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  1. 1321
    “…To further confirm prognosis-related TFs, COX regression and LASSO analyses were performed; consequently, a prognostic risk model was constructed, and its validity was verified. …”
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    Identification of Key Transcription Factors and Immune Infiltration Patterns Associated With Breast Cancer Prognosis Using WGCNA and Cox Regression Analysis
  2. 1322
    “…Gene set enrichment analysis (GSEA), univariate Cox proportional hazards regression, and the Bayesian hierarchical Cox proportional hazards model were used to explore the mRNAs related to the prognosis of lung adenocarcinoma. …”
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    A novel 14-gene signature for overall survival in lung adenocarcinoma based on the Bayesian hierarchical Cox proportional hazards model
  3. 1323
    “…Ni@G nanoparticles were used for catalytic decomposition of methane (CDM) to produce COx-free hydrogen and graphene nanoplatelets. Ni@G showed high catalytic activity for methane decomposition at temperatures of 800 to 900 °C and exhibited long-term stability of 600 min time-on-stream (TOS) without apparent deactivation. …”
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    Production of COx-Free Hydrogen and Few-Layer Graphene Nanoplatelets by Catalytic Decomposition of Methane over Ni-Lignin-Derived Nanoparticles
  4. 1324
    “…After lasso regression was used to screen for risk factors of CVD at baseline, a multivariate Cox regression risk model was established and a nomogram was developed. …”
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    Construction of a risk assessment model of cardiovascular disease in a rural Chinese hypertensive population based on lasso‐Cox analysis
  5. 1325
    “…Western blot also verified that carfilzomib promoted STAT1 inhibition and subsequently inhibited COX-2 and iNOS. CONCLUSIONS: Inhibition of the STAT1/COX-2/iNOS signaling pathway by carfilzomib not only inhibited MM cell proliferation, but was also an important mechanism of inducing MM cell apoptosis.…”
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    Carfilzomib inhibits the proliferation and apoptosis of multiple myeloma cells by inhibiting STAT1/COX-2/iNOS signaling pathway
  6. 1326
    “…An animal AS model was established to confirm the role of DANCR/microR-214-5p/COX20 (the chaperone of cytochrome c oxidase subunit II COX2) in AS development. …”
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    The lncRNA DANCR promotes development of atherosclerosis by regulating the miR-214-5p/COX20 signaling pathway
  7. 1327
    “…Survival-related genes were identified by gene set enrichment analysis (GSEA) and univariate Cox. Then, we applied a Bayesian hierarchical lasso Cox model for prognostic signature screening. …”
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    Bayesian hierarchical lasso Cox model: A 9-gene prognostic signature for overall survival in gastric cancer in an Asian population
  8. 1328
    “…Docking values obtained from distachionate-COX-2 complex suggest a potent inhibitor evaluated for this protein. …”
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    A Novel Distachionate from Breynia distachia Treats Inflammations by Modulating COX-2 and Inflammatory Cytokines in Rat Liver Tissue
  9. 1329
    “…Protein expression of the MEK-ERK-COX-2 pathway was also examined by western blotting to elucidate the mechanism underlying particle-induced anti-inflammatory effects. …”
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    ZnO nanoparticles attenuate polymer-wear-particle induced inflammatory osteolysis by regulating the MEK-ERK-COX-2 axis
  10. 1330
    “…MATERIALS AND METHODS: Longitudinal record analysis (cohort approach) of 640 regular AME attendees between 2010 and 2014 was performed to estimate incidence and incidence rates. Cox regression was conducted to estimate the risk for hypertension in the study period. …”
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    Incidence and Risk for Hypertension among Regular Medical Examination Attendee Cohort in an Automobile Industry. A Cox- Regression Analysis Model
  11. 1331
    “…Cyclooxygenase-2 (COX-2) plays a critical role in regulating innate immunity and metabolism by producing prostaglandins (PGs) and other lipid mediators. …”
