated COX-2 expression.…”
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    Acid-degradable Dextran as an Image Guided siRNA Carrier for COX-2 Downregulation
  14. 414
    “…Therefore, COX-2, which acts on abnormal tumor vessels, is expected to become a novel target for tumor treatment.…”
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    COX-2 inhibition in the endothelium induces glucose metabolism normalization and impairs tumor progression
  15. 415
    “…Chemoprevention with selective COX-2 inhibitors may be helpful to repress the development of skin cancers derived from DNA-damaged KCs.…”
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    Voriconazole-induced photocarcinogenesis is promoted by aryl hydrocarbon receptor-dependent COX-2 upregulation
  16. 416
    por Tian, Suyan
    Publicado 2018
    “…In the present study, the Cox filter model, a feature selection algorithm that identifies subtype-specific prognostic genes to incorporate pathway information and eliminate redundant genes, was adopted. …”
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    Identification of subtype-specific prognostic signatures using Cox models with redundant gene elimination
  17. 417
    “…IL-33 activated cycloxygenase-2 (COX2) expression and increased PGE(2) production, whereas the COX2 selective inhibitor and PGE(2) neutralizing antibody abolished the proliferation promoting effect of IL-33. …”
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    IL-33 facilitates proliferation of colorectal cancer dependent on COX2/PGE(2)
  18. 418
    “…Previous studies demonstrated the importance of upregulation of inflammatory factors, such as cyclooxygenase 2 (cox2), in tumor tolerance. In the present study, we investigated the role of cox2 in radiosensitivity of lung cancer. …”
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    Disruption of Chromosomal Architecture of cox2 Locus Sensitizes Lung Cancer Cells to Radiotherapy
  19. 419
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    Role of COX-2/PGE2 Mediated Inflammation in Oral Squamous Cell Carcinoma
  20. 420
    “…Ingested flavonoids have been reported to directly affect the regulation of cyclooxygenase-2 (COX-2) expression induced by bacterial toxins. In this study, we examined the effects of four flavonoids (luteolin, fisetin, morin and myricetin) on the activation of ERK1/2, p38 and AKT, and on the synthesis of COX-2 in human gingival fibroblasts treated with LTA from Streptococcus sanguinis. …”
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    Myricetin blocks lipoteichoic acid-induced COX-2 expression in human gingival fibroblasts
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