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Mostrando 321 - 340 Resultados de 431 Para Buscar '"Diablo"', tiempo de consulta: 0.15s Limitar resultados
  1. 321
    “…Antagonism strategies to modulate the actions of XIAP, cIAP1/2 and survivin are the central focus of current research and this review highlights advances within this field with particular emphasis upon the development and specificity of second mitochondria-derived activator of caspase (SMAC) mimetics (synthetic analogs of endogenously expressed inhibitors of IAPs SMAC/DIABLO). While we highlight the potential of SMAC mimetics as effective single agent or combinatory therapies to treat cancer we also discuss the likely clinical implications of resistance to SMAC mimetic therapy, occasionally observed in cancer cell lines.…”
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    Overcoming chemotherapy drug resistance by targeting inhibitors of apoptosis proteins (IAPs)
  2. 322
    “…Proapoptotic proteins such as Smac/DIABLO, EndoG, AIF (apoptosis-inducing factor), and cytochrome C are effective in apoptosis. …”
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    Immunology and Genetic of Leishmania infantum: The Role of Endonuclease G in the Apoptosis
  3. 323
    “…Finally, we investigated the biologically functional cellular target of S11e using a mass spectrometry approach, and identified that Diablo/SMAC protein is a cellular binding protein of S11e, by interacting to which S11e inhibited HT1080 cell migration and invasion. …”
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    DNA aptamer S11e recognizes fibrosarcoma and acts as a tumor suppressor
  4. 324
    “…Our results suggested that in NASH-related malignancy, α1-NKA signaling causes upregulation of the anti-apoptotic protein survivin and downregulation of the pro-apoptotic protein Smac/DIABLO via the activation of the PI3K → Akt pro-survival pathway with concomitant inhibition of the FoxO3 circuit, favoring cell division and primary liver carcinogenesis. …”
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    Tumor-Suppressor Role of the α1-Na/K-ATPase Signalosome in NASH Related Hepatocellular Carcinoma †
  5. 325
    Publicado 1998
    Tabla de Contenidos: “…. -- v.20. El Anfóra del diablo : novísimos cuentistas cubanos / selección y prólogo Salvador Redonet ; edición José Antonio Michelena…”
    Libro
    Cuadernos de cultura popular.
  6. 326
    Publicado 1993
    Tabla de Contenidos: “…Veal / Daniel Defoe -- Luvina / Juan Rulfo -- La posada del mal hospedaje / Lope de Vega -- La ciudad sin nombre / H.P: Lovecraft -- El joven Goodman Brown / Nathaniel Hawthorne -- La mano encantada / Gérard de Nerval -- Los constructores de puentes / Rudyard Kipling -- La nariz / Nikolai Gogol -- Una extraña entrevista / Charles Dickens -- La noche / Guy de Maupassant -- La mujer alta / Pedro Antonio de Alarcón -- Tres pesadillas / Ilán Stavans -- La casa del juez / Bram Stoker -- La larva / Rubén Darío -- El almohadón de plumas / Horacio Quiroga -- El desconocido / Ambrose Bierce -- Una salita cerca de la calle Edgware / Graham Greene -- En el bosque / Ryunosuke Akutagawa -- El diablo en la botella / Robert Louis Stevenson -- La cena / Alfonso Reyes -- La pata de mono / W. …”
    Libro
    Antología de cuentos de misterio y terror /
  7. 327
    Publicado 2006
    Tabla de Contenidos: “…Paz Gago -- Metadiégesis y pseudodiégesis en la narrativa de Juan Valera / Tilmann Altenberg -- El desafío perpetuo al lector "Tema del traidor y del heroe" : Jorge Luis Borges, Artíficios, 1944 / Dieter Janik -- Lo fantástico como transgresión : postulación fantástica en los relatos borgianos / Herminina Gil Guerrero -- La narración paradójica en Las babas del diablo y Apocalipsis de Solentiname de Julio Cortázar / Klaus Meyer-Minnemann -- Una carta imposible desde un paIs inexistente : copi contra las convenciones narrativas en El uruguayo / Patricio Pron -- Subversión de la doxa narrativa en La ciudad ausente de Ricardo Piglia / Elsa Dehennin.…”
    Libro
    La narración paradójica : "normas narrativas" y el principio de la "transgresión" /
  8. 328
    Publicado 2011
    Video DVD
    El rito = The rite /
  9. 329
    “…Moreover, expression of the IAP inhibitor DIABLO was increased at doses 10% and 15% of As. The germ cell death process induced by As might be related to a decrease in testosterone production because of the reduced expression of steroidogenic enzymes (Star, Cyp11a, Hsd3b5 and Hsd17b). …”
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    Chronic crude garlic-feeding modified adult male rat testicular markers: mechanisms of action
  10. 330
    “…And the mechanism of adaptor self-degradation and reciprocal control of the abundance between adaptor and its substrates is also applied to BTB-Cul3 E3 ligase adaptor dKeap1, dDiablo and dKLHL18.…”
