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Mostrando 1 - 20 Resultados de 390 Para Buscar '"Crims"', tiempo de consulta: 0.51s Limitar resultados
  1. 1
    por Calders, Pere, 1912-
    Publicado 1995
    Libro
    Un crim : i altres contes /
  2. 2
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    Crim1 suppresses left ventricular hypertrophy
  3. 3
    “…Our results showed that hormones and IFN-τ increased the expression of CRIM1 in goat endometrial epithelial cells (EECs). …”
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    Essential Role of CRIM1 on Endometrial Receptivity in Goat
  4. 4
    “…Using this and two other mutant alleles, Crim1(null) and Crim1(cko), we show that the lens defects in Crim1 mouse mutants originate from defective LE cell polarity, proliferation and cell adhesion. …”
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    Crim1 regulates integrin signaling in murine lens development
  5. 5
    “…CircCRIM1 positively affected the expression of CRIM1. …”
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    CircCRIM1 promotes ovarian cancer progression by working as ceRNAs of CRIM1 and targeting miR-383-5p/ZEB2 axis
  6. 6
    “…Western blot analysis of cultured skin fibroblast lysates has been the gold standard for determining CRIM status. Here, we evaluated CRIM status using peripheral blood mononuclear cell (PBMC) protein. …”
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    Clinical laboratory experience of blood CRIM testing in infantile Pompe disease
  7. 7
    “…Background. CRIM1 is a plasma membrane bound protein containing six cysteine-rich repeats (CRR). …”
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    CRIM1 is localized to the podocyte filtration slit diaphragm of the adult human kidney
  8. 8
    “…BACKGROUND: CRIM1 is involved in the development and preservation of the nervous system, capillary development, and vascular maintenance. …”
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    Low CRIM1 Levels Predict Poor Prognosis in Breast Cancer Patients
  9. 9
    “…Collectively, our data demonstrates that Crim1 is essential for cell-autonomous and paracrine aspects of heart development.…”
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    Crim1 has cell-autonomous and paracrine roles during embryonic heart development
  10. 10
    “…However, the majority of cross reactive immunologic material (CRIM)-negative (CN) patients have immune responses with significant clinical decline despite continued ERT. …”
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    CRIM-negative infantile Pompe disease: Characterization of immune responses in patients treated with ERT monotherapy
  11. 11
    “…To our knowledge, this is the first report of successful early ERT and ITI in a prenatally diagnosed CRIM-negative IPD patient and the youngest IPD patient to receive ITI safely. …”
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    A Race Against Time—Changing the Natural History of CRIM Negative Infantile Pompe Disease
  12. 12
    “…The CRIM1 knockdown phenotype was, in some cases, mild and resulted in perturbed neural fold morphogenesis. …”
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    CRIM1 Complexes with ß-catenin and Cadherins, Stabilizes Cell-Cell Junctions and Is Critical for Neural Morphogenesis
  13. 13
    “…We report the clinical outcome of our Dutch infants in relation to their CRIM status and immune response. METHODS: Eleven patients were genotyped and their CRIM status was determined. …”
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    Enzyme therapy and immune response in relation to CRIM status: the Dutch experience in classic infantile Pompe disease
  14. 14
    “…The target prediction and luciferase reporter assays were performed to confirm the binding between miR-665 and 3ʹ-UTR of the CRIM1 gene. In addition, rescue assays were used to determine whether CRIM1 upregulation abolished the inhibitory effect of miR-665. …”
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    miR-665 Suppresses the Epithelial–Mesenchymal Transition and Progression of Gastric Cancer by Targeting CRIM1
  15. 15
    “…OBJECTIVE(S): Angiotensin II (Ang II) plays a key role in the regulation of myocardial hypertrophy via downstream cysteine-rich transmembrane bone morphogenetic protein regulator 1 (Crim1). However, it is still unclear whether Crim1 is involved in ionic channel remodeling. …”
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    Crim1 inhibits angiotensin II-induced hypertrophy and preserves Kv4.2 expression in cardiomyocytes
  16. 16
    “…Mechanistically, circCRIM1 destabilized HLA-F mRNA via competitive binding to IGF2BP1. …”
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    Silencing of circCRIM1 Drives IGF2BP1-Mediated NSCLC Immune Evasion
  17. 17
    “…Based on known Vegfa binding by Crim1 and Crim1 expression in retinal vasculature, where angiogenesis is known to be Vegfa dependent, we tested the hypothesis that Crim1 is involved in the regulation of Vegfa signaling. …”
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    Crim1 maintains retinal vascular stability during development by regulating endothelial cell Vegfa autocrine signaling
  18. 18
    “…The implementation of such a Learning Healthcare System needs an information model for clinical research (CRIM), as an informational backbone to integrate aspects of primary care with clinical trials and database searches. …”
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    Extension of the primary care research object model (PCROM) as clinical research information model (CRIM) for the “learning healthcare system”
  19. 19
    “…CONCLUSIONS: The CRIM1 rs3821169 variant is suggested to be an independent and/or additive genetic determinant of thiopurine toxicity beyond NUDT15 and TPMT in pediatric ALL.…”
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    Homozygote CRIM1 variant is associated with thiopurine-induced neutropenia in leukemic patients with both wildtype NUDT15 and TPMT
  20. 20
    “…Enzyme replacement therapy (ERT) with rhGAA has improved clinical outcomes in infantile Pompe disease (IPD). A subset of CRIM-positive IPD patients develop high and sustained antibody titers (HSAT; ≥51,200) and/or sustained intermediate titer (SIT; ≥12,800 and <51,200), similar to CRIM-negative patients. …”
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    Online Artículo Texto
    Characterization of immune response in Cross-Reactive Immunological Material (CRIM)-positive infantile Pompe disease patients treated with enzyme replacement therapy
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