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87701por Sanz-Pamplona, Rebeca, Melas, Marilena, Maoz, Asaf, Schmit, Stephanie L., Rennert, Hedy, Lejbkowicz, Flavio, Greenson, Joel K., Sanjuan, Xavier, Lopez-Zambrano, Maria, Alonso, M. Henar, Qu, Chenxu, McDonnell, Kevin J., Idos, Gregory E., Vignali, Marissa, Emerson, Ryan, Fields, Paul, Guinó, Elisabet, Santos, Cristina, Salazar, Ramon, Robins, Harlan S., Rennert, Gad, Gruber, Stephen B., Moreno, Victor“…Median follow-up time was 81.1 months. Cox regression models were fitted to evaluate the prognostic value of T-cell abundance and Simpson clonality of TCR variants adjusting by sex, age, tumor location, and stage (IIA and IIB). …”
Publicado 2020
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87702por Fan, Junning, Yu, Canqing, Guo, Yu, Bian, Zheng, Sun, Zhijia, Yang, Ling, Chen, Yiping, Du, Huaidong, Li, Zhongxiao, Lei, Yulong, Sun, Dianjianyi, Clarke, Robert, Chen, Junshi, Chen, Zhengming, Lv, Jun, Li, Liming“…The primary outcomes were all-cause mortality and cause-specific mortality in Chinese adults aged 30–79 years. We used a Cox proportional hazards model to estimate the associations between the frailty index and all-cause and cause-specific mortality, adjusting for chronological age, education, and lifestyle factors. …”
Publicado 2020
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87703por Orsatti, Giovanna, Morosi, Carlo, Giraudo, Chiara, Varotto, Alessia, Crimì, Filippo, Bonzini, Miriam, Minotti, Marta, Frigo, Anna Chiara, Zanetti, Ilaria, Chiaravalli, Stefano, Casanova, Michela, Ferrari, Andrea, Bisogno, Gianni, Stramare, Roberto“…Tumor response was compared with survival using Kaplan–Meier plots, the log-rank test, and Cox’s regression. Agreement between methods and observers (weighted-κ) was also calculated. …”
Publicado 2020
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87704por Cai, Miao, Xie, Yan, Bowe, Benjamin, Gibson, Andrew K., Zayed, Mohamed A., Li, Tingting, Al-Aly, Ziyad“…DESIGN, SETTING, AND PARTICIPANTS: This cohort study used VA data from 2008 to 2018 to estimate incidence rates of LEA among veterans using VA services. Cox regression models were used to identify risk factors associated with LEA. …”
Publicado 2021
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87705por Cavalli, Giulio, Larcher, Alessandro, Tomelleri, Alessandro, Campochiaro, Corrado, Della-Torre, Emanuel, De Luca, Giacomo, Farina, Nicola, Boffini, Nicola, Ruggeri, Annalisa, Poli, Andrea, Scarpellini, Paolo, Rovere-Querini, Patrizia, Tresoldi, Moreno, Salonia, Andrea, Montorsi, Francesco, Landoni, Giovanni, Castagna, Antonella, Ciceri, Fabio, Zangrillo, Alberto, Dagna, Lorenzo“…The primary endpoint was survival, and the secondary endpoint was a composite of death or mechanical ventilation (adverse clinical outcome). Multivariable Cox regression analysis was used to compare clinical outcomes of patients receiving IL-1 inhibition (anakinra) or IL-6 inhibition (tocilizumab or sarilumab) with those of patients who did not receive interleukin inhibitors, after accounting for baseline differences. …”
Publicado 2021
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87706por Kharbanda, Elyse O., Vazquez-Benitez, Gabriela, DeSilva, Malini B., Naleway, Allison L., Klein, Nicola P., Hechter, Rulin C., Glanz, Jason M., Donahue, James G., Jackson, Lisa A., Sheth, Sangini S., Greenberg, Victoria, Panagiotakopoulos, Lakshmi, Mba-Jonas, Adamma, Lipkind, Heather S.“…Time-dependent covariate Cox proportional hazards regression models and Poisson regression were used to estimate the associations between 9vHPV vaccine exposures and pregnancy and birth outcomes. …”
Publicado 2021
