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  1. 361
    “…3,3’-Diindolylmethane (DIM) is found in cruciferous vegetables and is used to treat various inflammatory diseases because of its potential anti-inflammatory effects. …”
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    Anti-inflammatory activity of diindolylmethane alleviates Riemerella anatipestifer infection in ducks
  2. 362
    “…BACKGROUND: 3, 3′diindolylmethane (DIM), a natural phytochemical, has shown inhibitory effects on the growth and migration of a variety of cancer cells; however, whether DIM has similar effects on vascular smooth muscle cells (VSMCs) remains unknown. …”
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    3,3′Diindolylmethane Suppresses Vascular Smooth Muscle Cell Phenotypic Modulation and Inhibits Neointima Formation after Carotid Injury
  3. 363
    “…The proliferation inhibition and apoptosis induction by DIM were also blunted. In addition, DIM increased [Ca(2+)](i) in HCC cells, and this effect was inhibited by the calcium chelator, BAPTA-AM, resulting in reduced p-p38 MAPK activation and apoptosis in DIM-treated cells, though the proliferation inhibition by DIM was unchanged. …”
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    Anti-Cancer Effects of 3, 3’-Diindolylmethane on Human Hepatocellular Carcinoma Cells Is Enhanced by Calcium Ionophore: The Role of Cytosolic Ca(2+) and p38 MAPK
  4. 364
    “…The reduced theory is consistently truncated to $N=4$ 3D supergravity coupled to $4(1+\textrm{dim}\, G)$ bosonic and $4(1+\textrm{dim}\, G)$ fermionic propagating degrees of freedom. …”
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    3D gauged supergravity from SU(2) reduction of $N=1$ 6D supergravity
  5. 365
    “…Using Mtb mutants deleted for genes involved in DIM biosynthesis, we demonstrated that DIM participate both in the receptor-dependent phagocytosis of Mtb and the prevention of phagosomal acidification. …”
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    Phthiocerol Dimycocerosates of M. tuberculosis Participate in Macrophage Invasion by Inducing Changes in the Organization of Plasma Membrane Lipids
  6. 366
    por Seely, C.R., McArt, J.A.A.
    Publicado 2022
    “…The objectives of our study were to describe the association between SCH status at 4 d in milk (DIM) with the odds of pregnancy to first service and time to pregnancy through 150 DIM. …”
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    The association of subclinical hypocalcemia at 4 days in milk with reproductive outcomes in multiparous Holstein cows
  7. 367
    “…Dietary ligands resveratrol (RES) and 3,3′diindolylmethane (DIM) also activate ERα while only DIM activates AHR and RES represses it. …”
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    Resveratrol and 3,3′-Diindolylmethane Differentially Regulate Aryl Hydrocarbon Receptor and Estrogen Receptor Alpha Activity through Multiple Transcriptomic Targets in MCF-7 Human Breast Cancer Cells
  8. 368
    “…Certain bioactive food components, including indole-3-carbinol (I3C) and 3,3′-diindolylmethane (DIM) from cruciferous vegetables, have been shown to target cellular pathways regulating carcinogenesis. …”
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    3,3′-Diindolylmethane Induces G(1) Arrest and Apoptosis in Human Acute T-Cell Lymphoblastic Leukemia Cells
  9. 369
    “…Phytochemicals such as sulforaphane (SFN) and 3,3′-diindolylmethane (DIM) are promising chemopreventive agents for the treatment of prostate cancer. …”
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    Effects of Sulforaphane and 3,3′-Diindolylmethane on Genome-Wide Promoter Methylation in Normal Prostate Epithelial Cells and Prostate Cancer Cells
  10. 370
    “…OBJECTIVE: To assess the use of driving-impairing medicines (DIM) in the general population with special reference to length of use and concomitant use. …”
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    Use of driving-impairing medicines by a Spanish population: a population-based registry study
  11. 371
    “…This study aimed to incorporate nanocapsules containing 3,3′-diindolylmethane (DIM) with antitumor activity into a bilayer film of karaya and gellan gums for use in topical melanoma therapy. …”
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    Karaya/Gellan-Gum-Based Bilayer Films Containing 3,3′-Diindolylmethane-Loaded Nanocapsules: A Promising Alternative to Melanoma Topical Treatment
  12. 372
    “…PURPOSE: 3,3′-Diindolylmethane (DIM) is a natural component of cruciferous plants. …”
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    3,3′-Diindolylmethane Protects against Cardiac Hypertrophy via 5′-Adenosine Monophosphate-Activated Protein Kinase-α2
  13. 373
    “…DIM has been known for its anti-cancerous activity through various mechanisms. …”
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    Diindolylmethane Promotes Metabolic Crisis and Enhances the Efficacy of Centchroman in Breast Cancer: A (1)H NMR-Based Approach
  14. 374
    “…DIM enhanced the stemness of hucMSCs, which was related to the activation of Wnt/β-catenin signaling. β-catenin inhibition impaired the healing effects of DIM-primed hucMSCs (DIM-hucMSCs) in vivo. …”
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    3,3′-Diindolylmethane stimulates exosomal Wnt11 autocrine signaling in human umbilical cord mesenchymal stem cells to enhance wound healing
  15. 375
    “…Milk samples of each cow were collected at 3 DIM and 30 DIM for analyzing the milk compositions, including fatty acids (FA), amino acids and minerals. …”
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    A comparative study on milk composition of Jersey and Holstein dairy cows during the early lactation
  16. 376
    “…BACKGROUND: 3,3′-diindolylmethane (DIM) is an acid-catalyzed dimer of idole-3-carbinol (I3C), a phytochemical found in cruciferous vegetables that include broccoli, Brussels sprouts and cabbage. …”
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    Low levels of 3,3′-diindolylmethane activate estrogen receptor α and induce proliferation of breast cancer cells in the absence of estradiol
  17. 377
    “…In this study, the genotoxic effects of dimethoate (DIM) were investigated with the in vitro micronucleus test in human peripheral lymphocytes. …”
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    Herbal medicine against genotoxicity of dimethoate, an insecticide, in mammalian somatic cells
  18. 378
    “…3,3′-diindolylmethane (DIM), one of the active products derived from Brassica plants, is a promising antitumor agent. …”
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    3, 3′-Diindolylmethane Exhibits Antileukemic Activity In Vitro and In Vivo through a Akt-Dependent Process
  19. 379
    “…Surprisingly, nuclear transport of all known proteins involved in histone and DNA methylation, as well as a canonical transport substrate, appear normal in dim-3 strains. Interactions between DCDC members also appear normal, but the nup-6dim-3 allele causes the DCDC members DIM-5 and DIM-7 to mislocalize from heterochromatin and NUP-6(dim-3) itself is mislocalized from the nuclear envelope, at least in conidia. …”
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    Neurospora Importin α Is Required for Normal Heterochromatic Formation and DNA Methylation
  20. 380
    “…Polymerized whey protein (PWP)-based DIM nanoparticles were prepared at different mass ratios of protein and DIM by mixing PWP and DIM followed by ultrasound treatment for 4 min. …”
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    Physicochemical and Microstructural Properties of Polymerized Whey Protein Encapsulated 3,3′-Diindolylmethane Nanoparticles
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