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87661por Florea, Ana, Sy, Lina S, Qian, Lei, Ackerson, Bradley, Luo, Yi, Wu, Jun, Cheng, Yanjun, Ku, Jennifer H, Vega Daily, Leticia I, Takhar, Harpreet, Song, Jeannie, Chmielewski-Yee, Elizabeth, Spence, O M areen, Seifert, Harry, Oraichi, Driss, Tseng, Hung Fu“…The index date for vaccinated individuals was the date of the second dose; unvaccinated individuals had the same index date as their vaccinated match. Cox proportional hazards models were used to estimate adjusted hazard ratios (aHRs) with 95% confidence intervals (CIs) comparing outcomes (HZ and PHN) in the vaccinated and unvaccinated groups. …”
Publicado 2023
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87662por Cardemil, Cristina, Munoz, Flor M, Cao, Yi, Gao, Fei, Posavad, Christine M, Badell, Martina L, Bunge, Katherine E, Mulligan, Mark J, Parameswaran, Lalitha, Olson-Chen, Courtney, Novak, Richard M, Brady, Rebecca C, DeFranco, Emily A, Gerber, Jeffrey S, Pasetti, Marcela, Shriver, Mallory C, Coler, Rhea, Berube, Bryan J, Richardson, Barbra A, Beigi, Richard H, Neuzil, Kathy M, Brown, Elizabeth R“…The risk reduction for COVID-19 in infants by antibody titers at delivery was estimated using a calendar-time Cox regression model after adjusting for maternal age, booster status, and recency of last dose. …”
Publicado 2023
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87663por Yang, Rongrong, Lin, Jing, Yang, Hongxi, Dunk, Michelle M., Wang, Jiao, Xu, Weili, Wang, Yaogang“…Data were analyzed using Cox regression and Laplace regression. RESULTS: During follow-up (median 8.40 years, interquartile range 6.89 to 11.02 years), 3348 (2.4%) participants in the normoglycemia group and 2496 (15.5%) in the prediabetes group developed type 2 diabetes. …”
Publicado 2023
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87664por Pennells, Lisa, Kaptoge, Stephen, White, Ian R., Thompson, Simon G., Wood, Angela M., Tipping, Robert W., Folsom, Aaron R., Couper, David J., Ballantyne, Christie M., Coresh, Josef, Goya Wannamethee, S., Morris, Richard W., Kiechl, Stefan, Willeit, Johann, Willeit, Peter, Schett, Georg, Ebrahim, Shah, Lawlor, Debbie A., Yarnell, John W., Gallacher, John, Cushman, Mary, Psaty, Bruce M., Tracy, Russ, Tybjærg-Hansen, Anne, Price, Jackie F., Lee, Amanda J., McLachlan, Stela, Khaw, Kay-Tee, Wareham, Nicholas J., Brenner, Hermann, Schöttker, Ben, Müller, Heiko, Jansson, Jan-Håkan, Wennberg, Patrik, Salomaa, Veikko, Harald, Kennet, Jousilahti, Pekka, Vartiainen, Erkki, Woodward, Mark, D'Agostino, Ralph B., Bladbjerg, Else-Marie, Jørgensen, Torben, Kiyohara, Yutaka, Arima, Hisatomi, Doi, Yasufumi, Ninomiya, Toshiharu, Dekker, Jacqueline M., Nijpels, Giel, Stehouwer, Coen D. A., Kauhanen, Jussi, Salonen, Jukka T., Meade, Tom W., Cooper, Jackie A., Cushman, Mary, Folsom, Aaron R., Psaty, Bruce M., Shea, Steven, Döring, Angela, Kuller, Lewis H., Grandits, Greg, Gillum, Richard F., Mussolino, Michael, Rimm, Eric B., Hankinson, Sue E., Manson, JoAnn E., Pai, Jennifer K., Kirkland, Susan, Shaffer, Jonathan A., Shimbo, Daichi, Bakker, Stephan J. L., Gansevoort, Ron T., Hillege, Hans L., Amouyel, Philippe, Arveiler, Dominique, Evans, Alun, Ferrières, Jean, Sattar, Naveed, Westendorp, Rudi G., Buckley, Brendan M., Cantin, Bernard, Lamarche, Benoît, Barrett-Connor, Elizabeth, Wingard, Deborah L., Bettencourt, Richele, Gudnason, Vilmundur, Aspelund, Thor, Sigurdsson, Gunnar, Thorsson, Bolli, Kavousi, Maryam, Witteman, Jacqueline