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87707por Pinato, David J., Scotti, Lorenza, Gennari, Alessandra, Colomba-Blameble, Emeline, Dolly, Saoirse, Loizidou, Angela, Chester, John, Mukherjee, Uma, Zambelli, Alberto, Aguilar-Company, Juan, Bower, Mark, Galazi, Myria, Salazar, Ramon, Bertuzzi, Alexia, Brunet, Joan, Mesia, Ricard, Sita-Lumsden, Ailsa, Colomba, Johann, Pommeret, Fanny, Seguí, Elia, Biello, Federica, Generali, Daniele, Grisanti, Salvatore, Rizzo, Gianpiero, Libertini, Michela, Moss, Charlotte, Evans, Joanne S., Russell, Beth, Wuerstlein, Rachel, Vincenzi, Bruno, Bertulli, Rossella, Ottaviani, Diego, Liñan, Raquel, Marrari, Andrea, Carmona-García, M.C., Sng, Christopher. C.T., Tondini, Carlo, Mirallas, Oriol, Tovazzi, Valeria, Fotia, Vittoria, Cruz, Claudia A., Saoudi-Gonzalez, Nadia, Felip, Eudald, R. Lloveras, Ariadna, Lee, Alvin. J.X., Newsom-Davis, Thomas, Sharkey, Rachel, Chung, Chris, García-Illescas, David, Reyes, Roxana, Sophia Wong, Yien N., Ferrante, Daniela, Marco-Hernández, Javier, Ruiz-Camps, Isabel, Gaidano, Gianluca, Patriarca, Andrea, Sureda, Anna, Martinez-Vila, Clara, Sanchez de Torre, Ana, Rimassa, Lorenza, Chiudinelli, Lorenzo, Franchi, Michela, Krengli, Marco, Santoro, Armando, Prat, Aleix, Tabernero, Josep, V. Hemelrijck, Mieke, Diamantis, Nikolaos, Cortellini, Alessio“…We compared patient characteristics at baseline including oncological and COVID-19–specific therapy across UK and EU cohorts and evaluated the association of these factors with the risk of adverse outcomes in multivariable Cox regression models. FINDINGS: Compared with EU (n = 924), UK patients (n = 468) were characterised by higher case fatality rates (40.38% versus 26.5%, p < 0.0001) and higher risk of death at 30 days (hazard ratio [HR], 1.64 [95% confidence interval {CI}, 1.36–1.99]) and 6 months after COVID-19 diagnosis (47.64% versus 33.33%; p < 0.0001; HR, 1.59 [95% CI, 1.33–1.88]). …”
Publicado 2021
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87708por Ostheimer, C., Mäurer, M., Ebert, N., Schmitt, D., Krug, D., Baumann, R., Henkenberens, C., Giordano, F. A., Sautter, L., López, Guerra, Fleischmann, D. F., Niyazi, M., Käsmann, L., Kaul, D., Thieme, A. H., Billiet, C., Dobiasch, S., Arnold, C. R., Oertel, M., Haussmann, J., Gauer, T., Goy, Y., Suess, C., Ziegler, S., Panje, C. M., Baues, C., Trommer, M., Skripcak, T., Medenwald, D.“…Hazard ratios (HR) of survival analysis were estimated by means of adjusted Cox regression models. RESULTS: GTV1 was found to have a mean of 154.4 ml (95%CI: 1.5–877) and GTV2 of 106.2 ml (95% CI: 0.5–589.5), resulting in an estimated reduction of 48.2 ml (p < 0.001). …”
Publicado 2021
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87709por Li Bassi, Gianluigi, Suen, Jacky Y., Dalton, Heidi J., White, Nicole, Shrapnel, Sally, Fanning, Jonathon P., Liquet, Benoit, Hinton, Samuel, Vuorinen, Aapeli, Booth, Gareth, Millar, Jonathan E., Forsyth, Simon, Panigada, Mauro, Laffey, John, Brodie, Daniel, Fan, Eddy, Torres, Antoni, Chiumello, Davide, Corley, Amanda, Elhazmi, Alyaa, Hodgson, Carol, Ichiba, Shingo, Luna, Carlos, Murthy, Srinivas, Nichol, Alistair, Ng, Pauline Yeung, Ogino, Mark, Pesenti, Antonio, Trieu, Huynh Trung, Fraser, John F.“…Overall, 28-day ICU mortality, accounting for the competing risk of being discharged within the period, was 35.6% (SE 1.7). Cox proportional hazard analysis demonstrated that C(RS) (+ 10 mL/cm H(2)O) was only associated with being discharge from the ICU within 28 days (HR 1.14, 95% CI 1.02–1.28, p = 0.018). …”
Publicado 2021
