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  1. 22101
    por Attardo, Geoffrey M., Abd-Alla, Adly M. M., Acosta-Serrano, Alvaro, Allen, James E., Bateta, Rosemary, Benoit, Joshua B., Bourtzis, Kostas, Caers, Jelle, Caljon, Guy, Christensen, Mikkel B., Farrow, David W., Friedrich, Markus, Hua-Van, Aurélie, Jennings, Emily C., Larkin, Denis M., Lawson, Daniel, Lehane, Michael J., Lenis, Vasileios P., Lowy-Gallego, Ernesto, Macharia, Rosaline W., Malacrida, Anna R., Marco, Heather G., Masiga, Daniel, Maslen, Gareth L., Matetovici, Irina, Meisel, Richard P., Meki, Irene, Michalkova, Veronika, Miller, Wolfgang J., Minx, Patrick, Mireji, Paul O., Ometto, Lino, Parker, Andrew G., Rio, Rita, Rose, Clair, Rosendale, Andrew J., Rota-Stabelli, Omar, Savini, Grazia, Schoofs, Liliane, Scolari, Francesca, Swain, Martin T., Takáč, Peter, Tomlinson, Chad, Tsiamis, George, Van Den Abbeele, Jan, Vigneron, Aurelien, Wang, Jingwen, Warren, Wesley C., Waterhouse, Robert M., Weirauch, Matthew T., Weiss, Brian L., Wilson, Richard K., Zhao, Xin, Aksoy, Serap
    Publicado 2019
    “…Syntenic analysis of Glossina relative to Drosophila melanogaster shows reduced structural conservation across the sex-linked X chromosome. …”
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    Comparative genomic analysis of six Glossina genomes, vectors of African trypanosomes
  2. 22102
    “…We show here that knock down (KD) of proteasome subunits in Drosophila flies, induced, for most subunits, developmental lethality. …”
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    Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy
  3. 22103
    “…Paired-like homeodomain 2 (Pitx2c) increase, microRNA-15b (miR-15b) low expression, and p53 phosphorylation (p-p53) upregulation, as well as activation of transforming growth factor-β1 (TGF-β1)/drosophila mothers against DPP homolog (Smads) signaling and connective tissue growth factor (CTGF) induction, were also detected in fructose-fed rat hearts and fructose-exposed rat myocardial cell line H9c2 cells. …”
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    Pterostilbene Attenuates Fructose-Induced Myocardial Fibrosis by Inhibiting ROS-Driven Pitx2c/miR-15b Pathway
  4. 22104
    “…Schnurri-3 (Shn3) is a large zinc finger protein related to Drosophila Shn, which is a critical mediator of postnatal bone formation. …”
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    RETRACTED ARTICLE: Schnurri-3 regulates BMP9-induced osteogenic differentiation and angiogenesis of human amniotic mesenchymal stem cells through Runx2 and VEGF
  5. 22105
    “…The samples represented virus-producing cell cultures (such as SARS-coronavirus, West Nile virus, Orthopox virus), bacteria suspensions (cultures of Escherichia coli and genetically knockout apathogenic Bacillus anthracis), suspensions of parasites (malaria Plasmodium falciparum, Leishmania major, Microsporidia cuniculi, Caenorhabditis elegans), and whole Drosophila melanogaster flies infected with microsporidia. …”
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    Microwave-assisted tissue processing for same-day EM-diagnosis of potential bioterrorism and clinical samples
  6. 22106
    “…FXS represents the leading heritable cause of ID and ASD, but many other genes that play roles in ID and ASD have yet to be identified. RESULTS: In a Drosophila FXS disease model, one dfmr1(50M) null mutant stock exhibits previously unreported axonal overgrowths at developmental and mature stages in the giant fiber (GF) escape circuit. …”
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    Genetic background mutations drive neural circuit hyperconnectivity in a fragile X syndrome model
  7. 22107
    “…Physical interaction between MASC and AS1 lncRNA may be important for the BmdsxM expression in the testis. Unlike in the Drosophila dsx, BmdsxM was able to induce spermatogenesis in genetically female (ZW) germ cells. …”
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    Transgenic and knockout analyses of Masculinizer and doublesex illuminated the unique functions of doublesex in germ cell sexual development of the silkworm, Bombyx mori
  8. 22108
    por Wang, Huajun, Zheng, Guangying
    Publicado 2020
    “…METHODS: The expression of NEAT1, microRNA-486-5p (miR-486-5p) and Drosophila mothers against decapentaplegic 4 (SMAD4) was determined using quantitative real-time polymerase chain reaction (qRT-PCR). …”
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    LncRNA NEAT1 promotes proliferation, migration, invasion and epithelial-mesenchymal transition process in TGF-β2-stimulated lens epithelial cells through regulating the miR-486-5p/SMAD4 axis
  9. 22109
    “…However, homologs of putative RNAi spreading defective-3 (Rsd-3) protein and scavenger receptors namely Eater and SR-CI that mediate endocytosis cellular update of dsRNA in C. elegans and Drosophila melanogaster were found in Acari genomes. …”
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    A genome-wide screening for RNAi pathway proteins in Acari
  10. 22110
    “…Protein sequence, the presence and number of conserved CAP-domains and phylogeny were used to group identified SCP/TAPS proteins; these were compared to those found in Drosophila melanogaster to make functional predictions. …”
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    Major SCP/TAPS protein expansion in Lucilia cuprina is associated with novel tandem array organisation and domain architecture
