“…The patient was labelled as a juvenile idiopathic arthritis patient and doomed to be a candidate for corticosteroid therapy. …”
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“…Furthermore, this result has also major impact on future conservation strategies as increasing the genetic diversity levels of declining species will be very difficult, and habitat quality should be high to maintain their populations, otherwise these species are doomed to disappear first.…”
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“…But its insoluble and unstable nature coupled with the high cost of synthesizing the endostatin protein doomed it for clinical cancer treatment. Intrigued by Folkman’s pioneering discoveries, Chinese scientists found a way to refold the protein, making it cost-effective to manufacture a recombinant human endostatin, a soluble and stable form of endostatin. …”
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“…A natural adaptation response is to engineer the coast in a perilous and often doomed attempt to preserve the status quo. In the long term, however, most coastal nations will need to transition to approaches based on ecological resilience—that is, to coastal zone management that allows coastal communities to absorb and adapt to change rather than to resist it—and the law will be critical in facilitating this transition. …”
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“…Third, I demonstrate why Assam is doomed to extinguish its revolutions before they happen. …”
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“…In a context of global change, this is particularly the case for plants which belong to high‐mountain ecosystems and, because of their ecological requirements, are doomed to survive or disappear on their “sky islands”. …”
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“…Spacetime, they say, is doomed. We heed the physicists, and drop the assumption that spacetime is fundamental. …”
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“…For the better part of a century, attempts to explain what was really going on in the quantum world seemed doomed to failure. But recent technological advances have made the question both practical and urgent. …”
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“…Prior knowledge of the quality of the vein can guide choice of therapeutic strategy, avoiding surgery that is doomed to failure. Discrepancies between intraoperative findings of the quality of the great saphenous vein and imaging tests are also frequently observed. …”
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“…CONCLUSION: We propose that adaptive advantages derived from worker reproduction for A. gracilipes may include 1) trophic eggs provisioned by physogastric workers likely assist colonies of A. gracilipes in overcoming unfavorable conditions such as paucity of food during critical founding stage; 2) worker-produced males are fertile and thus might offer an inclusive fitness advantage for the doomed orphaned colony. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12983-017-0210-4) contains supplementary material, which is available to authorized users.…”
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“…Unfortunately, the use of passwords is doomed because medical staff members share their passwords with one another. …”
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“…Incidental findings can influence the surgical plan, and in some instances, avoid doomed-to-fail and unsafe surgery. It is therefore important that these scans are reported by an experienced radiologist.…”
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“…The observation of serious inequalities in access to educational success for pupils from disadvantaged backgrounds could lead to a pessimistic vision suggesting that any possibility of transformation of the system is doomed to failure. Thus, the fight against inequalities in access to educational success is a form of runaway object which constitutes a challenge for research which treats the social context as evolving and susceptible to significant and novel transformations. …”
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“…Those analogies are often accompanied by dire warnings befalling those who “forget” or otherwise neglect the powerful lessons of History—and would then be “doomed to repeat it”, as the saying goes. So, Would remembering history make it seem more OR LESS likely to repeat itself in the future? …”
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“…Immune response of host body and immune suppression of tumor cells are modelled with four compartments in this study; viable tumor cells, T cell lymphocytes, immune triggering cells, and doomed cells. The growth of tumor was analyzed in two distinctive modes of tumor status (immune limited and immune escape) and its bifurcation condition. …”
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“…Immunosuppressive cancer therapies inadvertently re-invigorate pathogenic microorganisms and parasitic infections common to cancer, leading to a vicious circle of infection, autoimmunity and malignancy that ultimately dooms cancer patients. Based on this new understanding, we recommend a systemic approach to the development of cancer therapies that supports rather than antagonizes the immune system.…”
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“…Therefore, in theory, hypermutators are doomed to extinction unless they compensate the elevated mutational burden (deleterious load). …”
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“…In high-risk patients, doomed for reoperation the adverse effects of CBP may be more striking. …”
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