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  1. 961
    “…Of particular translational relevance, our findings support a model whereby upregulation of COX-2 expression and activity post-chemotherapy impairs the efficacy of the combination of PD-1 blockade and chemotherapy. …”
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    COX-2 upregulation by tumour cells post-chemotherapy fuels the immune evasive dark side of cancer inflammation
  2. 962
    “…METHODS: Welding fume and metal ion concentrations were assessed in a vehicle factory in Wuhan. A Cox regression model estimated lung-related disease risk in workers by independent and combined factors. …”
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    Risk for lung-related diseases associated with welding fumes in an occupational population: Evidence from a Cox model
  3. 963
    “…INTRODUCTION: Growing evidence has shown that cyclooxygenase-2 (COX-2), an enzyme capable of catalyzing prostaglandin production, plays a key role in carcinogenesis. …”
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    Cyclooxygenase-2 (COX-2) Expression in Oral Submucous Fibrosis and Oral Squamous Cell Carcinoma: An Immunohistochemical Study
  4. 964
    por Webb, Annabel, Ma, Jun, Lô, Serigne N.
    Publicado 2022
    “…However, when data contain a cured fraction, standard survival methods such as Cox proportional hazards models can produce biased results and therefore misleading interpretations. …”
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    Penalized likelihood estimation of a mixture cure Cox model with partly interval censoring—An application to thin melanoma
  5. 965
    por Li, Juntao, Zhang, Hongmei, Gao, Fugen
    Publicado 2022
    “…RESULTS: A new method combing ensemble regularized multinomial logistic regression and Cox regression was proposed for identifying miRNA biomarkers in breast cancer. …”
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    Identification of miRNA biomarkers for breast cancer by combining ensemble regularized multinomial logistic regression and Cox regression
  6. 966
    “…BACKGROUND: Cox proportional hazards regression models and machine learning models are widely used for predicting the risk of dementia. …”
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    Dementia risk prediction in individuals with mild cognitive impairment: a comparison of Cox regression and machine learning models
  7. 967
    “…RESULTS: Compared with stable pulmonary nodules, the positive rates of COX-2, Ki67 and VEGF in the growth group were 85%, 80% and 55%, respectively. …”
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    Correlation and significance of COX-2, Ki67, VEGF and other immune indexes with the growth of malignant pulmonary nodules
  8. 968
    “…Furthermore, control monocytes pre-exposed to PGE(2) overexpress COX-2 in response to IL-1α, simulating responses made by monocytes from some OPC patients. …”
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    Oropharyngeal tumor cells induce COX-2 expression in peripheral blood monocytes by secretion of IL-1α
  9. 969
    “…The univariate Kaplan–Meier analysis by log-rank and multivariate stepwise Cox regression analysis were used to explore variables possibly associated with postoperative recurrence in MD individuals. …”
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    Exploration of Influencing Factors for Postoperative Recurrence in Patients with Madelung’s Disease on the Basis of Multivariate Stepwise Cox Regression Analysis
  10. 970
    “…METHOD: First, nomogram model was constructed using the Cox proportional hazards models to identify the independent prognostic factors of breast cancer patients. …”
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    Prognostic analysis of breast cancer in Xinjiang based on Cox proportional hazards model and two−step cluster method
  11. 971
    “…In this context, indole-based small molecules, which were synthesized efficiently, were subjected to an in vitro colorimetric assay to evaluate their cyclooxygenase (COX) inhibitory profiles. Compounds 3b and 4a were found to be the most selective COX-1 inhibitors in this series with IC(50) values of 8.90 µM and 10.00 µM, respectively. …”
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    Discovery of Small Molecule COX-1 and Akt Inhibitors as Anti-NSCLC Agents Endowed with Anti-Inflammatory Action
  12. 972
    “…Cox regression using a calendar time scale was least biased (0.00, +0.12). …”
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    Cox regression using a calendar time scale was unbiased in simulations of COVID-19 vaccine effectiveness & safety
  13. 973
    “…In this study, we used a chemical proteomics approach to search for targets of NBP and identified cytochrome C oxidase 7c (Cox7c) as a key interacting target of NBP. Our findings indicated that NBP inhibits mitochondrial apoptosis and reactive oxygen species (ROS) release and increases ATP production through upregulation of Cox7c. …”
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    Effect of Dl-3-n-butylphthalide on mitochondrial Cox7c in models of cerebral ischemia/reperfusion injury
  14. 974
    Publicado 2023
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    Exploration of Influencing Factors for Postoperative Recurrence in Patients with Madelung’s Disease on the Basis of Multivariate Stepwise Cox Regression Analysis [Corrigendum]
  15. 975
    “…MATERIALS AND METHODS: Data was acquired from Multiparameter Intelligent Monitoring in Intensive Care Database IV (MIMIC-IV) version 1.0. Cox proportional hazards regression was utilized to estimate the relationship between fibrinogen and inhospital mortality. …”
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    Fibrinogen Is Associated with Prognosis of Critically Ill Patients with Sepsis: A Study Based on Cox Regression and Propensity Score Matching
  16. 976
    “…Cardiovascular (CV) disease prevention with low-dose aspirin can be less effective in patients with a faster recovery of platelet (PLT) cyclooxygenase (COX)-1 activity during the 24-hour dosing interval. …”
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    Reduced platelet glycoprotein Ibα shedding accelerates thrombopoiesis and COX-1 recovery: implications for aspirin dosing regimen
  17. 977
    por Kim, Go Oun, Park, Dong Ho, Bae, Jong-Sup
    Publicado 2023
    “…We assessed the effects of CSL on heme oxygenase (HO)-1, cyclooxygenase (COX)-2, and inducible nitric oxide synthase (iNOS) in LPS-activated human umbilical vein endothelial cells (HUVECs). …”
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    Protective Effects of Cirsilineol against Lipopolysaccharide-Induced Inflammation; Insights into HO-1, COX-2, and iNOS Modulation
  18. 978
    “…Genetic deletion or pharmaceutical inhibition of COX-2 significantly reduced HCT in vivo. The COX-2 selective inhibitor etoricoxib suppressed HCT through the TGF-β-TGFBR1-β-catenin pathway in vitro. …”
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    Atypical cholangiocytes derived from hepatocyte-cholangiocyte transdifferentiation mediated by COX-2: a kind of misguided liver regeneration
  19. 979
    “…This study aimed to assess the coverage of OCV among the FDMN and the host community in Cox's Bazar. METHODS: In August 2018, we enrolled 4,240 respondents for this study following the “World Health Organization (WHO) Vaccination Coverage Cluster Surveys: Reference Manual (2018).” …”
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    Oral cholera vaccine coverage evaluation survey: Forcibly Displaced Myanmar Nationals and host community in Cox's Bazar, Bangladesh
  20. 980
    por Ping, Ruru, Oshio, Takashi
    Publicado 2023
    “…BACKGROUND: Despite the importance of midlife with reference to one’s health, educational inequalities in midlife health have attracted little attention in China. Using Cox proportional hazards regression analysis, this study examined the association between educational attainment and the onset of midlife health problems and investigated the potential mediating effects of socioeconomic position (SEP) other than educational attainment, depression, and health behavior. …”
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    Education level as a predictor of the onset of health problems among China’s middle-aged population: Cox regression analysis
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