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Mostrando 881 - 900 Resultados de 89,050 Para Buscar '"Cox"', tiempo de consulta: 0.79s Limitar resultados
  1. 881
    “…The purpose of the research was to explore the therapeutic action of simvastatin-loaded poly(ethylene glycol)-b-poly(gamma-benzyl l-glutamate) (PEG-b-PBLG(50)) on intestinal ischemia/reperfusion injury (II/RI) through downregulating bone morphogenetic protein 4 (BMP4)/cyclooxygenase-2 (COX-2) pathway as compared to free simvastatin (Sim). …”
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    Simvastatin nanoparticles attenuated intestinal ischemia/reperfusion injury by downregulating BMP4/COX-2 pathway in rats
  2. 882
    “…Genomic DNA was extracted from the samples, a genomic region from the 5’ region of the cox1 gene was amplified and sequenced, and this was then used to analyse genetic variation. …”
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    Assessing the species composition of tropical eels (Anguillidae) in Aceh Waters, Indonesia, with DNA barcoding gene cox1.
  3. 883
    “…BACKGROUND: Finding the most appropriate regression model for survival data in cancer casesin order to determine prognosis is an important issue in medical research. Here we compare Cox and parametric regression models regarding survival of children with acute leukemia in southern Iran. …”
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    Comparison of Cox Regression and Parametric Models: Application for Assessment of Survival of Pediatric Cases of Acute Leukemia in Southern Iran
  4. 884
    “…Logistic regression is often used instead of Cox regression to analyse genome-wide association studies (GWAS) of single-nucleotide polymorphisms (SNPs) and disease outcomes with cohort and case-cohort designs, as it is less computationally expensive. …”
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    A comparison of Cox and logistic regression for use in genome-wide association studies of cohort and case-cohort design
  5. 885
    “…Extracellular histones raised cyclooxygenase‐2 (COX‐2) and prostacyclin synthase (PGIS) mRNA and protein expression, decreased COX‐1 mRNA levels and did not change thromboxane A2 synthase (TXAS) expression. …”
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    Extracellular histones disarrange vasoactive mediators release through a COX‐NOS interaction in human endothelial cells
  6. 886
    “…BACKGROUND: Epidemiological studies have shown that individuals who regularly consume NSAIDs have lower rates of mortality associated with colorectal cancer. Because COX-2 inhibitors prevent tumor growth through some mechanisms, we assessed the effect of JTE-522, a selective COX-2 inhibitor, on pulmonary metastases of colon cancer in a rat model. …”
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    JTE-522, a selective COX-2 inhibitor, inhibits growth of pulmonary metastases of colorectal cancer in rats
  7. 887
    “…Trying to utilize such information in the censored data, a semi-supervised learning framework (Cox-AFT model) combined with Cox proportional hazard (Cox) and accelerated failure time (AFT) model was used in cancer research, which has better performance than the single Cox or AFT model. …”
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    A new semi-supervised learning model combined with Cox and SP-AFT models in cancer survival analysis
  8. 888
    por Budd, Wm.
    Publicado 1807
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    A Case of Disease Produced by Taking One Ounce of Corrosive Sublimate, Successfully Treated. Communicated to Dr. Coxe
  9. 889
    “…CHS inhibited the growth of Human colon adenocarcinoma-7 (HCA-7) cells; the order of potency was turmeric, bay leaf, ginger, sage, and rosemary; their combinations had a synergistic or additive effect on cell growth inhibition. CHS also inhibited COX-2 expression and activity; this action was comparable to that of the specific COX-2 inhibitor Celecoxib. …”
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    Inhibitory Effects of Culinary Herbs and Spices on the Growth of HCA-7 Colorectal Cancer Cells and Their COX-2 Expression
  10. 890
    “…Standard survival models like the linear Cox proportional hazards model require extensive feature engineering or prior medical knowledge to model treatment interaction at an individual level. …”
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    DeepSurv: personalized treatment recommender system using a Cox proportional hazards deep neural network
  11. 891
    “…The differential expression of two closelyassociated cyclooxygenase isozymes, COX-1 and COX-2, exhibited functions beyond eicosanoid metabolism. …”
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    Proteomic Analysis Shows Constitutive Secretion of MIF and p53-associated Activity of COX-2(−/−) Lung Fibroblasts
  12. 892
    por Zhang, Zhan-shan
    Publicado 2018
    “…BACKGROUND: Studies had attempted to clarify the relation between COX2 -765G/C gene polymorphisms and periodontitis risk, but there has been no definite consensus to date. …”
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    Association between COX2 -765G/C polymorphism and periodontitis in Chinese population: a meta-analysis
  13. 893
    “…Since cyclooxygenase-2 (COX-2) expression in the macula densa is frequently increased in states of a defective RAAS, we have investigated a potential role of COX-2 and its derived prostaglandins for renin expression and secretion in aldosterone synthase-deficient mice (AS(−/−)) as a model for a genetic defect of the RAAS. …”
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    COX-2-derived PGE(2) triggers hyperplastic renin expression and hyperreninemia in aldosterone synthase-deficient mice
  14. 894
    “…A porcine sapovirus Cowden strain, a member of genus Sapovirus within the Caliciviridae family, induces strong COX-2/PGE(2) but transient COX-1/PGE(2) signaling to enhance virus replication. …”
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    Feline calicivirus- and murine norovirus-induced COX-2/PGE(2) signaling pathway has proviral effects
  15. 895
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    Berberine ameliorates blockade of autophagic flux in the liver by regulating cholesterol metabolism and inhibiting COX2-prostaglandin synthesis
  16. 896
    “…Both COX-2 and 5-LOX are key enzymes in the production of inflammatory mediators and are known targets in the design of anti-inflammatory drugs. …”
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    Using quantitative systems pharmacology to evaluate the drug efficacy of COX-2 and 5-LOX inhibitors in therapeutic situations
  17. 897
    “…Additionally, we also showed that intranasal delivery of EVs containing lincRNA-Cox2 siRNA (small interfering RNA) was able to restore microglial phagocytic activity in mice administered morphine. …”
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    Astrocyte EV-Induced lincRNA-Cox2 Regulates Microglial Phagocytosis: Implications for Morphine-Mediated Neurodegeneration
  18. 898
    “…Subsequently, an 11-lncRNA signature was identified by LASSO-based Cox-PH model. The lncRNAs signature-based risk score could divide patients into 2 risk groups with significantly different overall survival and recurrence-free survival times. …”
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    LASSO-based Cox-PH model identifies an 11-lncRNA signature for prognosis prediction in gastric cancer
  19. 899
    por Yu, Zhaoyan, Xu, Wei, Wang, Haibo
    Publicado 2018
    “…On the other hand, resveratrol played a vital role in the inhibition of carrageenan induced increase in the expression of COX-2 in mice. The inhibition in the COX-2 expression by 20 mg/kg doses of resveratrol was significantly higher compared to the known drug, votalin. …”
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    Resveratrol treatment inhibits acute pharyngitis in the mice model through inhibition of PGE2/COX-2 expression
  20. 900
    “…We found that Cox UM-MDR has similar power to Cox-MDR without marginal effects, whereas it outperforms Cox-MDR with marginal effects and more robust to heavy censoring. …”
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    Unified Cox model based multifactor dimensionality reduction method for gene-gene interaction analysis of the survival phenotype
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