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21861por Li, Xin-Cang, Zhang, Xiao-Wen, Zhou, Jun-Fang, Ma, Hong-Yu, Liu, Zhi-Dong, Zhu, Lei, Yao, Xiao-Juan, Li, Lin-Gui, Fang, Wen-Hong“…Tube and Pelle are essential components in Drosophila Toll signaling pathway. In this study, we characterized a pair of crustacean homologs of Tube and Pelle in Scylla paramamosain, namely, SpTube and SpPelle, and analyzed their immune functions. …”
Publicado 2013
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21862“…To find functions for H3K27me3, we deleted the gene for the putative H3K27 methyltransferase, KMT6, a homolog of Drosophila Enhancer of zeste, E(z). The kmt6 mutant lacks H3K27me3, as shown by western blot and ChIP-seq, displays growth defects, is sterile, and constitutively expresses genes for mycotoxins, pigments and other secondary metabolites. …”
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21863por Zhao, Xiaoming, Su, Jiaming, Wang, Fei, Liu, Da, Ding, Jian, Yang, Yang, Conaway, Joan W., Conaway, Ronald C., Cao, Lingling, Wu, Donglu, Wu, Min, Cai, Yong, Jin, Jingji“…The male specific lethal (MSL) HAT complex plays a key role in dosage compensation in Drosophila and is responsible for histone H4K16ac in vivo. …”
Publicado 2013
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21864“…BACKGROUND: In Drosophila and many other insects, the Hox genes Ultrabithorax (Ubx) and abdominal-A (abd-A) suppress limb formation on most or all segments of the abdomen. …”
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21865por Toth, Amy L, Tooker, John F, Radhakrishnan, Srihari, Minard, Robert, Henshaw, Michael T, Grozinger, Christina M“…To explore whether conserved molecular pathways relate to dominance, we compared wasp transcriptomic data to previous studies of gene expression associated with pheromonal communication and queen-worker differences in honey bees, and aggressive behavior in bees, Drosophila, and mice. RESULTS: By examining dominant and subordinate females from queen and worker castes in early and late season colonies, we found that cuticular hydrocarbon profiles and genome-wide patterns of brain gene expression were primarily associated with season/social environment rather than dominance status. …”
Publicado 2014
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21866“…The Sec-dependent substrate utilization behavior of TR1 may be the exception and not the rule as we show that a variety of high-M(r) TRs from other organisms, including Drosophila melanogaster, Caenorhabditis elegans, and Plasmodium falciparum, do not require Sec to reduce small molecule substrates, including 5,5′-dithiobis(2-nitrobenzoic acid), lipoic acid, selenite, and selenocystine. …”
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21867por Koonin, Eugene V, Fedorova, Natalie D, Jackson, John D, Jacobs, Aviva R, Krylov, Dmitri M, Makarova, Kira S, Mazumder, Raja, Mekhedov, Sergei L, Nikolskaya, Anastasia N, Rao, B Sridhar, Rogozin, Igor B, Smirnov, Sergei, Sorokin, Alexander V, Sverdlov, Alexander V, Vasudevan, Sona, Wolf, Yuri I, Yin, Jodie J, Natale, Darren A“…RESULTS: We examined functional and evolutionary patterns in the recently constructed set of 5,873 clusters of predicted orthologs (eukaryotic orthologous groups or KOGs) from seven eukaryotic genomes: Caenorhabditis elegans, Drosophila melanogaster, Homo sapiens, Arabidopsis thaliana, Saccharomyces cerevisiae, Schizosaccharomyces pombe and Encephalitozoon cuniculi. …”
Publicado 2004
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21868por Edi, Constant V., Djogbénou, Luc, Jenkins, Adam M., Regna, Kimberly, Muskavitch, Marc A. T., Poupardin, Rodolphe, Jones, Christopher M., Essandoh, John, Kétoh, Guillaume K., Paine, Mark J. I., Koudou, Benjamin G., Donnelly, Martin J., Ranson, Hilary, Weetman, David“…CYP6P3 and especially CYP6M2 produced bendiocarb resistance via transgenic expression in Drosophila in addition to pyrethroid resistance for both genes, and DDT resistance for CYP6M2 expression. …”
Publicado 2014
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21869“…RESULTS: We employed Apvas1, a Drosophila vasa ortholog in the pea aphid, as a germline marker to examine whether germ plasm is preformed during oviparous development, as has already been seen in the viviparous embryos. …”
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21870“…Numerous nuclear genes were recently reported in Drosophila melanogaster, which exhibit male-specific patterns of differential expression when placed alongside different mtDNA haplotypes, suggesting that nuclear genes are sensitive to an underlying male-specific mitochondrial mutation load. …”
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21871“…Much is known about the initiation and regulation of Hox gene expression in Drosophila and vertebrates, but less is known in the non-arthropod invertebrate model system, C. elegans. …”
