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681por Rocca, Jérémy, Manin, Sylvie, Hulin, Anne, Aissat, Abdel, Verbecq‐Morlot, Wilfried, Prulière‐Escabasse, Virginie, Wohlhuter‐Haddad, Adeline, Epaud, Ralph, Fanen, Pascale, Tarze, AgatheEnlace del recurso
Publicado 2016
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682por Nogueira, Renan Brito, Pires, Andréa Rodrigues Cordovil, Soares, Thélia Maria Santos, Rodrigues, Simone Rabello de Souza, Campos, Mariane Antonieta Menino, Toloi, Giovanna Canato, Waisberg, Jaques“…OBJECTIVE: To analyze the immunoexpression of the COX-2, p53, and caspase-3 proteins in colorectal adenomas and non-neoplastic mucosa. …”
Publicado 2013
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683“…For this, literature reporting on COX inhibitors exerting radioprotective and/or radiosensitizing action as well as on antioxidant COX inhibitors will be reviewed comprehensively with the aim to find cross-points of both and, by that, stimulate further research in the field of radioprotective agents.…”
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684“…Therefore, many studies have been focusing on the molecular pathways involved in DTs in order to develop molecular-targeted therapies or chemotherapy. Cyclooxygenase-2 (COX-2) has been demonstrated to play a role in the growth of DTs, and the pharmacologic blockade of COX resulted in decreased cell proliferation in desmoid cell cultures in vitro. …”
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685por Ueno, Yasuaki, Nakamura, Masanao, Watanabe, Osamu, Yamamura, Takeshi, Funasaka, Kohei, Ohno, Eizaburo, Miyahara, Ryoji, Kawashima, Hiroki, Goto, Hidemi, Hirooka, Yoshiki“…In the tissue sampled by DBE, apoptotic bodies were found; therefore, it was suggested that the stenoses in this case were caused by the COX-2 inhibitor from the relationship between COX-2 inhibition and apoptosis. …”
Publicado 2016
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686por Frykholm, Karolin, Berntsson, Ronnie Per-Arne, Claesson, Magnus, de Battice, Laura, Odegrip, Richard, Stenmark, Pål, Westerlund, Fredrik“…We here use fluorescence microscopy to study single DNA–Cox complexes in nanofluidic channels and compare how the Cox homologs from phages P2 and WΦ affect DNA. …”
Publicado 2016
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687“…Given that inflammation is increasingly being associated with neurodegenerative and psychiatric processes, we sought to elucidate mechanisms by which E2 down-regulates a component of an inflammatory response, cyclooxygenase– 2 (COX-2) expression. Although inflammatory processes in the brain are usually associated with microglia and astrocytes, we found that the COX-2 gene (cox-2) was expressed in a neuronal context, specifically in an amygdalar cell line (AR-5). …”
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688por Hang, Junjie, Hu, Hai, Huang, Junjie, Han, Ting, Zhuo, Meng, Zhou, Yangyang, Wang, Lei, Wang, Yi, Jiao, Feng, Wang, Liwei“…In this study, we investigated the prognostic value of Sp1 and COX2 in 88 PDAC patients. Our study showed there was a positive correlation between Sp1 and COX2 expression (P=0.001) by using the Spearman's rank test. …”
Publicado 2016
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689por Tonby, Kristian, Wergeland, Ida, Lieske, Nora V., Kvale, Dag, Tasken, Kjetil, Dyrhol-Riise, Anne M.“…Upregulated cyclooxygenase-2 (COX-2)-prostaglandin E2 (PGE2) signaling pathway may cause a dysfunctional immune response that favors survival and replication of Mycobacterium tuberculosis (Mtb). …”
Publicado 2016
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690por Lorenzi, Isotta, Oeljeklaus, Silke, Ronsör, Christin, Bareth, Bettina, Warscheid, Bettina, Rehling, Peter, Dennerlein, Sven“…The Mba1-Cox20 complex accumulates when export of the C terminus of Cox2 is blocked by the loss of the Cox18 protein. …”
Publicado 2016