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87710por Shrotri, Madhumita, Krutikov, Maria, Palmer, Tom, Giddings, Rebecca, Azmi, Borscha, Subbarao, Sathyavani, Fuller, Christopher, Irwin-Singer, Aidan, Davies, Daniel, Tut, Gokhan, Lopez Bernal, Jamie, Moss, Paul, Hayward, Andrew, Copas, Andrew, Shallcross, Laura“…In this cohort study, we included long-term care facility residents undergoing routine asymptomatic SARS-CoV-2 testing between Dec 8, 2020 (the date the vaccine was first deployed in a long-term care facility), and March 15, 2021, using national testing data linked within the COVID-19 Datastore. Using Cox proportional hazards regression, we estimated the relative hazard of PCR-positive infection at 0–6 days, 7–13 days, 14–20 days, 21–27 days, 28–34 days, 35–48 days, and 49 days and beyond after vaccination, comparing unvaccinated and vaccinated person-time from the same cohort of residents, adjusting for age, sex, previous infection, local SARS-CoV-2 incidence, long-term care facility bed capacity, and clustering by long-term care facility. …”
Publicado 2021
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87711por Dar, Huma, Johansson, Annelie, Nordenskjöld, Anna, Iftimi, Adina, Yau, Christina, Perez-Tenorio, Gizeh, Benz, Christopher, Nordenskjöld, Bo, Stål, Olle, Esserman, Laura J., Fornander, Tommy, Lindström, Linda S.“…MAIN OUTCOMES AND MEASURES: Distant recurrence–free interval (DRFI) by clinically used breast cancer markers was assessed using Kaplan-Meier and multivariable Cox proportional hazards analyses adjusted for age, period of primary diagnosis, tumor size (T1a and T1b [T1a/b], T1c, and T2), tumor grade (1-3), PR status (positive vs negative), Ki-67 status (low vs medium to high), and STO-3 clinical trial arm (tamoxifen treatment vs no adjuvant treatment). …”
Publicado 2021
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87712por Schrijver, Lieske H., Antoniou, Antonis C., Olsson, Håkan, Mooij, Thea M., Roos-Blom, Marie-José, Azarang, Leyla, Adlard, Julian, Ahmed, Munaza, Barrowdale, Daniel, Davidson, Rosemarie, Donaldson, Alan, Eeles, Ros, Evans, D. Gareth, Frost, Debra, Henderson, Alex, Izatt, Louise, Ong, Kai-Ren, Bonadona, Valérie, Coupier, Isabelle, Faivre, Laurence, Fricker, Jean-Pierre, Gesta, Paul, van Engelen, Klaartje, Jager, Agnes, Menko, Fred H., Mourits, Marian J.E., Singer, Christian F., Tan, Yen Y., Foretova, Lenka, Navratilova, Marie, Schmutzler, Rita K., Ellberg, Carolina, Gerdes, Anne-Marie, Caldes, Trinidad, Simard, Jacques, Olah, Edith, Jakubowska, Anna, Rantala, Johanna, Osorio, Ana, Hopper, John L., Phillips, Kelly-Anne, Milne, Roger L., Beth Terry, Mary, Noguès, Catherine, Engel, Christoph, Kast, Karin, Goldgar, David E., van Leeuwen, Flora E., Easton, Douglas F., Andrieu, Nadine, Rookus, Matti A.“…Age-dependent–weighted Cox regression analyses were stratified by study and birth cohort and included breast cancer diagnosis as a covariate. …”
Publicado 2021
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87713por Beaumont, A., Vignes, D., Sterpu, R., Roy, S., Guillet-Caruba, C., Téglas, J., Abgrall, S.“…Les facteurs associés à une forme grave, définie par la survenue du décès ou la nécessité d’une ventilation mécanique, ont été étudiés à l’aide de modèles de Cox. RÉSULTATS: Parmi 399 patients inclus à partir des urgences, 78 patients sont retournés au domicile et 25 ont été transférés dans un autre hôpital. …”
Publicado 2021
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87714por Li, Yang, Sun, Xiao-Lu, Qiu, Hong, Qin, Jian, Li, Chun-Sheng, Yu, Xue-Zhong, Wang, Guo-Xing, Fu, Yan, Zheng, Ya-An, Zhao, Bin, Yu, Dong-Ming, Wang, Si-Jia, Wang, Guo-Gan“…METHODS: This prospective, multicenter, cohort study consecutively enrolled 3335 patients with AHF who were admitted to EDs of 14 hospitals from Beijing between January 1, 2011 and September 23, 2012. Kaplan-Meier and Cox regression analysis were adopted to evaluate 5-year outcomes and associated predictors. …”
Publicado 2021
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87715por Fleming, Christina A., O’Connell, Emer P., Kavanagh, Richard G., O’Leary, Donal P., Twomey, Maria, Corrigan, Mark A., Wang, Jiang H., Maher, Michael M., O’Connor, Owen J., Redmond, Henry P.“…MAIN OUTCOMES AND MEASURES: The associations of body composition profiles with 5-year cancer recurrence and disease-specific mortality were analyzed using Mantel Cox log-rank test and Kaplan-Meier curves. RESULTS: A total of 28 patients were included (median [interquartile range] age, 67 [58-72] years; 22 [78.6%] men). …”