  11. 22111
    por Ye, Shaopan, Li, Jiaqi, Zhang, Zhe
    Publicado 2020
    “…In this study, simultaneously using whole-genome sequencing (WGS) and gene expression level data, four strategies for single-nucleotide polymorphism (SNP) preselection were investigated for genomic predictions in the Drosophila Genetic Reference Panel. RESULTS: Using genomic best linear unbiased prediction (GBLUP) with complete WGS data, the prediction accuracies were 0.208 ± 0.020 (0.181 ± 0.022) for the startle response and 0.272 ± 0.017 (0.307 ± 0.015) for starvation resistance in the female (male) lines. …”
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    Multi-omics-data-assisted genomic feature markers preselection improves the accuracy of genomic prediction
  12. 22112
    “…Toxicity studies on Drosophila validated normal egg laying capacity and eclosion of F1 generation on AI-AgNPs (100 μg/mL). …”
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    Synthesis, Characterization, Antibacterial and Wound Healing Efficacy of Silver Nanoparticles From Azadirachta indica
  13. 22113
    “…The close relationship of Stomoxys to other blood-feeding (horn flies and Glossina) and non-blood-feeding flies (house flies, medflies, Drosophila) will facilitate understanding of the evolutionary processes associated with development of blood feeding among the Cyclorrhapha. …”
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    The genome of the stable fly, Stomoxys calcitrans, reveals potential mechanisms underlying reproduction, host interactions, and novel targets for pest control
  14. 22114
    “…Research on plant pests has focused on the development of genetic sexing strains, characterizing and assessing the performance of these strains (e.g., Ceratitis capitata), elucidation of the taxonomic status of several members of the Bactrocera dorsalis and Anastrepha fraterculus complexes, the use of microbiota as probiotics, genomics, supplements to improve the performance of the reared insects, and the development of the SIT package for fruit fly species such as Bactrocera oleae and Drosophila suzukii. Research on livestock pests has focused on colony maintenance and establishment, tsetse symbionts and pathogens, sex separation, morphology, sterile male quality, radiation biology, mating behavior and transportation and release systems. …”
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    The Insect Pest Control Laboratory of the Joint FAO/IAEA Programme: Ten Years (2010–2020) of Research and Development, Achievements and Challenges in Support of the Sterile Insect Technique
  15. 22115
    “…The Model Organism Screening Center (MOSC) of the UDN is a unique resource dedicated to utilizing informatics and functional studies in model organisms, including worm (Caenorhabditis elegans), fly (Drosophila melanogaster), and zebrafish (Danio rerio), to aid in diagnosis. …”
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    Model organisms contribute to diagnosis and discovery in the undiagnosed diseases network: current state and a future vision
  16. 22116
    “…BACKGROUND: Most insects are relatively short-lived, with a maximum lifespan of a few weeks, like the aging model organism, the fruit-fly Drosophila melanogaster. By contrast, the queens of many social insects (termites, ants and some bees) can live from a few years to decades. …”
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    Disentangling the aging gene expression network of termite queens
  17. 22117
    “…We knocked hαSyn(TP) or hαSyn(Δ119) (h stands for “human”) into the murine αSyn locus. hαSyn(TP) is a structure-based mutant with triple alanine to proline substitutions that favors oligomers, is neurotoxic and evokes PD-like symptoms in Drosophila melanogaster. hαSyn(Δ119) lacks 21 amino acids at the C-terminus, favors fibrillary aggregates and occurs in PD. …”
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    Low-Expressing Synucleinopathy Mouse Models Based on Oligomer-Forming Mutations and C-Terminal Truncation of α-Synuclein
  18. 22118
    por Cao, Dong
    Publicado 2021
    “…Especially, circRNAs are enriched in the brain tissues of almost all investigated species, including humans, mice, Drosophila, etc. Although circRNAs were found in C. elegans, the neuron-specific circRNA data is not available yet. …”
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    Reverse complementary matches simultaneously promote both back-splicing and exon-skipping
  19. 22119
    “…Here, we isolate the mechanistic role of α-syn in mitochondrial homeostasis in vivo in a humanized Drosophila model of Parkinson’s disease (PD). We show that excess α-syn causes fragmented mitochondria, which persists with either truncation of the C-terminus (α-syn(1–120)) or deletion of the NAC region (α-syn(ΔNAC)). …”
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    Differential mitochondrial roles for α-synuclein in DRP1-dependent fission and PINK1/Parkin-mediated oxidation
  20. 22120
    “…R2D2 has been identified as a double-stranded RNA (dsRNA)-binding protein and reported as an integral component of the siRNA pathway in Drosophila. However, the involvement of R2D2 in the siRNA pathway of Locusta migratoria is still unknown. …”
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    Molecular Characterizations and Functional Analyses of LmR2D2 in the Locusta migratoria siRNA Pathway
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