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Mostrando 801 - 820 Resultados de 89,050 Para Buscar '"Cox"', tiempo de consulta: 0.75s Limitar resultados
  1. 801
    “…We constructed and compared the “augmented” Cox model (incorporating the two PRS, known and novel predictors) with a “baseline” Cox model (incorporating the two PRS and known predictors) for risk prediction. …”
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    Combining machine learning with Cox models to identify predictors for incident post-menopausal breast cancer in the UK Biobank
  2. 802
    “…We investigate the roles of COX5A in DOX-induced cardiomyopathy and explore the underlying mechanisms. …”
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    COX5A Alleviates Doxorubicin-Induced Cardiotoxicity by Suppressing Oxidative Stress, Mitochondrial Dysfunction and Cardiomyocyte Apoptosis
  3. 803
    “…Here, we found that p23 is a previously unidentified transcription factor of COX-2, and its nuclear localization predicts the poor clinical outcomes. …”
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    The p23 co-chaperone is a succinate-activated COX-2 transcription factor in lung adenocarcinoma tumorigenesis
  4. 804
    “…Inhibition of cyclooxygenase-2 (COX-2) has been extensively studied as an approach to reduce proinflammatory markers in acute brain diseases, but the anti-neuroinflammatory role of cyclooxygenase-1 (COX-1) inhibition has been rather neglected. …”
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    m-Terphenylamines, Acting as Selective COX-1 Inhibitors, Block Microglia Inflammatory Response and Exert Neuroprotective Activity
  5. 805
    “…OBJECTIVES: To determine from a health plan perspective the cost-effectiveness of cyclooxygenase-2 (COX-2) specific inhibitors, with and without a prior-authorization (PA) process. …”
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    Pharmacoeconomic Modeling of Prior-Authorization Intervention for COX-2 Specific Inhibitors in a 3-Tier Copay Plan
  6. 806
    “…The objective of this study was to examine whether use of COX-2 inhibitors is associated with reduced risk of GI bleed in a managed care population. …”
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    Gastrointestinal Bleeding Rates Among Managed Care Patients Newly Started on COX-2 Inhibitors or Nonselective NSAIDs
  7. 807
    “…A Group II intronic sequence was identified between two exons of the cox1 gene, and this sequence comprises an open reading frame (ORF) that encodes a hypothetical protein. …”
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    Complete Mitogenome Sequencing, Annotation, and Phylogeny of Grateloupia turuturu, a Red Alga with Intronic cox1 Gene
  8. 808
    “…INTRODUCTION: COX-2 is overexpressed in colorectal tumour tissue relative to the healthy colonic mucosa, thus we investigated the prognostic significance of COX-2 in determining the metastasis of patients with colorectal cancer. …”
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    The prognostic value of COX-2 in predicting metastasis of patients with colorectal cancer: A systematic review and meta analysis
  9. 809
    “…To develop a prognostic model, Cox regression analyses were used to assess the relationship between clinic-pathologic factors and disease-free survival (DFS). …”
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    Predicting survival of advanced laryngeal squamous cell carcinoma: comparison of machine learning models and Cox regression models
  10. 810
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    Improving the Robustness of Variable Selection and Predictive Performance of Regularized Generalized Linear Models and Cox Proportional Hazard Models
  11. 811
    “…A prognostic signature was developed via the least absolute shrinkage and selection operator-cox regression method. To evaluate the accuracy of the signature in predicting events, multi-type technical means, such as Kaplan–Meier plots, receiver operating characteristic curve analysis, nomogram construction, and univariate and multivariate Cox regression studies were performed. …”
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    Development of a prognostic signature based on anoikis-related genes in hepatocellular carcinoma with the utilization of LASSO-cox method
  12. 812
    “…This study intended to figure out the bioactive compounds in the two varieties of B. alba (native and hybrid) fruit extract and measurement its biological activities like antioxidant, anti-inflammatory, cytotoxic activities and a molecular docking were performed to observed the pharmaceutical impact on the anti-inflammatory Cyclooxygenase-2 (COX-2) enzyme. The cold extractions along with GC-MS were used for the extraction of and analysis of phytoconstituents from B. alba fruit. …”
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    Determination of biological activities of malabar spinach (Basellaalba) fruit extracts and molecular docking against COX-II enzyme
  13. 813
    “…The genomic environments and the transcripts of the mitochondrial cox3 gene are investigated in three Arabidopsis thaliana ecotypes. …”
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    Distant sequences determine 5′ end formation of cox3 transcripts in Arabidopsis thaliana ecotype C24
  14. 814
    “…Celecoxib, a cyclooxygenase-2 (COX-2) inhibitor, is known to downregulate Bcl-2 expression. …”
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    Adenovirus type 5 E1A-induced apoptosis in COX-2-overexpressing breast cancer cells
  15. 815
    “…BACKGROUND: This paper describes a likelihood approach to model the relation between failure time and haplotypes in studies with unrelated individuals where haplotype phase is unknown, while dealing with the problem of unstable estimates due to rare haplotypes by considering a penalized log-likelihood. RESULTS: The Cox model presented here incorporates the uncertainty related to the unknown phase of multiple heterozygous individuals as weights. …”
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    Estimating effects of rare haplotypes on failure time using a penalized Cox proportional hazards regression model
  16. 816
    “…In conclusion, the IGCC classification in three prognostic groups is largely supported by Cox regression and recursive partitioning. Cox regression was the most promising tool to define a more refined classification.…”
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    Survival of patients with nonseminomatous germ cell cancer: a review of the IGCC classification by Cox regression and recursive partitioning
  17. 817
    “…Inhibition or knockdown of COX-2 was achieved by treating NSCLC cells with specific COX-2 inhibitor NS-398 or COX-2 siRNA, respectively. …”
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    Effects of COX-2 inhibition on expression of vascular endothelial growth factor and interleukin-8 in lung cancer cells
  18. 818
    “…[Image: see text] Ibuprofen and mefenamic acid are weak, competitive inhibitors of cyclooxygenase-2 (COX-2) oxygenation of arachidonic acid (AA) but potent, noncompetitive inhibitors of 2-arachidonoylglycerol (2-AG) oxygenation. …”
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    Differential Sensitivity and Mechanism of Inhibition of COX-2 Oxygenation of Arachidonic Acid and 2-Arachidonoylglycerol by Ibuprofen and Mefenamic Acid
  19. 819
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    Reversal of gene expression changes in the colorectal normal-adenoma pathway by NS398 selective COX2 inhibitor
  20. 820
    “…We hypothesized that the Cox regression model might identify these factors. …”
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    A new method to analyse the pace of child development: Cox regression validated by a bootstrap resampling procedure
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