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1621por van Gisbergen, Klaas P.J.M., Sanchez-Hernandez, Marta, Geijtenbeek, Teunis B.H., van Kooyk, Yvette“…We demonstrate that neutrophils strongly cluster with immature DCs and that activated, not resting, neutrophils induce maturation of DCs that enables these DCs to trigger strong T cell proliferation and T helper type 1 polarization of T cells. This neutrophil–DC interaction is driven by the binding of the DC-specific, C-type lectin DC-SIGN to the β(2)-integrin Mac-1. …”
Publicado 2005
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1622por Hovius, Joppe W. R, de Jong, Marein A. W. P, den Dunnen, Jeroen, Litjens, Manja, Fikrig, Erol, van der Poll, Tom, Gringhuis, Sonja I, Geijtenbeek, Teunis B. H“…Salp15 interacts with DC-SIGN on DCs, which results in activation of the serine/threonine kinase Raf-1. …”
Publicado 2008
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1623por Müller, Martina, Fink, Kerstin, Geisel, Julia, Kahl, Frauke, Jilge, Burghardt, Reimann, Jörg, Mach, Nicolas, Autenrieth, Ingo B., Frick, Julia S.“…Mature but not semi-mature LP DC promoted Th1 polarization. As B. vulgatus mpk promotes differentiation of semi-mature DC presumably by IL-6, mRNA and protein expression of IL-6 was investigated in LP DC. …”
Publicado 2008
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1627“…We demonstrate that single-pass Kelvin force microscopy (KFM) and capacitance gradient (dC/dZ) measurements with force gradient detection of tip–sample electrostatic interactions can be performed in the intermittent contact regime in different environments. …”
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1628por Stax, Martijn J., Naarding, Marloes A., Tanck, Michael W. T., Lindquist, Susanne, Hernell, Olle, Lyle, Robert, Brandtzaeg, Per, Eggesbø, Merete, Pollakis, Georgios, Paxton, William A.“…Bile salt-stimulated lipase (BSSL) from human milk potently binds DC-SIGN and blocks DC-SIGN mediated trans-infection of CD4(+) T-lymphocytes with HIV-1. …”
Publicado 2011
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1629por Wuest, Simone C., Edwan, Jehad, Martin, Jayne F., Han, Sungpil, Perry, Justin S.A., Cartagena, Casandra M., Matsuura, Eiji, Maric, Dragan, Waldmann, Thomas A., Bielekova, Bibiana“…Our data reveal a novel mechanism for the IL-2 receptor system in DC-mediated activation of T cells.…”
Publicado 2011
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1630por Zeng, Weiqing, Brutus, Alexandre, Kremer, James M., Withers, John C., Gao, Xiaoli, Jones, A. Daniel, He, Sheng Yang“…COR-deficient mutants of P. s. tomato (Pst) DC3000 are severely compromised in virulence, especially when inoculated onto the plant surface. …”
Publicado 2011
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1631por Dirice, Ercument, Kahraman, Sevim, Elpek, Gulsum Ozlem, Aydin, Cigdem, Balci, Mustafa Kemal, Omer, Abdulkadir, Sanlioglu, Salih, Sanlioglu, Ahter Dilsad“…Specific increases observed in TRAIL ligand and DcR1 expressions may be part of a defensive strategy of the beta islets against the infiltrating leukocytes, while the immune-suppressive agent CY may partly hold down this defense, contributing further to diabetes development.…”
Publicado 2011
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1632por Filiatrault, Melanie J., Stodghill, Paul V., Myers, Christopher R., Bronstein, Philip A., Butcher, Bronwyn G., Lam, Hanh, Grills, George, Schweitzer, Peter, Wang, Wei, Schneider, David J., Cartinhour, Samuel W.“…Using a modified RNA-Seq approach and Illumina's high-throughput sequencing technology, we globally identified 5′-ends of transcripts for the plant pathogen Pseudomonas syringae pv. tomato str. DC3000. A substantial fraction of 5′-ends obtained by this method were consistent with results obtained using global RNA-Seq and 5′RACE. …”
Publicado 2011
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1634por Yu, Hong-Ren, Chang, Wei-Pin, Wang, Lin, Lin, Ying-Jui, Liang, Chi-Di, Yang, Kuender D., Kuo, Chiu-Ming, Huang, Yi-Chuan, Chang, Wei-Chiao, Kuo, Ho-Chang“…The G allele of DC-SIGN promoter −336 (rs4804803) is a risk allele in the development of KD.…”
Publicado 2012
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1636por Chinnery, Fay, King, Catherine A., Elliott, Tim, Bateman, Andrew R., James, Edward“…HN-expressing B16.OVA tumor cells induced stronger activation of NK cells compared with B16.OVA cells and also promoted dendritic cell (DC) activation toward a DC1 phenotype, in vitro. …”
Publicado 2012
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1637por Mesman, Annelies W., de Vries, Rory D., McQuaid, Stephen, Duprex, W. Paul, de Swart, Rik L., Geijtenbeek, Teunis B. H.“…In vitro studies have shown that dendritic cell (DC) C-type lectin DC-SIGN captures MV, leading to infection of DCs as well as transmission to lymphocytes. …”
Publicado 2012
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1638por Beisner, Daniel R., Langerak, Petra, Parker, Albert E., Dahlberg, Carol, Otero, Francella J., Sutton, Sue E., Poirot, Laurent, Barnes, Whitney, Young, Michael A., Niessen, Sherry, Wiltshire, Tim, Bodendorf, Ursula, Martoglio, Bruno, Cravatt, Benjamin, Cooke, Michael P.“…Proteomic analysis identified the invariant chain (CD74) as a key substrate of Sppl2a and suggests that regulated intramembrane proteolysis of CD74 by Sppl2a contributes to B cell and DC survival. Moreover, these data suggest that modulation of Sppl2a may be a useful therapeutic strategy for treatment of B cell dependent autoimmune disorders.…”
Publicado 2013
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1639por Cai, Minchao, Wu, Jing, Mao, Chaoming, Ren, Jianmin, Li, Pu, Li, Xiao, Zhong, Jiuchang, Xu, Chundi, Zhou, Tong“…BACKGROUND: Interactions between dendritic cells (DCs) and T cells play a critical role in the development of glomerulonephritis, which is a common cause of chronic kidney disease. DC-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN), an immune-regulating molecule of the C-type lectin family, is mainly expressed on DCs and mediates DC adhesion and migration, inflammation, activation of primary T cells. …”
Publicado 2013
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1640por Wu, Xiaodi, Satpathy, Ansuman T., KC, Wumesh, Liu, Pentao, Murphy, Theresa L., Murphy, Kenneth M.“…Recent bioinformatic analysis of global gene expression patterns has suggested a role for Bcl11a in the development of dendritic cell (DC) lineages. We tested this hypothesis by analyzing the development of DC and other lineages in Bcl11a (−/−) mice. …”
Publicado 2013
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