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  1. 1961
    “…According to the results, IATL inhibited IKKβ phosphorylation, thus inhibiting both the binding of NF‐κB to the cyclooxygenase 2 (COX‐2) promoter and the recruitment of p300 and eventually inhibiting COX‐2 expression. …”
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  2. 1962
  3. 1963
    “…From the lncRNAs identified in these preserved modules, prognostic lncRNAs were selected using univariate Cox regression analysis in combination with the L1-penalized (LASSO) Cox-proportional Hazards (Cox-PH) model. …”
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  4. 1964
    “…The current study aimed to identify the radiosensitizing effect of celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, in combination with radiotherapy in non-small-cell lung cancer (NSCLC) cells. …”
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  5. 1965
  6. 1966
  7. 1967
  8. 1968
    “…Cyclic imides bearing 3-benzenesulfonamide (2–5, and 9), acetophenone oxime (11–14, 18, and 19) exhibited high selectivity against COX-2 with SI > 55.6–333.3 relative to that for celecoxib [SI > 387.6]. β-Phenylalanine derivatives 21–24 and 28 were non-selective towards COX-1/2 isozymes as indicated by their SI of 0.46–0.68.…”
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  9. 1969
    por Kim, Donghee, Kim, Hyo-Jin, Jun, Hee-Sook
    Publicado 2020
    “…PME treatment increased the level of phosphorylated p38 mitogen-activated protein kinase (MAPK), and pretreatment with SB 203580, a p38 MAPK inhibitor, significantly suppressed this PME-induced increase in the expression of COX2 and melanogenic genes. These results indicate that PME induced the expression of melanogenic genes by inducing COX2 expression via the activation of the p38 MAPK pathway, thereby contributing to the enhancement of melanogenesis.…”
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  10. 1970
    “…The pro-inflammatory cytokine interleukin 1β (IL-1β) induces the synthesis of prostaglandin E(2) by upregulating cyclooxygenase-2 (COX-2) in the synovial tissue of individuals with autoimmune diseases, such as rheumatoid arthritis (RA). …”
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  11. 1971
  12. 1972
  13. 1973
    “…Two partial cox1 sequences were obtained; they were identified as S. cruzi and deposited in the GenBank™ database under the accession numbers MW490605 and MW490606. …”
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  14. 1974
    “…In conclusion, our results established a MALAT1/miR-146a/COX2 signaling axis. The overexpression of MALAT1 could increase the expression of COX2 by inhibiting the expression of miR-146a, thus affecting the pulmonary function of COPD patients.…”
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  15. 1975
    “…CONCLUSION: A mouthwash containing 1% of chitosan could suppress the expression of inflammatory mediators IL-1β, COX-2, and iNOS.…”
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  16. 1976
  17. 1977
  18. 1978
    “…The inflammation of the airway and lung could be triggered by upregulation cyclooxygenase (COX)-2 and prostaglandin E(2) (PGE(2)) induced by various proinflammatory factors. …”
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  19. 1979
  20. 1980
    por Legesse, Alemayehu
    Publicado 2022
    “…Descriptive statistics were used to summarize the study variables. The standard Cox-proportional hazards model and a shared lognormal frailty model have been compared. …”
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