“…A total sample size of 300 was estimated to provide a power of 0.8 with a two-sided alpha of 0.05 for LDL-C, considering a 30% dropout rate. Pre-specified factors for subgroup analyses are HbA1c, use of DPP-4 inhibitors, sex, body mass index, LDL-C, age, and the presence of treatment for existing ischemic heart disease. …”
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“…Two publications reported a loss of efficacy or increased dropout rates. CONCLUSIONS: While use of each biologic must be assessed individually, these results provide reassurance to healthcare professionals and the public that the risk of immunogenicity-related safety concerns or diminished efficacy is unchanged after switching from a reference biologic to a biosimilar medicine. …”
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“…All participants included in the randomized study will be part of the analysis, and the final outcomes of any dropouts will be the value of their last visit (LOCF). …”
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“…Attendance for the IT sessions was 61.8% and the dropout rate was 32%. IT was associated with significant improvements on waist circumference (-2.72 cm, SE = 1.34; p = 0.04), negative symptoms (-2.93, SE = 1.34; p = 0.03), social (SOFAS) (+5.23, SE = 2.39; p = 0.03) and global functioning (+7.34, SE = 2.05; p < 0.001). …”
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“…All patients completed the SPEED questionnaire and underwent MG assessment, including lipid layer thickness (LLT), MG dropout (MGd), and MG expression. RESULTS: In total 31 eyes from 17 patients with unilateral or bilateral TED were included. …”
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“…Compliance rate was 69% and total dropout rate was 28%, both primarily related to disease progression and death. …”
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“…Important themes were premarital sex, forced marriage, lack of contraception, school dropout, fear of childbirth, financial insecurity, support structures and domestic violence. …”
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“…To achieve a power of 80% and allow for 10% dropout, 70 participants are needed in each arm. All analyses will be conducted on intention-to-treat bases and measured as differences between groups at 12 months follow-up. …”
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“…There were few intervention‐related adverse events, and dropout rate ranged from 12 to 20%. CONCLUSIONS: Findings suggest safety, effectiveness, and feasibility of adapted fitness training for screened nonambulatory stroke survivors. …”
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“…Background Patient compliance with the two-day Revised National Tuberculosis Control Programme’s (RNTCP) diagnostic process for pulmonary tuberculosis (TB) is poor in high case load settings, with a high dropout rate observed on the second day. Hence, the World Health Organization (WHO) has recommended the same-day (spot-spot) sputum test for high-burden TB countries to help reduce diagnostic dropouts. …”
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“…Although lower effectiveness and higher dropout rates of unguided than those of guided internet-based cognitive behavioral therapy remain critical issues, not incurring ongoing human clinical resources makes it highly advantageous. …”
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“…BACKGROUND: Automated Internet intervention studies have generally had large dropout rates for follow-up assessments. Live phone follow-ups have been often used to increase follow-up completion rates. …”
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“…DISCUSSION: Preselecting studies with regard to randomised controlled trials might induce bias due to dropout before the beginning of treatment or end of treatment. …”
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“…However, questions remain on the sustainability of this programme due to the high dropout cases of CHWs given their modest remuneration. …”
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“…Low QoL scores at baseline did not predict a higher risk of death or dropout. At 6-week interviews, as the side effect severity increased, patients were significantly less inclined to view the benefit of cancer control as worthwhile (X(2) = 50.7, P < 0.001). …”
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“…The median cost varied between 2.7 and 78 K€ for the test-and-cull protocols, vs. 120 K€ for WHD. The percentage of dropout ranged from 7.8 to 22%. The optimal tradeoff between epidemiological effectiveness, public costs, and acceptability to farmers was obtained for protocols with an increased delay (6 months instead of 2 in the currently used protocol) between the last two screening sessions, with either 3 or 2 screening sessions. …”
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“…METHODS: Patients from a single site (N=85) within a larger double-blind 12-week trial (N=245) showed a lower dropout rate (14% vs 40%) and used higher doses; therefore, this cohort was analyzed separately. …”
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“…RESULTS: The overall dropout rate at 3 years reached 19.3%. Treatment discontinuation rates were significantly different among treatment groups (aripiprazole=73.08%, ziprasidone=79.03%, and quetiapine=95.16%) (χ2=11.680; P=.001). …”
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“…However, the reasons for the high dropout during the screening-diagnostic process impacting the overall success of the screening program need to be identified and addressed.…”
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“…In contrast, greater caregiver disappointment at dropout was significantly associated with reported vaginal sex (OR 1.29, 95%CI: 1.14–1.46). …”
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