C., Hofman, Albert, Franco, Oscar H., Howard, Barbara V., Zhang, Ying, Best, Lyle, Umans, Jason G., Onat, Altan, Sundström, Johan, Michael Gaziano, J., Stampfer, Meir, Ridker, Paul M., Michael Gaziano, J., Ridker, Paul M., Marmot, Michael, Clarke, Robert, Collins, Rory, Fletcher, Astrid, Brunner, Eric, Shipley, Martin, Kivimäki, Mika, Ridker, Paul M., Buring, Julie, Cook, Nancy, Ford, Ian, Shepherd, James, Cobbe, Stuart M., Robertson, Michele, Walker, Matthew, Watson, Sarah, Alexander, Myriam, Butterworth, Adam S., Angelantonio, Emanuele Di, Gao, Pei, Haycock, Philip, Kaptoge, Stephen, Pennells, Lisa, Thompson, Simon G., Walker, Matthew, Watson, Sarah, White, Ian R., Wood, Angela M., Wormser, David, Danesh, John“…We derive risk prediction models using Cox proportional hazards regression analysis stratified by study and obtain estimates of risk discrimination, Harrell's concordance index, and Royston's discrimination measure within each study; we then combine the estimates across studies using a weighted meta-analysis. …”
Publicado 2014
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87665por Forouhi, Nita G, Koulman, Albert, Sharp, Stephen J, Imamura, Fumiaki, Kröger, Janine, Schulze, Matthias B, Crowe, Francesca L, Huerta, José María, Guevara, Marcela, Beulens, Joline WJ, van Woudenbergh, Geertruida J, Wang, Laura, Summerhill, Keith, Griffin, Julian L, Feskens, Edith JM, Amiano, Pilar, Boeing, Heiner, Clavel-Chapelon, Françoise, Dartois, Laureen, Fagherazzi, Guy, Franks, Paul W, Gonzalez, Carlos, Jakobsen, Marianne Uhre, Kaaks, Rudolf, Key, Timothy J, Khaw, Kay-Tee, Kühn, Tilman, Mattiello, Amalia, Nilsson, Peter M, Overvad, Kim, Pala, Valeria, Palli, Domenico, Quirós, J Ramón, Rolandsson, Olov, Roswall, Nina, Sacerdote, Carlotta, Sánchez, María-José, Slimani, Nadia, Spijkerman, Annemieke MW, Tjonneland, Anne, Tormo, Maria-José, Tumino, Rosario, van der A, Daphne L, van der Schouw, Yvonne T, Langenberg, Claudia, Riboli, Elio, Wareham, Nicholas J“…We estimated country-specific hazard ratios (HRs) for associations per SD of each SFA with incident type 2 diabetes using Prentice-weighted Cox regression, which is weighted for case-cohort sampling, and pooled our findings using random-effects meta-analysis. …”
Publicado 2014
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87666“…Fecundability odds ratios (FORs) were estimated using Cox proportional hazard models for discrete time. …”
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87667por Huang, Yunda, Follmann, Dean, Nason, Martha, Zhang, Lily, Huang, Ying, Mehrotra, Devan V., Moodie, Zoe, Metch, Barbara, Janes, Holly, Keefer, Michael C., Churchyard, Gavin, Robb, Merlin L., Fast, Patricia E., Duerr, Ann, McElrath, M. Juliana, Corey, Lawrence, Mascola, John R., Graham, Barney S., Sobieszczyk, Magdalena E., Kublin, James G., Robertson, Michael, Hammer, Scott M., Gray, Glenda E., Buchbinder, Susan P., Gilbert, Peter B.“…The modified-intention-to-treat (MITT) cohort included all randomly assigned participants HIV-1 uninfected at study entry, who received at least the first vaccine/placebo, and the Ad5 cohort included MITT participants who received at least one dose of rAd5-HIV vaccine or rAd5-placebo. Multivariable Cox regression models were used to estimate hazard ratios (HRs) of HIV-1 infection (vaccine vs. placebo) and evaluate HR variation across vaccine regimens, time since vaccination, and subgroups using interaction tests. …”
