Mostrando 121 - 140 Resultados de 4,462 Para Buscar '"DJ"', tiempo de consulta: 0.53s Limitar resultados
  1. 121
    “…Protein/nucleic acid deglycase DJ-1 (DJ-1) is a 20-kDa conserved protein, which belongs to the DJ-1/ThiJ/Pfp I protein superfamily. …”
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  2. 122
  3. 123
    “…Knockdown of DJ-1 decreased K-RAS expression, membrane translocation, and activity in BxPC-3 cells. …”
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  4. 124
    “…BACKGROUND & AIMS: DJ-1 is universally expressed in various tissues and organs and is involved in the physiological processes in various liver diseases. …”
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  5. 125
    “…The DJ-1 gene is highly conserved across a wide variety of organisms and it plays a role in anti-oxidative stress mechanisms in cells. …”
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  6. 126
    “…To achieve this goal, we used a Drosophila PD model based on inactivation of the DJ-1β gene (ortholog of human DJ-1). Metabolomic analyses were performed in 1-day-old and 15-day-old DJ-1β mutants and control flies using (1)H nuclear magnetic resonance spectroscopy, combined with expression and enzymatic activity assays of proteins implicated in altered pathways. …”
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  7. 127
  8. 128
  9. 129
    “…In this review, therefore, we discuss our current knowledge about PARK7/DJ-1 in the context of GBA diseases.…”
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  10. 130
    “…Our past studies have shown that DJ-1 is upregulated in HCC, while DJ-1 knockdown inhibits HCC xenograft-induced tumor growth and regeneration, implying that DJ-1 may be a potential target in for HCC treatment. …”
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  11. 131
    “…To explore the possible involvement of DJ-1 in such a pathway in vivo, we exposed Drosophila melanogaster to anoxia and evaluated the effect of DJ-1 on fly survival and SOD1 levels, in the presence or absence of CCS. …”
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  12. 132
    “…Previously, we provided the evidence for a central role of endogenous DJ-1 in the cardioprotection of post-conditioning. …”
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  13. 133
    por Bross, Irwin D. J.
    Publicado 1953
    Libro
  14. 134
    Publicado 1990
    Libro
  15. 135
    “…Parkinson’s disease (PD) is the second most common neurodegenerative disorder in human and loss-of-functions DJ-1 mutations are associated with a familial form of early onset PD. …”
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  16. 136
    “…Analysis of NOR sequences also identified LncRNA_038958 in the DJ, a candidate transcript with the region of the suggested promoter that is located close to the DJ/rDNA boundary and contains CTCF binding sites. …”
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  17. 137
    “…Yet, although protection against oxidative stress is the most prominent task ascribed to DJ-1, the underlying mechanisms linking DJ-1 deficiency to the onset of PD are a current matter of investigation. …”
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  18. 138
    por Sun, Mo E., Zheng, Qingfei
    Publicado 2023
    “…DJ-1 (also known as PARK7) is a multifunctional enzyme in human beings that is highly conserved and that has also been discovered in diverse species (ranging from prokaryotes to eukaryotes). …”
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  19. 139
  20. 140
    “…Here, we determined that the PD-associated protein DJ-1 plays an essential role in modulating DNA double-strand break (DSB) repair. …”
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