“…This is dependent on the inflammatory senescence-associated secretory phenotype (SASP), which includes COX2, an enzyme with complex roles in cancer. The role COX2 plays during senescence surveillance is unknown. …”
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“…BACKGROUND: The Cox proportional hazards model is commonly used to predict hazard ratio, which is the risk or probability of occurrence of an event of interest. …”
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“…The Cox-Merz rule is an empirical relationship that is commonly used in science and industry to determine shear viscosity on the basis of an oscillatory rheometry test. …”
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“…Hundreds of thousands have been forced out of the country, with a large proportion settling in refugee camps in Cox’s Bazar, Bangladesh. This study examines the impacts of exposure to trauma on mental health outcomes among Rohingya adolescents living in Bangladesh. …”
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“…This research provides a clear guideline for a valid survival analysis using the Cox proportional hazard model with machine learning-based imputations.…”
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“…BACKGROUND: Previous study has been reported that COX4I2 expression level demonstrated a positive correlation with microvessel density in pheochromocytomas (PCC) samples, suggesting that the expression of COX4I2 maybe related to blood supply level in other adrenal tumors as well. …”
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“…COX-2 inhibitors block COX activity without affecting POX activity. …”
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“…The inhibitory potential of the fractions and extracts against the COX-2 enzyme was determined using a fluorometric COX-2 inhibition assay. …”
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“…Here we investigate the involvement of the COX complex assembly chaperone COX11 (cytochrome c oxidase 11) in cellular redox homeostasis, using homologs from the flowering plant Arabidopsis thaliana (AtCOX11) and yeast Saccharomyces cerevisiae (ScCOX11). …”
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“…For most researchers, discovering new anticancer drugs to avoid the adverse effects of current ones, to improve therapeutic benefits and to reduce resistance is essential. Because the COX-2 enzyme plays an important role in various types of cancer leading to malignancy enhancement, inhibition of apoptosis, and tumor-cell metastasis, an indispensable objective is to design new scaffolds or drugs that possess combined action or dual effect, such as kinase and COX-2 inhibition. …”
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“…Overall, it can be concluded that yield of G. tenuistipitata in coast of Cox’s Bazar could be improved considering those factors.…”
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“…The role of activation of the COX-2/PGE(2) pathway in dedifferentiation of cardiac myofibroblasts remains unknown. …”
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“…PURPOSE: Cyclooxygenase (COX-2) has been validated as a molecular target for treating inflammatory diseases. …”
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“…OBJECTIVE: Several studies were conducted to explore the clinical significance of cyclooxygenase-2 (COX-2) overexpression in laryngeal cancer. However, the associations between COX-2 overexpression and clinicopathological characteristics of laryngeal cancer patients remained unclear. …”
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“…In silico simulation and modeling for three COX-2 active—p-fluoro, p-hydroxy and p-amino—fenbufens show a preferable docking to COX-2 than COX-1. …”
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“…This article reviews the evolution of ablation strategies, beginning with the origin of the Cox maze IV procedure and continuing to the recent hybrid convergent approach, and provides a summary of the associated outcomes.…”
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“…We obtained expression profiles from The Cancer Genome Atlas (TCGA) database and constructed a LASSO-Cox regression model to predict the prognosis of AML using multiomics bioinformatic analysis data. …”
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“…The aim of the study was to represent an assessment of the Rohingya people's COVID-19-related knowledge, attitude, and practices (KAP) at eight refugee camps in Cox's Bazar. STUDY DESIGN: Cross-sectional study. …”
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“…COX-2 immunostaining could be a potential prognostic factor for survival in PTC. …”
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