Publicado 2015
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87668por Chen, Zhengming, Peto, Richard, Zhou, Maigeng, Iona, Andri, Smith, Margaret, Yang, Ling, Guo, Yu, Chen, Yiping, Bian, Zheng, Lancaster, Garry, Sherliker, Paul, Pang, Shutao, Wang, Hao, Su, Hua, Wu, Ming, Wu, Xianping, Chen, Junshi, Collins, Rory, Li, Liming“…METHODS: Two nationwide prospective studies 15 years apart recruited 220 000 men in about 1991 at ages 40–79 years (first study) and 210 000 men and 300 000 women in about 2006 at ages 35–74 years (second study), with follow-up during 1991–99 (mid-year 1995) and 2006–14 (mid-year 2010), respectively. Cox regression yielded sex-specific adjusted mortality rate ratios (RRs) comparing smokers (including any who had stopped because of illness, but not the other ex-smokers, who are described as having stopped by choice) versus never-smokers. …”
Publicado 2015
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87669por Yuen, Courtney M., Kurbatova, Ekaterina V., Tupasi, Thelma, Caoili, Janice Campos, Van Der Walt, Martie, Kvasnovsky, Charlotte, Yagui, Martin, Bayona, Jaime, Contreras, Carmen, Leimane, Vaira, Ershova, Julia, Via, Laura E., Kim, HeeJin, Akksilp, Somsak, Kazennyy, Boris Y., Volchenkov, Grigory V., Jou, Ruwen, Kliiman, Kai, Demikhova, Olga V., Vasilyeva, Irina A., Dalton, Tracy, Cegielski, J. Peter“…The primary outcome of interest was initial sputum culture conversion. We used Cox proportional hazards regression, stratifying by country to control for setting-associated confounders, and adjusting for the number of drugs to which patients’ baseline isolates were resistant, baseline resistance pattern, previous treatment history, sputum smear result, and extent of disease on chest radiograph. …”
Publicado 2015
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87670por James, Nicholas D, Sydes, Matthew R, Clarke, Noel W, Mason, Malcolm D, Dearnaley, David P, Spears, Melissa R, Ritchie, Alastair W S, Parker, Christopher C, Russell, J Martin, Attard, Gerhardt, de Bono, Johann, Cross, William, Jones, Rob J, Thalmann, George, Amos, Claire, Matheson, David, Millman, Robin, Alzouebi, Mymoona, Beesley, Sharon, Birtle, Alison J, Brock, Susannah, Cathomas, Richard, Chakraborti, Prabir, Chowdhury, Simon, Cook, Audrey, Elliott, Tony, Gale, Joanna, Gibbs, Stephanie, Graham, John D, Hetherington, John, Hughes, Robert, Laing, Robert, McKinna, Fiona, McLaren, Duncan B, O'Sullivan, Joe M, Parikh, Omi, Peedell, Clive, Protheroe, Andrew, Robinson, Angus J, Srihari, Narayanan, Srinivasan, Rajaguru, Staffurth, John, Sundar, Santhanam, Tolan, Shaun, Tsang, David, Wagstaff, John, Parmar, Mahesh K B“…Statistical analyses were undertaken with standard log-rank-type methods for time-to-event data, with hazard ratios (HRs) and 95% CIs derived from adjusted Cox models. This trial is registered at ClinicalTrials.gov (NCT00268476) and ControlledTrials.com (ISRCTN78818544). …”
Publicado 2016
