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41“…In genetic crosses, ORA59OE rap2.3 crossed lines lost ORA59-mediated positive effects and behaved like rap2.3 mutant. …”
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42por Graham, Jessica B., Swarts, Jessica L., Edwards, Kristina R., Voss, Kathleen M., Green, Richard, Jeng, Sophia, Miller, Darla R., Mooney, Michael A., McWeeney, Shannon K., Ferris, Martin T., Pardo-Manuel de Villena, Fernando, Gale, Michael, Lund, Jennifer M.“…We identified collaborative cross lines with extreme Treg abundance at steady state, either high or low, and used mice with these extreme phenotypes to demonstrate that baseline Treg quantity predicted the magnitude of the CD8 T cell response to WNV infection, although higher numbers of baseline Tregs were associated with reduced CD8 T cell functionality in terms of TNF and granzyme B expression. …”
Publicado 2021
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43PD-1 inhibitor treatment in a penile cancer patient with MMR/MSI status heterogeneity: A case reportpor Du, YunYi, Zhang, XiaoLing, Zhang, Ying, Li, WeiLing, Hu, WenQing, Zong, Liang, Zhao, Jun“…Due to oligometastatic lesion progression caused only by the heterogeneity of MMR/MSI status, PD1 inhibitor cross-line therapy can also be considered an appropriate treatment.…”
Publicado 2022
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44“…METHODS: We included 158 patients with chronic liver disease, who underwent 2-D SWE examination by a novice and an expert. A cross line at the center of the elastogram was drawn and was divided it into four locations: top-left, top-right, bottom-left, and bottom-right. …”
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45por Bottomly, Daniel, Ferris, Martin T., Aicher, Lauri D., Rosenzweig, Elizabeth, Whitmore, Alan, Aylor, David L., Haagmans, Bart L., Gralinski, Lisa E., Bradel-Tretheway, Birgit G., Bryan, Janine T., Threadgill, David W., de Villena, Fernando Pardo-Manuel, Baric, Ralph S., Katze, Michael G., Heise, Mark, McWeeney, Shannon K.“…Here we used mice from 44 influenza-infected pre-Collaborative Cross lines determined to have extreme phenotypes with regard to the host response to influenza A virus infection. …”
Publicado 2012
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46“…The QTL on chromosome I with the highest LOD score was confirmed and narrowed down to a 500 gene interval in an advanced population derived from one of the back-cross lines. Our results provide the foundation for the genetic dissection of type VI trichome morphology and the introgression of these trichome traits into cultivated tomato lines for increased insect resistance. …”
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47por Shoja, Maryam, Mehri, Soghra, Amin, Bahareh, Askari, Vahid Reza, Hosseinzadeh, Hossein“…RESULTS: Both extracts and crocin increased the number of crossed lined in the open field test. PTZ kindling seizure was inhibited in animals received extract (80 and 160 mg/kg) in both regimens. …”
Publicado 2018
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48por Murali, Gunasekaran, Abid, Sallal Rashid, Amran, Mugahed, Vatin, Nikolai Ivanovich, Fediuk, Roman“…The findings indicated that the line notched specimens and sand bedding significantly decreased the coefficient of variation (COV) of the test results suggesting some alterations. Using a cross-line notched specimen and line of impact with coarse bedding also effectively reduced COV for all mixtures.…”
Publicado 2022
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49por Alsarani, Majed M., Alsadon, Omar, Alageel, Omar, Alfrisany, Najm, Almutairi, Zeyad, Al-Gawati, Mahmoud A., Almozainy, Mayyadah“…A set of fifteen rectangular ZrO(2) blocks were randomly divided into five groups according to surface pretreatment: Control G(0)—no treatment; G(1)—TBC with silane application; G(2)—femtosecond laser irradiation with horizontal lines 30 µm apart; (G3)—femtosecond laser irradiation with horizontal lines 15 µm apart; and G(4)—femtosecond laser irradiation with cross lines 30 µm apart. The pretreated surfaces were characterized by a surface profilometer, tensiometer and scanning electron microscope. …”
Publicado 2023
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50“…It is suitable for QTL mapping on any mouse populations, including the incipient Collaborative Cross lines. Applied HTreeQA, significant QTLs are found for two phenotypes of the PreCC lines, white head spot and running distance at day 5/6. …”
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51“…A structural analysis of the inner and outer retinal layers at the macula in the RP group was also performed using the HD cross-line protocol. RESULTS: The RP group comprised six eyes of six RP subjects and control group comprised six eyes of six control subjects. …”
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52“…Materials and methods: A total of 67 eyes of 48 individuals were scanned using an optovue Mode RT100 version 2.0 OCT machine. Cross-line CAM-L scans were taken and the com bined bulbar conjunctival and Tenon's layer thickness was measured 3 mm above the superior limbus. …”
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53por Verfaille, Charlotte, Filbrich, Lieve, Cordova Bulens, David, Lefèvre, Philippe, Berquin, Anne, Barbier, Olivier, Libouton, Xavier, Fraselle, Virginie, Mouraux, Dominique, Legrain, Valéry“…By means of a robotic handle placed below the screen, they were asked to move a cursor, to reach and cross lines at their estimated midpoint. In some of the stimulation series, the affected hand was placed below the mirror so that some lines appeared projected onto that hand. …”
Publicado 2019
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54por Lu, Yuzhu, Meng, Yunlong, Zeng, Jia, Luo, Ying, Feng, Zhen, Bian, Liying, Gao, Suyun“…Overexpression of OsGIF1 did not exhibit new phenotype while knockdown lines displayed pleiotropic growth defects including shrunken leaves. The crossed lines of mOsGRF1 overexpression and OsGIF1 knockdown still exhibited shrunk leaves, indicating that OsGIF1 is indispensable in leaf growth regulated by OsGRF1. …”
Publicado 2020
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55por Pathak, Pushpraj K., Vashisht, S.K., Baby, S., Jithin, P.K., Jain, Y., Mahawar, R., Sharan, V.G. G.K.“…All relative measurements (PDDs, in-line, cross-line and angular profiles) were performed with 0.0125 cc point chamber. …”
Publicado 2021
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56“…The forest plots illustrated the point and pooled estimates with 95% confidence intervals (crossed lines). All statistical analyses were performed using Comprehensive meta-Analysis V.2 software. …”
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57“…Significantly decreased locomotion and behaviors were also observed in the hole crossing, line crossing, head dipping, grooming, rearing, stretch attend, central square entry, central square duration, defecation, and urination, in a dose-dependent manner (p < 0.01). …”
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58por Inoda, Satoru, Takahashi, Hidenori, Arai, Yusuke, Tampo, Hironobu, Matsui, Yoshitsugu, Kawashima, Hidetoshi, Yanagi, Yasuo“…For each eye, one horizontal and one vertical OCT scan in cross-line mode were used. The GoogLeNet architecture was implemented. …”
Publicado 2023
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59por Zhang, Cui, Xu, Yunyuan, Guo, Siyi, Zhu, Jiaying, Huan, Qing, Liu, Huanhuan, Wang, Lei, Luo, Guanzheng, Wang, Xiujie, Chong, Kang“…Phenotypic analysis of the crossed lines depleted in both LIC and BZR1 suggested that BZR1 functionally depends on LIC. …”
Publicado 2012
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60por Xie, Yizhao, Ge, Rui, Sang, Die, Luo, Ting, Li, Wei, Ji, Xuening, Yuan, Peng, Wang, Biyun“…Moreover, evidence of cross‐line use of lapatinib was provided.…”
Publicado 2020
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