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691por Farrell, Jordan S, Gaxiola-Valdez, Ismael, Wolff, Marshal D, David, Laurence S, Dika, Haruna I, Geeraert, Bryce L, Rachel Wang, X, Singh, Shaily, Spanswick, Simon C, Dunn, Jeff F, Antle, Michael C, Federico, Paolo, Teskey, G CampbellEnlace del recurso
Publicado 2016
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692por Alfajaro, Mia Madel, Choi, Jong-Soon, Kim, Deok-Song, Seo, Ja-Young, Kim, Ji-Yun, Park, Jun-Gyu, Soliman, Mahmoud, Baek, Yeong-Bin, Cho, Eun-Hyo, Kwon, Joseph, Kwon, Hyung-Jun, Park, Su-Jin, Lee, Woo Song, Kang, Mun-Il, Hosmillo, Myra, Goodfellow, Ian, Cho, Kyoung-Oh“…Here, using only cultivable porcine sapovirus (PSaV) strain Cowden, we demonstrate that PSaV induced the vitalization of the cyclooxygenase (COX) and prostaglandin E(2) (PGE(2)) pathway. Targeting of COX-1/2 using nonsteroidal anti-inflammatory drugs (NSAIDs) such as the COX-1/2 inhibitor indomethacin and the COX-2-specific inhibitors NS-398 and celecoxib or siRNAs targeting COXs, inhibited PSaV replication. …”
Publicado 2017
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693“…We carried out five separate Cox analyses and the two-modality neuroimaging Cox model identified three significant network-based risk factors with higher prediction performance (accuracy = 73.50%) than those in either single-modality model (accuracy = 68.80%). …”
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694“…We developed COX-2 knockdown stable clones from DiFi5 cells and demonstrated that genetic knockdown of COX-2 partially re-sensitized DiFi5 cells to cetuximab. …”
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695Polymorphisms of the murine mitochondrial ND4, CYTB and COX3 genes impact hematopoiesis during agingpor Kretzschmar, Christin, Roolf, Catrin, Timmer, Katrin, Sekora, Anett, Knübel, Gudrun, Escobar, Hugo Murua, Fuellen, Georg, Ibrahim, Saleh M., Tiedge, Markus, Baltrusch, Simone, Jaster, Robert, Köhling, Rüdiger, Junghanss, Christian“…Herein, three mouse strains with mtDNA polymorphisms in genes of respiratory chain complexes I (ND4), III (CYTB) and IV (COX3) were compared to a reference strain during aging. …”
Publicado 2016
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696por Okuda-Tanino, Asa, Sugawara, Daiki, Tashiro, Takumi, Iwashita, Masaya, Obara, Yutaro, Moriya, Takahiro, Tsushima, Chisato, Saigusa, Daisuke, Tomioka, Yoshihisa, Ishii, Kuniaki, Nakahata, Norimichi“…Because licochalcone A also inhibited arachidonic acid-induced platelet aggregation and production of thromboxane A(2) induced by collagen in intact platelets, we further examined the direct interaction of licochalcone A with cyclooxygenase (COX)-1. As expected, licochalcone A caused an inhibitory effect on both COX-1 and COX-2 in vitro. …”
Publicado 2017
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697por Tang, Shi-Hang, Gao, Jin-Hang, Wen, Shi-Lei, Tong, Huan, Yan, Zhao-Ping, Liu, Rui, Tang, Cheng-Wei“…In the present study, the correlations between lncRNA-COX-2 RNA expression levels, COX-2 mRNA expression levels and liver fibrosis were examined. …”
Publicado 2017
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698por Liang, Xing, Yang, Li-Xia, Guo, Ruiwei, Shi, Yankun, Hou, Xianhua, Yang, Zhihua, Zhou, Xiaobin, Liu, Hong“…In vitro, oxidized low-density lipoprotein (ox-LDL) induced the expression of cyclooxygenase-2 (COX-2) and EMMPRIN in THP-1 macrophages, and atorvastatin inhibited ox-LDL-induced expression of PGE2, EMMPRIN and COX-2 in THP-1 macrophages. …”
Publicado 2017
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699“…We also compared brain-coX’s performance to that of its main competitors, Endeavour and ToppGene, focusing on the ability to discover novel associations. …”
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700por Gomes, Gustavo Gir, Gali, Wagner Luis, Sarabanda, Alvaro Valentim Lima, da Cunha, Claudio Ribeiro, Kessler, Iruena Moraes, Atik, Fernando Antibas“…BACKGROUND: Cox-Maze III procedure is one of the surgical techniques used in the surgical treatment of atrial fibrillation (AF). …”
Publicado 2017
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