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  1. 4581
    “…Metastatic melanoma develops once transformed melanocytic cells begin to de-differentiate into migratory and invasive melanoma cells with neural crest cell (NCC)-like and epithelial-to-mesenchymal transition (EMT)-like features. …”
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    An epigenetic switch controls an alternative NR2F2 isoform that unleashes a metastatic program in melanoma
  2. 4582
    por Li, Qing, Chen, Jieyi, Faux, Pierre, Delgado, Miguel Eduardo, Bonfante, Betty, Fuentes-Guajardo, Macarena, Mendoza-Revilla, Javier, Chacón-Duque, J. Camilo, Hurtado, Malena, Villegas, Valeria, Granja, Vanessa, Jaramillo, Claudia, Arias, William, Barquera, Rodrigo, Everardo-Martínez, Paola, Sánchez-Quinto, Mirsha, Gómez-Valdés, Jorge, Villamil-Ramírez, Hugo, Silva de Cerqueira, Caio C., Hünemeier, Tábita, Ramallo, Virginia, Wu, Sijie, Du, Siyuan, Giardina, Andrea, Paria, Soumya Subhra, Khokan, Mahfuzur Rahman, Gonzalez-José, Rolando, Schüler-Faccini, Lavinia, Bortolini, Maria-Cátira, Acuña-Alonzo, Victor, Canizales-Quinteros, Samuel, Gallo, Carla, Poletti, Giovanni, Rojas, Winston, Rothhammer, Francisco, Navarro, Nicolas, Wang, Sijia, Adhikari, Kaustubh, Ruiz-Linares, Andrés
    Publicado 2023
    “…Novel regions include candidate genes and genome regulatory elements previously implicated in craniofacial development, and show preferential transcription in cranial neural crest cells. The automated approach used here should simplify the collection of large study samples from across the world, facilitating a cosmopolitan characterization of the genetics of facial features.…”
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    Automatic landmarking identifies new loci associated with face morphology and implicates Neanderthal introgression in human nasal shape
  3. 4583
    “…The focused question was, “For patients (P) treated with external connection (I) or Morse taper (C) dental implants, were there differences in the marginal bone crest maintenance after at least three months in occlusal function (O)”? …”
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    Marginal Bone Level and Clinical Parameter Analysis Comparing External Hexagon and Morse Taper Implants: A Systematic Review and Meta-Analysis
  4. 4584
    “…Next, we revealed that STRA6-knockout human embryonic stem cells (hESCs) could differentiate into cardiomyocytes similarly to wild-type hESCs, but could not differentiate properly into mesodermal nor neural crest cell-derived smooth muscle cells (SMCs) in vitro. …”
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    STRA6 is essential for induction of vascular smooth muscle lineages in human embryonic cardiac outflow tract development
  5. 4585
    “…Indeed, STORM analysis showed that parthenolide increased Nav1.5 cluster density at both the lateral membrane (crest) and intercalated disc region in mdx CMs while it had no effect on WT CMs. …”
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    Decreasing microtubule detyrosination by parthenolide restores sodium current in mdx cardiomyocytes
  6. 4586
    “…BACKGROUND: Accumulating evidence suggests that the maxillary process, to which cranial crest cells migrate, is essential to tooth development. …”
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    Single cell RNA sequencing reveals mesenchymal heterogeneity and critical functions of Cd271 in tooth development
  7. 4587
    “…To better understand the diversity and distribution of Antarctic terrestrial algae, we performed a pilot study on the surface soils of Meseta, an ice-free plateau mountain crest of Fildes Peninsula, King George Island, being hardly influenced by the marine realm and anthropogenic disturbances. …”
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    Unrecognized diversity and distribution of soil algae from Maritime Antarctica (Fildes Peninsula, King George Island)
  8. 4588
    “…CONTEXT: Rapid-onset obesity with central hypoventilation, hypothalamic dysfunction, and autonomic dysregulation with neural crest tumors (ROHHAD-NET) syndrome pathophysiology remains elusive. …”
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    Blood Lymphocyte Subsets and Proinflammatory Cytokine Profile in ROHHAD(NET) and non-ROHHAD(NET) Obese Individuals
  9. 4589
    “…We also demonstrate that the SMIs produce dose-dependent ectopic mineralization in vivo in rats as well as significantly increase posterolateral spine fusion rates in rabbits in vivo, both as standalone osteogenic drugs and in combination with autologous iliac crest bone graft. CONCLUSIONS: Few if any osteogenic small molecules possess the osteoinductive potency of BMP itself – that is, the ability to form de novo ectopic bone as a standalone agent. …”
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    Sclerostin small-molecule inhibitors promote osteogenesis by activating canonical Wnt and BMP pathways
  10. 4590
    “…RESULTS: We demonstrate that the emergent dynamics of our regulatory network comprising MITF, SOX10, SOX9, JUN and ZEB1 can recapitulate experimental observations about the co-existence of diverse phenotypes (proliferative, neural crest-like, invasive) and reversible cell-state transitions among them, including in response to targeted therapy and immune checkpoint inhibitors. …”