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21872por Zamani, Neda, Sundström, Görel, Meadows, Jennifer RS, Höppner, Marc P, Dainat, Jacques, Lantz, Henrik, Haas, Brian J, Grabherr, Manfred G“…We first evaluated the method on the set of 12 Drosophila genomes, finding that orthologous correspondence computed indirectly through a graph of multiple synteny maps comes at minimal cost in terms of sensitivity, but reduces overall computational runtime by an order of magnitude. …”
Publicado 2014
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21873por Sherman, Stephanie L, Curnow, Eliza C, Easley, Charles A, Jin, Peng, Hukema, Renate K, Tejada, Maria Isabel, Willemsen, Rob, Usdin, Karen“…Vertebrate (mouse and rat) and invertebrate (Drosophila melanogaster) animal studies for the FMR1 premutation and ovarian function exist and have been instrumental in advancing our understanding of the disease phenotype. …”
Publicado 2014
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21874por Andersson, Martin N, Videvall, Elin, Walden, Kimberly KO, Harris, Marion O, Robertson, Hugh M, Löfstedt, Christer“…The order Diptera contains two model organisms, the vinegar fly Drosophila melanogaster and the mosquito Anopheles gambiae, whose chemosensory genes have been extensively studied. …”
Publicado 2014
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21875por Leander, Megan, Bass, Chloe, Marchetti, Kathryn, Maynard, Benjamin F., Wulff, Juan Pedro, Ons, Sheila, Nichols, Ruthann“…Myosuppressin binds to G protein-coupled receptor (GPCR) proteins. Two Drosophila melanogaster myosuppressin receptors (DrmMS-Rs) exist; however, no mechanism underlying MS-R activation is reported. …”
Publicado 2015
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21876“…Although studies on different animals have revealed commonalities in gut formation, the model systems Caenorhabditis elegans and Drosophila melanogaster, which belong to the invertebrate group Ecdysozoa, exhibit remarkable deviations in how their intestines develop. …”
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21877por Chu, Chen, Fang, Zhaoben, Hua, Xing, Yang, Yaning, Chen, Enguo, Cowley, Allen W., Liang, Mingyu, Liu, Pengyuan, Lu, Yan“…We systematically evaluated our new tool in simulated datasets from several large-scale TCGA RNA-Seq projects, unbiased benchmark data from compcodeR package, and real RNA-Seq data from the development transcriptome of Drosophila. deGPS can precisely control type I error and false discovery rate for the detection of differential expression and is robust in the presence of abnormal high sequence read counts in RNA-Seq experiments. …”
Publicado 2015
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21878por Kinghorn, Kerri J., Castillo-Quan, Jorge Iván, Bartolome, Fernando, Angelova, Plamena R., Li, Li, Pope, Simon, Cochemé, Helena M., Khan, Shabana, Asghari, Shabnam, Bhatia, Kailash P., Hardy, John, Abramov, Andrey Y., Partridge, Linda“…Here we show that knockout of the Drosophila homologue of the PLA2G6 gene, iPLA2-VIA, results in reduced survival, locomotor deficits and organismal hypersensitivity to oxidative stress. …”
Publicado 2015
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21879por Sell-Kubiak, E., Duijvesteijn, N., Lopes, M. S., Janss, L. L. G., Knol, E. F., Bijma, P., Mulder, H. A.“…The first gene is coding a swine heat shock protein 90 (HSPCB = Hsp90), which is a well-studied gene stabilizing morphological traits in Drosophila and Arabidopsis. The second gene is VEGFA, which is activated in angiogenesis and vasculogenesis in the fetus. …”
Publicado 2015
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21880por Durst, Ronen, Sauls, Kimberly, Peal, David S, deVlaming, Annemarieke, Toomer, Katelynn, Leyne, Maire, Salani, Monica, Talkowski, Michael E., Brand, Harrison, Perrocheau, Maëlle, Simpson, Charles, Jett, Christopher, Stone, Matthew R., Charles, Florie, Chiang, Colby, Lynch, Stacey N., Bouatia-Naji, Nabila, Delling, Francesca N., Freed, Lisa A., Tribouilloy, Christophe, Le Tourneau, Thierry, LeMarec, Hervé, Fernandez-Friera, Leticia, Solis, Jorge, Trujillano, Daniel, Ossowski, Stephan, Estivill, Xavier, Dina, Christian, Bruneval, Patrick, Chester, Adrian, Schott, Jean-Jacques, Irvine, Kenneth D., Mao, Yaopan, Wessels, Andy, Motiwala, Tahirali, Puceat, Michel, Tsukasaki, Yoshikazu, Menick, Donald R., Kasiganesan, Harinath, Nie, Xingju, Broome, Ann-Marie, Williams, Katherine, Johnson, Amanda, Markwald, Roger R., Jeunemaitre, Xavier, Hagege, Albert, Levine, Robert A., Milan, David J., Norris, Russell A., Slaugenhaupt, Susan A.“…We report a missense mutation in the DCHS1 gene, the human homologue of the Drosophila cell polarity gene dachsous (ds) that segregates with MVP in the family. …”
Publicado 2015
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