“…Inoculation with NC1 (iv and sc) lead to foetal deaths in all group 1 dams (6/6) and in 3/6 group 2 dams from day 28pi; statistically significant (p ≤ 0.05) increases in cell-mediated immune (CMI) responses including antigen-specific cell proliferation and IFN-γ production as well as increased levels of IL-4, IL-10 and IL-12 were observed in challenged dams compared to the group 3 animals. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Decision Analytic Models (DAMs) are established means of evidence-synthesis to differentiate between health interventions. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The body mass (BM) gain was 50% greater before pregnancy and 80% greater during pregnancy in HF dams than SC dams. Dams fed an HF diet showed higher oral glucose tolerance test (OGTT), blood pressure, serum corticosterone, and insulin levels than dams fed SC. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…F1 mice from dams on the MS diet exhibited increased global T cell DNA methylation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Serum 5-HT was increased in the 5-HTP fed dams beginning on d20 of gestation and remained elevated through d9, while it was only increased on d9 in the L-TRP fed dams. 5-HT levels were increased in mammary gland and liver of both groups. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Foetuses from infected dams mounted Neospora-specific humoral and cell-mediated immune (CMI) responses by 14 dpi. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We also found that the Nrf2 expression both in mRNA and protein levels were up-regulated in the ZEN-treated groups of pregnant dams and the high-dose of ZEN group of weaned dams. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Fertility after insemination was higher for L + ewes than for ++ ewes. Lambs from ++ dams were heavier (+300 g) than the lambs of L + dams and the mortality of twin lambs born from ++ dams was lower than those from L + dams. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In contrast, the LowLA diet reduced BM LA content by about 50 % compared with the CTRL diet at PN7. BM of dams fed the n-3LCP or n-3LCP/MCFA diet contained about 6-fold more n-3 LCP than BM of the dams fed the CTRL diet at PN7. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Although the reproductive strategy of dams resulted in greater predation of fawns from alternative predators, it likely improved the life-long reproductive success of dams, as many were late-aged (>10 years old) and could have produced multiple litters of fawns. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We found that calorie-restricted dams tended to have a reduced litter size, although the offspring showed normal weight at birth. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…However, dams and offsprings of the GBR and OE groups had higher hepatic H3 acetylation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Progeny were weaned on postnatal day (PND) 21 to the same diet as their dams and were fed this diet until termination of the experiment at PND 138. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Dams were fed 2AA contaminated diet during the period of gestation and postpartum. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Dams on BCAA‐supplemented diets exhibited increased PPD/A‐like behavior, decreased dopaminergic function, and decreased plasma tyrosine and histidine levels when assessed on postnatal day (P)8. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: The genomic design increased genetic gain by 26% when the reference population was based on sire medium-density genotypes and by 54% when the reference population included both sire and dam medium-density genotypes. When medium-density genotypes of male candidates and dams were replaced by imputed genotypes from very low-density SNP genotypes (1000 SNPs), the increase in gain was 22% for the sire reference population and 42% for the sire and dam reference population. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…WAP-Cre × Lrp5 (FL/FL) dams had elevated serotonin concentrations in both the mammary gland and circulation compared to controls. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…From these abortion cases, bacteriological isolation was possible in only four dams while 16 dams were found to be serologically positive in Serum Tube Agglutination Test (STAT). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Using animal models of systemic maternal inflammation [intraperitoneal injection of lipopolysaccharide (LPS)] and fetal inflammation (intra-amniotic administration of LPS), we found that (1) systemic inflammation induced adverse pregnancy and neonatal outcomes by causing a severe maternal cytokine storm and a mild fetal cytokine response; (2) fetal inflammation induced adverse pregnancy and neonatal outcomes by causing a mild maternal cytokine response and a severe fetal cytokine storm; (3) exendin-4 (Ex4) treatment of dams with systemic inflammation or fetal inflammation improved adverse pregnancy outcomes by modestly reducing the rate of preterm birth; (4) Ex4 treatment of dams with systemic, but not local, inflammation considerably improved neonatal outcomes, and such neonates continued to thrive; (5) systemic inflammation facilitated the diffusion of Ex4 through the uterus and the maternal–fetal interface; (6) neonates born to Ex4-treated dams with systemic inflammation displayed a similar cytokine profile to healthy control neonates; and (7) treatment with Ex4 had immunomodulatory effects by inducing an M2 macrophage polarization and increasing anti-inflammatory neutrophils, as well as suppressing the expansion of CD8+ regulatory T cells, in neonates born to dams with systemic inflammation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The hypoxic dams had better glucose tolerance and insulin sensitivity compared with normoxic dams and failed to develop insulin resistance in late gestation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso