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  1. 2201
    “…However, there is controversy on the role of estrogen or progesterone on circulating NK (CD56(dim) and CD56(bright)) and NKT cells’ subsets. Here, we show a significantly increased activation of CD3(+)CD56(+)CD8(+) cells in pregnant MS women (MSP) compared with non-pregnant MS women (NPMS) (p < 0.001) and even with respect to healthy pregnant women (HP, p < 0.001), remaining increased even after delivery. …”
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    Activation of Blood CD3(+)CD56(+)CD8(+) T Cells during Pregnancy and Multiple Sclerosis
  2. 2202
    “…Patients with vitamin D deficiency, when compared to those with insufficient or normal vitamin D levels, had increased levels of IL-6 (23%; p<0.01), TNF-α (21%, p = 0.03), D-dimer (24%, p = 0.01), higher proportions of CD14(dim)CD16+ (22%, p<0.01) and CX3CR1+ monocytes (48%; p<0.001) and decreased frequency of CCR2+ monocytes (-3.4%, p<0.001). …”
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    Vitamin D deficiency is associated with IL-6 levels and monocyte activation in HIV-infected persons
  3. 2203
    “…RESULTS: Co-localization experiments performed with both anti-PTPRG antibodies identified the presence of isoforms and confirmed protein downregulation at diagnosis in the Philadelphia-positive myeloid lineage (including CD34(+)/CD38(bright/dim) cells). After effective tyrosine kinase inhibitor (TKI) treatment, its expression recovered in tandem with the return of Philadelphia-negative hematopoiesis. …”
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    A new monoclonal antibody detects downregulation of protein tyrosine phosphatase receptor type γ in chronic myeloid leukemia patients
  4. 2204
    “…Features consistent with immune compromise were also detected, notably elevated numbers of immune suppressive CD16(BRIGHT) CD62L(DIM) neutrophils (82.07 x 10(6)/l ± 18.94 control versus 1,092 x 10(6)/l ± 165 trauma, p < 0.0005) and CD14(+)HLA-DR(low/−) monocytes (34.96 x 10(6)/l ± 4.48 control versus 95.72 x 10(6)/l ± 8.0 trauma, p < 0.05) and reduced leukocyte cytokine secretion in response to lipopolysaccharide stimulation. …”
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    Prehospital immune responses and development of multiple organ dysfunction syndrome following traumatic injury: A prospective cohort study
  5. 2205
    “…Age-adjusted estimates of heritability were significant for all parameters (except scotopic dim-flash b-wave implicit time), ranging from 0.34 to 0.85. …”
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    Relative Genetic and Environmental Contributions to Variations in Human Retinal Electrical Responses Quantified in a Twin Study
  6. 2206
    “…METHODS: By rearing rd10/S1R(−/−) and rd10/S1R(+/+) mice in dim light to decelerate rapid rod/cone degeneration, we were able to compare their retinal biochemistry, histology and functions throughout postnatal 3–6 weeks (3 W–6 W). …”
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    Role of the sigma-1 receptor chaperone in rod and cone photoreceptor degenerations in a mouse model of retinitis pigmentosa
  7. 2207
    “…CD3(-)CD56(+) lymphoctes were gated using flow cytometry and further divided into CD56(dim) and CD56(bright) subsets according to the MFI of CD56. …”
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    Activating and inhibitory receptors on natural killer cells in patients with systemic lupus erythematosis-regulation with interleukin-15
  8. 2208
    “…In addition, IL-23 displayed a synergistic effect with IL-18 for IFN-γ production by both CD56(bright) and CD56(dim) NK cells, and this effect was due to a priming effect of IL-23 for IL-18 responsiveness. …”
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    Interleukin (IL)-23 Stimulates IFN-γ Secretion by CD56(bright) Natural Killer Cells and Enhances IL-18-Driven Dendritic Cells Activation
  9. 2209
    “…METHODS: Twenty healthy participants were fitted with ambulatory polysomnography (PSG) and wrist-actigraphs to assess light exposure, rest–activity, sleep quality, timing, and architecture. Laboratory salivary dim-light melatonin onset was analyzed to determine endogenous circadian phase. …”
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    Linking Light Exposure and Subsequent Sleep: A Field Polysomnography Study in Humans
  10. 2210
    “…However, the potent IFN-γ-producing subset, CD56(bright) NK cells, expressed higher levels of miR-146a than the lesser IFN-γ-producing subset, CD56(dim) NK cells. We also observed that co-stimulation of IL-12 and IL-18 significantly increased miR-146a expression in bulk NK cells and in the CD56(bright) subset in a time-dependent manner, correlating with augmented IFN-γ production. …”
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    Regulation of Human Natural Killer Cell IFN-γ Production by MicroRNA-146a via Targeting the NF-κB Signaling Pathway
  11. 2211
    “…In the absence of antigen stimulation, otitis-prone children had more circulating Natural Killer (NK) cells (p<0.01), particularly NK(dim) (CD56(lo)) cells (p<0.01), but fewer CD4(+) T cells (p<0.01) than healthy controls. …”
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    Evidence of functional cell-mediated immune responses to nontypeable Haemophilus influenzae in otitis-prone children
  12. 2212
    “…“Finding dropped objects” had the strongest correlation to CFI of better eye (r = −0.676) and “adjusting to dim lights” had the weakest correlation (r = −0.052). …”
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    Correlation of central field index (10–2 visual field analysis) and activity limitation with increasing severity of glaucoma using glaucoma activity limitation-9 questionnaire
  13. 2213
    “…Analysis of gene duplication and loss in visual and olfactory gene families supports a dim-light ancestral condition in snakes and indicates that olfactory receptor repertoires underwent an expansion early in snake evolution. …”
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    Molecular Adaptations for Sensing and Securing Prey and Insight into Amniote Genome Diversity from the Garter Snake Genome
  14. 2214
    “…Survivors are randomized to either an intervention (exposure to bright white light) or a comparison group (exposure to dim white light). The longitudinal design includes four measurement points at baseline (T0), post-intervention at 3.5 weeks (T1), 3 months post-intervention (T2) and 9 months post-intervention (T3). …”
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    Light therapy as a treatment of cancer-related fatigue in (non-)Hodgkin lymphoma survivors (SPARKLE trial): study protocol of a multicenter randomized controlled trial
  15. 2215
    “…However, the procedure is technically complicated and requires procedural skills, as SLN biopsy must be conducted in dim light conditions. As an improved version of this method, we introduced a combined method (Combined mixed dye and fluorescence; CMF) consisting of indigo carmine blue dye and FI. …”
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    Comparison of the indocyanine green dye method versus the combined method of indigo carmine blue dye with indocyanine green fluorescence imaging for sentinel lymph node biopsy in breast conservative therapy for stage ≤IIA breast cancer
  16. 2216
    “…Immunohistochemistry results revealed that FAM129B showed negative or dim expression in normal lung tissues while presented positive cytoplasmic expression in both squamous cell lung carcinoma and lung adenocarcinoma. …”
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    FAM129B promoted tumor invasion and proliferation via facilitating the phosphorylation of FAK signaling and associated with adverse clinical outcome of non-small cell lung cancer patients
  17. 2217
    “…After the intervention, depressive symptoms were significantly reduced [t((23)) = 6.9, p < 0.001] and, on average, the timing of dim light melatonin onset (DLMO) shifted 3.6 h earlier [t((18)) = 4.4, p < 0.001]. …”
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    Parallel Changes in Mood and Melatonin Rhythm Following an Adjunctive Multimodal Chronobiological Intervention With Agomelatine in People With Depression: A Proof of Concept Open Label Study
  18. 2218
    “…To investigate the effects and mechanisms of these TKIs on NK cells, here we characterized activating and inhibitory NK receptors in CD3(−)CD16(+)CD56(dim) NK cells isolated from CML patients in chronic phase (CP). …”
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    NKG2A Down-Regulation by Dasatinib Enhances Natural Killer Cytotoxicity and Accelerates Effective Treatment Responses in Patients With Chronic Myeloid Leukemia
  19. 2219
    “…A significant decrease in the percentage of a subset of regulatory NK cells (CD7(+)/CD3(−)/CD56(bright)/CD16(dim/−)) was identified in the peripheral blood of lymphoma patients compared to healthy blood donors (p = 0.003). …”
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    Altered profile of immune regulatory cells in the peripheral blood of lymphoma patients
  20. 2220
    “…Finally, we observed a significant alteration of crypt-villus morphology upon combination of DIM (EMT inhibitor) with CPT nullified the background EMT signals thus improving the efficacy of the DNA damaging agent. …”
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    Vimentin activation in early apoptotic cancer cells errands survival pathways during DNA damage inducer CPT treatment in colon carcinoma model
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