Publicado 2021
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87716por Fischer, Johannes C., Schmidt, Albrecht G., Bölke, Edwin, Uhrberg, Markus, Keitel, Verena, Feldt, Torsten, Jensen, Björn, Häussinger, Dieter, Adams, Ortwin, Schneider, E. Marion, Balz, Vera, Enczmann, Jürgen, Rox, Jutta, Hermsen, Derik, Schulze-Bosse, Karin, Kindgen-Milles, Detlef, Knoefel, Wolfram Trudo, van Griensven, Martijn, Haussmann, Jan, Tamaskovics, Balint, Plettenberg, Christian, Scheckenbach, Kathrin, Corradini, Stefanie, Pedoto, Alessia, Maas, Kitti, Schmidt, Livia, Grebe, Olaf, Esposito, Irene, Ehrhardt, Anja, Peiper, Matthias, Buhren, Bettina Alexandra, Calles, Christian, Stöhr, Andreas, Lichtenberg, Artur, Freise, Noemi F., Lutterbeck, Matthias, Rezazadeh, Amir, Budach, Wilfried, Matuschek, Christiane“…Hierarchical testing by Cox regression analyses confirmed the significance of the protective effect of the HLA alleles identified (when assessed in composite) in terms of disease duration, whereas AB0 blood group antigen heterozygosity was found to be significantly associated with disease severity (rather than duration) in our cohort. …”
Publicado 2021
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87717por Eriksson, L. S. E., Nastic, D., Lindqvist, P. G., Imboden, S., Järnbert‐Pettersson, H., Carlson, J. W., Epstein, E.“…Demographic and preoperative sonographic characteristics, tumor recurrence or progression and survival were compared between the ProMisE subgroups. Cox regression analysis was used to identify prognostic factors associated with recurrence or progression, using univariable models to study crude associations and multivariable models to study adjusted associations. …”
Publicado 2021
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87718por Lindbohm, Joni V, Sipilä, Pyry N, Mars, Nina, Knüppel, Anika, Pentti, Jaana, Nyberg, Solja T, Frank, Philipp, Ahmadi-Abhari, Sara, Brunner, Eric J, Shipley, Martin J, Singh-Manoux, Archana, Tabak, Adam G, Batty, G David, Kivimäki, Mika“…We assessed the levels of, and 5-year changes in, SCORE and ASCVD risk scores as predictors of cardiovascular disease and disease-free life-years using Cox proportional hazards and flexible parametric survival models. …”
Publicado 2021
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87719por Vuori, Matti A., Reinikainen, Jaakko, Söderberg, Stefan, Bergdahl, Ellinor, Jousilahti, Pekka, Tunstall-Pedoe, Hugh, Zeller, Tanja, Westermann, Dirk, Sans, Susana, Linneberg, Allan, Iacoviello, Licia, Costanzo, Simona, Salomaa, Veikko, Blankenberg, Stefan, Kuulasmaa, Kari, Niiranen, Teemu J.“…In the multivariable-adjusted Cox models, conventional cardiovascular disease risk factors, such as smoking (diabetes: HR 2.07 [1.59–2.69]; non-diabetes: HR 1.85 [1.68–2.02]), BMI (diabetes: HR 1.30 [1.18–1.42]; non-diabetes: HR 1.40 [1.35–1.47]), baseline myocardial infarction (diabetes: HR 2.06 [1.55–2.75]; non-diabetes: HR 2.86 [2.50–3.28]), and baseline atrial fibrillation (diabetes: HR 1.51 [0.82–2.80]; non-diabetes: HR 2.97 [2.21–4.00]) had the strongest associations with incident heart failure. …”
Publicado 2021
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87720por Michels, Naomi, Boer, Judith M, Enshaei, Amir, Sutton, Rosemary, Heyman, Mats, Ebert, Sabine, Fiocco, Marta, de Groot-Kruseman, Hester A, van der Velden, Vincent H J, Barbany, Gisela, Escherich, Gabriele, Vora, Ajay, Trahair, Toby, Dalla-Pozza, Luciano, Pieters, Rob, zur Stadt, Udo, Schmiegelow, Kjeld, Moorman, Anthony V, Zwaan, C Michel, den Boer, Monique L“…We used mixed-effect models, Cox models, and competing risk for statistical analyses. …”
Publicado 2021
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