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87671por Oedegaard, Ketil J., Alda, Martin, Anand, Anit, Andreassen, Ole A., Balaraman, Yokesh, Berrettini, Wade H., Bhattacharjee, Abesh, Brennand, Kristen J., Burdick, Katherine E., Calabrese, Joseph R., Calkin, Cynthia V., Claasen, Ana, Coryell, William H., Craig, David, DeModena, Anna, Frye, Mark, Gage, Fred H., Gao, Keming, Garnham, Julie, Gershon, Elliot, Jakobsen, Petter, Leckband, Susan G., McCarthy, Michael J., McInnis, Melvin G., Maihofer, Adam X., Mertens, Jerome, Morken, Gunnar, Nievergelt, Caroline M., Nurnberger, John, Pham, Son, Schoeyen, Helle, Shekhtman, Tatyana, Shilling, Paul D., Szelinger, Szabolcs, Tarwater, Bruce, Yao, Jun, Zandi, Peter P., Kelsoe, John R.“…The outcome for lithium response will be analyzed as a time to event, where the event is defined as clinical relapse, using a Cox Proportional Hazards model. Positive single nucleotide polymorphisms (SNPs) from past genetic retrospective studies of lithium response, the Consortium on Lithium Genetics (ConLiGen), will be tested in this prospective study sample; a meta-analysis of these samples will then be performed. …”
Publicado 2016
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87672por Gnanapragasam, Vincent J., Lophatananon, Artitaya, Wright, Karen A., Muir, Kenneth R., Gavin, Anna, Greenberg, David C.“…The results were analysed using a Cox hazards model, the log-rank test, Kaplan-Meier curves, competing-risks regression, and concordance indices. …”
Publicado 2016
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87673por Boeree, Martin J, Heinrich, Norbert, Aarnoutse, Rob, Diacon, Andreas H, Dawson, Rodney, Rehal, Sunita, Kibiki, Gibson S, Churchyard, Gavin, Sanne, Ian, Ntinginya, Nyanda E, Minja, Lilian T, Hunt, Robert D, Charalambous, Salome, Hanekom, Madeleine, Semvua, Hadija H, Mpagama, Stellah G, Manyama, Christina, Mtafya, Bariki, Reither, Klaus, Wallis, Robert S, Venter, Amour, Narunsky, Kim, Mekota, Anka, Henne, Sonja, Colbers, Angela, van Balen, Georgette Plemper, Gillespie, Stephen H, Phillips, Patrick P J, Hoelscher, Michael“…Time-to-event data were analysed using a Cox proportional-hazards regression model and adjusted for minimisation variables. …”
Publicado 2017
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87674por Compostella, Leonida, Lakusic, Nenad, Compostella, Caterina, Truong, Li Van Stella, Iliceto, Sabino, Bellotto, Fabio“…Female sex and history of diabetes maintained a significant correlation with lower values of SDNN at multivariate Cox regression analysis (respectively: P = 0.008 and P = 0.008), while no correlation was found between depressed SDNN and history of previous MI (P = 0.999) or number of diseased coronary arteries (P = 0.428) or unsuccessful percutaneous coronary intervention (PCI) (P = 0.691). …”
Publicado 2017
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87675por Rahmi, Eldiza Puji, Jamal, Jamia Azdina, Kumolosasi, Endang, Jalil, Juriyati, Aladdin, Nor-Ashila“…[Image: see text] Abbreviations used: BSA: Bovine serum albumin, COX-2: Cyclooxygenase-2, CPM: Count per minute, DAMP: Danger-associated molecular pattern, DCM: Dichloromethane, DMSO: Dimethyl sulfoxide, ELISA: Enzyme-linked immunosorbent assay, FBS: Fetal bovine serum, H(2)O: Water, HEPES: 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid, HMC-1: Human mast cell-1, HMGB1: High-mobility group box 1, ICAM: Intercellular adhesion molecule, IFN: Interferon, IgG: Immunoglobulin G, IKK: IkB kinase, IL: Interleukin, iNOS: Inducible nitric oxide synthase, LPS: Lipopolysaccharide, MeOH: Methanol, MPA: Marantodes pumilum var. alata, MPL: Marantodes pumilum var. lanceolata, MPP: Marantodes pumilum var. pumila, MSU: Monosodium urate, MTT: Methylthiazole tetrazolium, NF-κB: Nuclear factor-kappa B, NLR: NOD-like receptor, NLRP3: NLR family pyrin domain containing protein 3, NO: Nitric oxide, NOD: