A reversible SRC-relayed COX2 inflammatory program drives resistance to BRAF and EGFR inhibition in BRAF(V600E) colorectal tumors

por Ruiz-Saenz, Ana, Atreya, Chloe E., Wang, Changjun, Pan, Bo, Dreyer, Courtney A., Brunen, Diede, Prahallad, Anirudh, Muñoz, Denise P., Ramms, Dana J., Burghi, Valeria, Spassov, Danislav S., Fewings, Eleanor, Hwang, Yeonjoo C., Cowdrey, Cynthia, Moelders, Christina, Schwarzer, Cecilia, Wolf, Denise M., Hann, Byron, VandenBerg, Scott R., Shokat, Kevan, Moasser, Mark M., Bernards, René, Gutkind, J. Silvio, van ‘t Veer, Laura J., Coppé, Jean-Philippe
Publicado 2023

Comparison of a chronic kidney disease predictive model for type 2 diabetes mellitus in Malaysia using Cox regression versus machine learning approach

por Sim, Ruth, Chong, Chun Wie, Loganadan, Navin Kumar, Adam, Noor Lita, Hussein, Zanariah, Lee, Shaun Wen Huey
Publicado 2022

A comparison of machine learning models and Cox proportional hazards models regarding their ability to predict the risk of gastrointestinal cancer based on metabolic syndrome and its components

por Tran, Tao Thi, Lee, Jeonghee, Gunathilake, Madhawa, Kim, Junetae, Kim, Sun-Young, Cho, Hyunsoon, Kim, Jeongseon
Publicado 2023

Differential Effects of Iron Chelates vs. Iron Salts on Induction of Pro-Oncogenic Amphiregulin and Pro-Inflammatory COX-2 in Human Intestinal Adenocarcinoma Cell Lines

por Tarczykowska, Agata, Engström, Niklas, Dobermann, Darja, Powell, Jonathan, Scheers, Nathalie
Publicado 2023

Reprogramming of Mitochondrial Respiratory Chain Complex by Targeting SIRT3‐COX4I2 Axis Attenuates Osteoarthritis Progression (Adv. Sci. 10/2023)

por Zhang, Yijian, Liu, Yang, Hou, Mingzhuang, Xia, Xiaowei, Liu, Junlin, Xu, Yong, Shi, Qin, Zhang, Zhongmin, Wang, Liang, Shen, Yifan, Yang, Huilin, He, Fan, Zhu, Xuesong
Publicado 2023

Ge-Gen Decoction Exerts an Anti-Primary Dysmenorrhea Effect in Rats by Inactivating the HSP90/NLRP3/NF-κB/COX-2 Pathway

por Xie, Yazhen, Qian, Jianqiang
Publicado 2023

TNF-α/IL-1β-licensed hADSCs alleviate cholestatic liver injury and fibrosis in mice via COX-2/PGE2 pathway

por Luan, Xiaoyu, Chen, Peng, Li, Yaxin, Yuan, Xinying, Miao, Longyu, Zhang, Pengyu, Cao, Qilong, Song, Xiaomin, Di, Guohu
Publicado 2023

Therapeutic Effects of Combined Treatment with the AEA Hydrolysis Inhibitor PF04457845 and the Substrate Selective COX-2 Inhibitor LM4131 in the Mouse Model of Neuropathic Pain

por Wen, Jie, Sackett, Scott, Tanaka, Mikiei, Zhang, Yumin
Publicado 2023

Shc3 facilitates breast cancer drug resistance by interacting with ErbB2 to initiate ErbB2/COX2/MDR1 axis

por Liu, Yun, Cao, Fang, Xia, Fantong, Li, Jie, Dong, Xiaobao, Guo, Yan, Zhang, Jun, Zhao, Qiang, Liu, Yuanyuan
Publicado 2023

RNA-Seq Reveals Sex Differences in Gene Expression during Peripheral Neuropathic Inflammation and in Pain Relief from a COX-2 Inhibiting Theranostic Nanoemulsion

por Deal, Brooke, Phillips, Katherine, Crelli, Caitlin, Janjic, Jelena M., Pollock, John A.
Publicado 2023

Meloxicam Targets COX-2/NOX1/NOX4/Nrf2 Axis to Ameliorate the Depression-like Neuropathology Induced by Chronic Restraint Stress in Rats

por Arab, Hany H., Khames, Ali, Mohammad, Mostafa K., Alsufyani, Shuruq E., Ashour, Ahmed M., El-Sheikh, Azza A. K., Darwish, Hany W., Gad, Amany M.
Publicado 2023

Time to Viral Re-suppression and Its Predictors among Adults on Second-Line Antiretroviral Therapy in South Wollo Zone Public Hospitals: Stratified Cox Model

por Melak, Dagnachew, Wedajo, Shambel, Dewau, Reta
Publicado 2023

Natural fulvic acids inhibit non-small-cell lung cancer through the COX-2/PGE2/EP4 axis: In silico and in vivo assessments

por Xin, Pengfei, Wang, Shirui, Xu, Xin, Liu, Qingmei, Zhang, Caifeng
Publicado 2023

Herbal melanin modulates PGE2 and IL-6 gastroprotective markers through COX-2 and TLR4 signaling in the gastric cancer cell line AGS

por El-Obeid, Adila, Maashi, Yahya, AlRoshody, Rehab, Alatar, Ghada, Aljudayi, Modhi, Al-Eidi, Hamad, AlGaith, Nouf, Khan, Altaf Husain, Hassib, Adil, Matou-Nasri, Sabine
Publicado 2023