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    COX-2 Deficiency Promotes White Adipogenesis via PGE2-Mediated Paracrine Mechanism and Exacerbates Diet-Induced Obesity
  12. 1332
    “…Therefore, the study was designed to delineate the health problems among FDMNs admitted to Cox's Bazar Medical College Hospital. METHODS: This hospital-based cross-sectional study was conducted at the Medicine ward, Cox's Bazar Medical College Hospital, for a six-month period following approval. …”
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    Health problems among Forcibly Displaced Myanmar Nationals (FDMNs) admitted to the Medicine ward of Cox's Bazar Medical College Hospital
  13. 1333
    por Wang, Yun, Lu, Ting
    Publicado 2022
    “…Clustered care is a combination of evidence-based linked interventions and a multidisciplinary team providing the best possible care through evidence-based research and highly operational practice, and it can improve outcomes for ischemic stroke patients more than implementation alone. This paper presents a Cox proportional risk regression-based model, using it to build the most used semi-parametric model for multifactorial survival analysis, due to its advantages of both parametric and nonparametric models, and to analyze the factors influencing survival time in study subjects with incomplete data. …”
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    Prediction of Ischemic Stroke Recurrence Based on COX Proportional Risk Regression Model and Evaluation of the Effectiveness of Patient Intensive Care Interventions
  14. 1334
    “…Cox7b is not an easy therapeutic target and is most probably not unique in driving brain metastasis. …”
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    Mitochondrial Protein Cox7b Is a Metabolic Sensor Driving Brain-Specific Metastasis of Human Breast Cancer Cells
  15. 1335
    “…A 1.4-Mb genomic deletion extending from intron 5 of COX10 to PMP22 was detected. DISCUSSION: These findings suggest that in this family, Leigh syndrome is associated with a mitochondrial respiratory chain complex IV deficiency caused by biallelic COX10 mutations coexisting with HNPP caused by heterozygous PMP22 deletion.…”
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    Biallelic COX10 Mutations and PMP22 Deletion in a Family With Leigh Syndrome and Hereditary Neuropathy With Liability to Pressure Palsy
  16. 1336
    “…AIM: Cyclooxygenase‐2 (COX‐2) activity protects against oxidative stress and apoptosis early in experimental kidney injury. …”
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    Increased COX‐2 after ureter obstruction attenuates fibrosis and is associated with EP(2) receptor upregulation in mouse and human kidney
  17. 1337
    “…However, two transcripts encoding for COX1 and ND6 terminate in the non-conventional AGA or AGG codon, respectively. …”
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    Human mtRF1 terminates COX1 translation and its ablation induces mitochondrial ribosome-associated quality control
  18. 1338
    “…Molecular identification of parasites was conducted through sequencing of the mitochondrial cytochrome c oxidase subunit 1 (cox1) gene. The fish hosts in the present study were also barcoded (mitochondrial cox1 gene) to confirm specific identities. …”
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    Molecular (cox1), geographical, and host record investigation of monogeneans Mazocraes australis (Mazocraeidae), Polylabris sillaginae, and P. australiensis (Microcotylidae)
  19. 1339
    “…Our earlier work demonstrated immunosuppressive effects of NOS2 and COX2 tumor expression. Here, we show that NOS2/COX2 levels influence both the polarization and spatial location of lymphoid cells including CD8(+) T cells. …”
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    Systemic Nos2 Depletion and Cox inhibition limits TNBC disease progression and alters lymphoid cell spatial orientation and density
  20. 1340
    por Poon, Victor, Lu, Dan
    Publicado 2022
    “…A Cox proportional hazard (CoxPH) model is conventionally used to assess exposure–response (E–R), but its performance to uncover the ground truth when only one dose level of data is available has not been systematically evaluated. …”
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    Performance of Cox proportional hazard models on recovering the ground truth of confounded exposure–response relationships for large‐molecule oncology drugs
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