Nucleotide-binding oligomerization domain, NSAID: Nonsteroidal anti-inflammatory drug, PAMP: Pathogen-associated molecular pattern, PBMC: Peripheral blood mononuclear cell, PBS: Phosphate buffered saline, PGE(2): Prostaglandin E(2,) PMACI: Phorbol-12-myristate 13-acetate and calcium ionosphere A23187, PRR: Pathogen recognition receptor, PTFE: Polytetrafluoroethylene, RIA: Radioimmunoassay, RIG: Retinoic acid-inducible gene I, RLR: RIG I-like receptor, RP-HPLC: Reversed-phase high-performance liquid chromatography, RPMI-1640: Roswell Park Memorial Institute-1640, TLR: Toll-like receptor, TNF: Tumor necrosis factor, VCAM: Vascular cell adhesion molecule.…”
Publicado 2017
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87676por García, Concepción, Gómez-Cañas, María, Burgaz, Sonia, Palomares, Belén, Gómez-Gálvez, Yolanda, Palomo-Garo, Cristina, Campo, Sara, Ferrer-Hernández, Joel, Pavicic, Carolina, Navarrete, Carmen, Luz Bellido, M., García-Arencibia, Moisés, Ruth Pazos, M., Muñoz, Eduardo, Fernández-Ruiz, Javier“…VCE-003.2 was able to attenuate the synthesis and release of TNF-α and IL-1β, as well as the induction of iNOS and cyclooxygenase-2 (COX-2) elicited by LPS in these cells. However, we found such effects were not reversed by GW9662, another classic PPARγ antagonist. …”
Publicado 2018
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87677por Boix, Francisco, Llorente, Santiago, Eguía, Jorge, Gonzalez-Martinez, Gema, Alfaro, Rafael, Galián, Jose A, Campillo, Jose A, Moya-Quiles, María Rosa, Minguela, Alfredo, Pons, Jose A, Muro, Manuel“…The auROC curve model determined the most accurate cut-off values to stratify LTr and KTr at high risk of OI and Cox Regression model confirmed these biomarkers as the most significant risk factors to opportunistic infection. …”
Publicado 2018
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87678por de Boer, Stephanie M, Powell, Melanie E, Mileshkin, Linda, Katsaros, Dionyssios, Bessette, Paul, Haie-Meder, Christine, Ottevanger, Petronella B, Ledermann, Jonathan A, Khaw, Pearly, Colombo, Alessandro, Fyles, Anthony, Baron, Marie-Helene, Jürgenliemk-Schulz, Ina M, Kitchener, Henry C, Nijman, Hans W, Wilson, Godfrey, Brooks, Susan, Carinelli, Silvestro, Provencher, Diane, Hanzen, Chantal, Lutgens, Ludy C H W, Smit, Vincent T H B M, Singh, Naveena, Do, Viet, D'Amico, Romerai, Nout, Remi A, Feeney, Amanda, Verhoeven-Adema, Karen W, Putter, Hein, Creutzberg, Carien L“…We used the Kaplan-Meier method, log-rank test, and Cox regression analysis for final analysis by intention to treat and adjusted for stratification factors. …”
Publicado 2018
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87679por Ripoll, Oleguer Plana, Pedersen, Carsten, Agerbo, Esben, Laursen, Thomas Munk, Mortensen, Preben Bo, McGrath, John“…Hazard ratios (HR) were estimated using Cox Proportional Hazards models with age as time scale, and adjusting for sex, calendar time and other psychiatric comorbidity. …”
Publicado 2018
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87680Publicado 2011“…The results of multivariable Cox model analysis showed that "personalized molecular P-TNM staging", micrometastasis in peripheral blood, pathological types of the tumor and mediastinal lymph node metastasis of the cancer were the most significant factors for predicting prognosis in the patients with locally advanced nonsmall lung cancer. …”
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