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    Stability of HIB-Cul3 E3 ligase adaptor HIB Is Regulated by Self-degradation and Availability of Its Substrates
  11. 331
    “…The results indicated that F7 was able to induce apoptosis through MMP disruption, activation of caspases and increament of proapoptotic genes Bax and Smac/DIABLO. Moreover, our observation indicated that F7 is able to increase the cytotoxicity of DOX in SKNMC cells. …”
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    A semipolar fraction of petroleum ether extract of Artemisia aucheri induces apoptosis and enhances the apoptotic response to doxorubicin in human neuroblastoma SKNMC cell line
  12. 332
    “…Furthermore, by employing a panel of ccRCC-derived cell lines with silenced SRSF2 expression and qPCR arrays we show that SRSF2 contributes not only to splicing patterns but also to expression of multiple apoptotic genes, including new SRSF2 targets: DIABLO, BIRC5/survivin, TRAIL, BIM, MCL1, TNFRSF9, TNFRSF1B, CRADD, BCL2L2, BCL2A1, and TP53. …”
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    Decreased Expression of SRSF2 Splicing Factor Inhibits Apoptotic Pathways in Renal Cancer
  13. 333
    “…The presence of the mitochondrial protein SMAC/Diablo in the nucleus was found to be a signature for SCC. …”
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    A molecular signature of lung cancer: potential biomarkers for adenocarcinoma and squamous cell carcinoma
  14. 334
    “…GTN significantly altered apoptosis-related protein expressions, including Noxa, PUMA, Bax, Bim, Bad, Bcl-2, Bcl-xL, and DIABLO, which was related to the gene expression levels. …”
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    Apoptosis Induction via ATM Phosphorylation, Cell Cycle Arrest, and ER Stress by Goniothalamin and Chemodrugs Combined Effects on Breast Cancer-Derived MDA-MB-231 Cells
  15. 335
    “…Many small molecules have been designed to target the BIR domains, the vast majority being inspired by the N-terminal tetrapeptide of Second Mitochondria-derived Activator of Caspases/Direct IAp Binding with Low pI (Smac/Diablo), which is the natural XIAP antagonist. These compounds are therefore usually referred to as Smac mimetics (SMs). …”
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    Targeting the BIR Domains of Inhibitor of Apoptosis (IAP) Proteins in Cancer Treatment
  16. 336
    “…Con A-mediated cytosolic release of Smac/DIABLO and apoptosis-inducing factor (AIF), which are markers of necrosis, were dramatically decreased in HepG2 cells treated with SA. …”
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    Sicyos angulatus ameliorates acute liver injury by inhibiting oxidative stress via upregulation of anti-oxidant enzymes
  17. 337
    por Hoy, Marshal S., Ostberg, Carl O.
    Publicado 2019
    “…OBJECTIVE: A quantitative PCR (qPCR) assay for the detection of redside shiner (Richardsonius balteatus) environmental DNA (eDNA) was designed as a side product of a larger project aimed at using eDNA to determine the presence and geographic extent of native and non-native fishes in the reservoirs and associated tributaries above the three mainstem dams (Ross, Diablo, Gorge) on the Skagit River, Washington, USA. …”
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    Development of a quantitative PCR assay for detection of redside shiner (Richardsonius balteatus) from environmental DNA
  18. 338
    “…In addition, a decrease in apoptosis, determined by Caspase 3 activity and the expression of Cyt c and Smac/Diablo, were detected. Also, aspirin diminished necrosis process (LDH levels), pro-inflammatory mediators (IL-β and TNF-α) and NF-ᴋB protein expression, increasing anti-inflammatory PPAR-γ protein expression, preventing Aβ(1-42) toxic effects. …”
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    Action of low doses of Aspirin in Inflammation and Oxidative Stress induced by aβ(1-42) on Astrocytes in primary culture
  19. 339
    “…This FA signaling pathway in PC12 cells includes inactivation of pro-apoptotic proteins, SMAC/Diablo and Bad. In addition, FA attenuates the cell injury by H(2)O(2) through the inhibition of phosphorylation of the extracellular signal-regulated kinase (ERK). …”
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    Protective Effect of Ferulic Acid against Hydrogen Peroxide Induced Apoptosis in PC12 Cells
  20. 340
    “…SMAC/DIABLO and HTRA2 are mitochondrial proteins whose amino-terminal sequences, known as inhibitor of apoptosis binding motifs (IBMs), bind and activate ubiquitin ligases known as inhibitor of apoptosis proteins (IAPs), unleashing a cell’s apoptotic potential. …”
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    Overlap of NatA and IAP substrates implicates N-terminal acetylation in protein stabilization
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