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    Dynamical modeling of proliferative-invasive plasticity and IFNγ signaling in melanoma reveals mechanisms of PD-L1 expression heterogeneity
  11. 4591
    “…FUNDING: This research was supported by ARIM JAPAN of 10.13039/501100001700MEXT, the Program for Developing Next-generation Researchers (10.13039/501100002241Japan Science and Technology Agency), 10.13039/501100001691KAKEN (18K15923, 21K07217) (JSPS), 10.13039/501100003382CREST (JPMJCR19H2, JST), and FOREST-Souhatsu (JST). 10.13039/501100005865Mochida Memorial Foundation for Medical and Pharmaceutical Research; 10.13039/100007449Takeda Science Foundation; The Japan Health Foundation; and 10.13039/501100008886Princess Takamatsu Cancer Research Fund. …”
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    Contrast-enhanced ultrasound imaging for monitoring the efficacy of near-infrared photoimmunotherapy
  12. 4592
    “…Meta-analyses and sub-group analyses were performed to assess the effect of MSC-EVs on Bone Volume/Total Volume (BV/TV) or the distance between the cementoenamel junction and alveolar bone crest (CEJ-ABC) in pre-clinical animal models of periodontitis. …”
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    Mesenchymal stem cell-derived extracellular vesicles for treatment of bone loss within periodontitis in pre-clinical animal models: a meta-analysis
  13. 4593
    por Samuel, Kelara
    Publicado 2023
    “…Yang MD, Sarimar Agosto-Salgado MD Background: Paragangliomas are neuroendocrine tumors arising from neural crest chromaffin cells of the autonomic ganglia and can be parasympathetic or sympathetic in nature. …”
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    SAT547 Hereditary Paraganglioma: The Rare Co-Existence Of Two Genetic Syndromes Associated With PPGL-pheochromocytoma
  14. 4594
    “…In addition, gender, age, Angle classification, MARPE duration, midpalatal suture maturation stage, maximal central diastema (MCD) immediately after expansion, crown width to length ratio (W/L), pretreatment overlap of maxillary central incisors, and the distance between the approximal contact point of the central incisors and the bone crest (CP-B) were also record. RESULTS: Twenty-two patients were included (2 men, 20 women, mean age 27.3 ± 8.8 years) and 4 patients (18%) showed a significant reduction in the Jemt score following MARPE (p = 0.04), indicating papilla recession. …”
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    Influence of miniscrew-assisted rapid palatal expansion (MARPE) on the interdental papilla height of maxillary central incisors
  15. 4595
    “…This technique aims to improve bone quality all around the implants at both the crest and apex locations. In some clinical scenarios, insufficient horizontal bone with less than 3 mm prevents implant placement. …”
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    A Modified Ridge-Splitting Technique to Restore a Completely Edentulous Maxillary Arch With a Cement-Retained Implant Prosthesis
  16. 4596
    “…We previously demonstrated that JAG1 induces murine cranial neural crest (CNC) cells towards osteoblast commitment via a NOTCH non-canonical pathway involving JAK2-STAT5 (1) and that JAG1 delivery with CNC cells elicits bone regeneration in vivo. …”
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    Delivery of A Jagged1-PEG-MAL hydrogel with Pediatric Human Bone Cells Regenerates Critically-Sized Craniofacial Bone Defects
  17. 4597
    “…The UVB group’s mitochondrial volume was reduced, the membrane density increased, and the mitochondrial crest decreased or even disappeared. GPX4 and FSP1 expression levels were similarly found to be lower in the UVB group. …”
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    Variation of Ferroptosis-Related Markers in HaCaT Cell Photoaging Models Induced by UVB
  18. 4598
    “…Probing depth (PD), gingival recession (GR), clinical attachment level (CAL), as well as the distance between bone crest (BC) level and base of the defect (BD) (intrabony defect depth, IBD) were evaluated at baseline and 1 year after treatment. …”
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    A novel periodontal endoscopy-aided non-incisional periodontal regeneration technique in the treatment of intrabony defects: a retrospective cohort study
  19. 4599
    “…BACKGROUND: Craniofacial birth defects result from defects in cranial neural crest (NC) patterning and morphogenesis. The vertebrate craniofacial skeleton is derived from cranial NC cells and the patterning of these cells occurs within the pharyngeal arches. …”
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    A zebrafish screen for craniofacial mutants identifies wdr68 as a highly conserved gene required for endothelin-1 expression
  20. 4600
    “…We therefore assessed PIK3CA for mutation in human neuroblastomas, as well as in neuroblastomas arising in transgenic mice with MYCN overexpressed in neural-crest tissues. In this murine model we additionally surveyed for Ras family and Braf mutations as these have not been previously reported. …”
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    Mutations in PIK3CA are infrequent in neuroblastoma
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