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  1. 181
    “…The PARK7 gene encodes a protein, DJ-1, with several functions such as protection of cells from oxidative stress, sperm maturation and fertilization, and chaperone activity. …”
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    Dissembled DJ-1 high molecular weight complex in cortex mitochondria from Parkinson's disease patients
  2. 182
    “…Correction to Nural H, He P, Beach T, Sue L, Xia W, Shen Y. Disassembled DJ-1 high molecular weight complex in cortex mitochondria from Parkinson's disease patients Molecular Neurodegeneration 2009, 4:23.…”
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    Disassembled DJ-1 high molecular weight complex in cortex mitochondria from Parkinson's disease patients
  3. 183
    “…The mechanisms underlying the selective death of substantia nigra (SN) neurons in Parkinson disease (PD) remain elusive. While inactivation of DJ-1, an oxidative stress suppressor, causes PD, animal models lacking DJ-1 show no overt dopaminergic (DA) neuron degeneration in the SN. …”
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    Pro-Survival Role for Parkinson's Associated Gene DJ-1 Revealed in Trophically Impaired Dopaminergic Neurons
  4. 184
    por Shen, Z., Ren, Y., Ye, D., Guo, J., Kang, C., Ding, H.
    Publicado 2011
    “…The DJ-1 gene expression level was related to cell differentiation (P<0.05). …”
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    Significance and relationship between DJ-1 gene and survivin gene expression in laryngeal squamous cell carcinoma
  5. 185
    “…To explore DJ-1 protein's potential role in protecting against ischemic cell death, we constructed cell permeable Tat-DJ-1 fusion proteins. …”
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    Protective effects of transduced Tat-DJ-1 protein against oxidative stress and ischemic brain injury
  6. 186
    “…Loss-of-function mutations in DJ-1 (PARK7) gene account for about 1% of all familial Parkinson's disease (PD). …”
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    DJ-1 Interacts with and Regulates Paraoxonase-2, an Enzyme Critical for Neuronal Survival in Response to Oxidative Stress
  7. 187
    “…Regulation of DJ1 is associated with a number of human diseases. …”
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    Gender-dimorphic regulation of DJ1 and its interactions with metabolic proteins in streptozotocin-induced diabetic rats
  8. 188
    “…Lentiviral-delivered shRNA targeting DJ-1 could effectively knock down DJ-1 at mRNA and protein level (P<0.01). …”
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    DJ-1 Is Upregulated in Oral Squamous Cell Carcinoma and Promotes Oral Cancer Cell Proliferation and Invasion
  9. 189
    por Aslam, Kiran, Hazbun, Tony R.
    Publicado 2016
    “…Hsp31 is a homodimeric protein structurally similar to human DJ-1, a Parkinson's disease-linked protein, and both are members of the DJ-1/ThiJ/PfpI superfamily. …”
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    Hsp31, a member of the DJ-1 superfamily, is a multitasking stress responder with chaperone activity
  10. 190
    “…Increased lung nodule formation in DJ-1 KO mice following intravenous injection of melanoma cells was inhibited by GHR knockdown in B16F10 cells. …”
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    Growth hormone is increased in the lungs and enhances experimental lung metastasis of melanoma in DJ-1 KO mice
  11. 191
    “…Following exposure of HL-60 cells to 1.25 mg/l DADS for 8 h, the protein expression levels of DJ-1 were significantly decreased in the cytoplasm, while nuclear fractions exhibited a significant increase in DJ-1 expression when compared with untreated controls. …”
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    Subcellular localization of DJ-1 in human HL-60 leukemia cells in response to diallyl disulfide treatment
  12. 192
    “…DJ-1 has no direct effect on LPC proliferation. …”
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    DJ-1 deficiency attenuates expansion of liver progenitor cells through modulating the inflammatory and fibrogenic niches
  13. 193
    “…To help study this mechanism, we previously created resveratrol-enriched rice, DJ526, by transferring the resveratrol biosynthesis gene into Dongjin rice. …”
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    Gene expression profiles and physiological data from mice fed resveratrol-enriched rice DJ526
  14. 194
    “…DJ-1 (also known as PARK7) has been identified as a causal gene for hereditary recessive Parkinson’s disease (PD). …”
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    Parkinson’s disease-related DJ-1 functions in thiol quality control against aldehyde attack in vitro
  15. 195
    “…DJ-1, a Parkinson's disease-associated protein, is strongly up-regulated in reactive astrocytes in Parkinson's disease. …”
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    Astroglial DJ-1 over-expression up-regulates proteins involved in redox regulation and is neuroprotective in vivo
  16. 196
    “…In a previous study, we have shown that Tat-DJ-1 protein inhibits pancreatic RINm5F β-cell death caused by oxidative stress. …”
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    Protective effects of Tat-DJ-1 protein against streptozotocin-induced diabetes in a mice model
  17. 197
    “…Mitochondrial impairment is an important feature of Parkinson disease (PD), in which both familial parkinsonism genes DJ‐1 and PINK1 have a great impact on mitochondrial function. …”
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    Reduction of PINK1 or DJ‐1 impair mitochondrial motility in neurites and alter ER‐mitochondria contacts
  18. 198
    “…We have identified the whole-genome sequence of Lactobacillus salivarius DJ-sa-01, a potential probiotic strain for poultry, isolated from a chicken small intestine. …”
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    Whole-Genome Sequence of Lactobacillus salivarius DJ-sa-01, Isolated from Chicken Small Intestine
  19. 199
    “…However, no study exists regarding DJ-1 in plasma neural-derived exosomes. In the present study, the levels of DJ-1 and α-synuclein in plasma neural-derived exosomes were studied together in order to investigate novel biomarkers for PD. …”
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    Increased DJ-1 and α-Synuclein in Plasma Neural-Derived Exosomes as Potential Markers for Parkinson’s Disease
  20. 200
    “…The anti-cancer effects of CPX involved the downregulation of DJ-1, and overexpression of DJ-1 could reverse the cytotoxic effect of CPX on CRC cells. …”
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    CPX Targeting DJ-1 Triggers ROS-induced Cell Death and Protective Autophagy in Colorectal Cancer
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