“…Here we screen conserved 3′ UTR sequences from the Drosophila melanogaster genome for potential miRNA targets. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso

“…There are a number of ways to suppress electrical activity in Drosophila neurons, for instance, over-expression of potassium channels (i.e. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…To answer these questions we used Drosophila melanogaster, because its chemosensory systems are well characterized and both the genotype and environment can be controlled precisely. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, we investigate the regulatory ‘grammar’ of nearly 100 characterized enhancers for developmental control genes active in the early Drosophila embryo. The conservation of grammar is examined in seven divergent Drosophila genomes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this study, we demonstrate that autophagy positively regulates development of the Drosophila melanogaster larval neuromuscular junction (NMJ). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso

“…We determined copy number and transcript abundance (expression) genome-wide in Drosophila S2 cells by DNA-Seq and RNA-Seq. We found that S2 cells are aneuploid for >43 Mb of the genome, primarily in the range of one to five copies, and show a male genotype (∼ two X chromosomes and four sets of autosomes, or 2X;4A). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, by combining data on sex-specific fitness and genome-wide transcript abundance in a quantitative genetic framework, we identified a group of candidate genes experiencing sexually antagonistic selection in the adult, which correspond to 8% of Drosophila melanogaster genes. As predicted, the X chromosome is enriched for these genes, but surprisingly they represent only a small proportion of the total number of sex-biased transcripts, indicating that the latter is a poor predictor of sexual antagonism. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The detection of water and the regulation of water intake are essential for animals to maintain proper osmotic homeostasis1. Drosophila and other insects have gustatory sensory neurons that mediate the recognition of external water sources2-4, but little is known about the underlying molecular mechanism for water taste detection. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Previous studies have described Drosophila neurexin mutant phenotypes in third instar larvae and adults. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso
Enlace del recurso

“…During the last two decades, research using the genetically amenable fruitfly has established Drosophila melanogaster as a valuable model system in the study of human neurodegeneration. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Our results show extensive rearrangement of the Drosophila tRNA gene complement over the last 60 My. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…However, an age-related analysis of these baseline parameters in wildtype Drosophila is lacking. Here we analyzed the DA system and motor behavior in aging Drosophila. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Instead, the neutral ceramidase gene CDase encodes the protein that is responsible for all measurable ceramidase activity in Drosophila. Our studies show strong genetic interaction of Bwa with CDase and the Drosophila ceramide kinase gene (DCERK). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here we report a microarray analysis of gene expression variation among females of 16 Drosophila melanogaster strains derived from natural populations, including eight strains from the putative ancestral range in sub-Saharan Africa and eight strains from Europe. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In combination with classical and cell-type specific genetic approaches in Drosophila, this model is expected to provide new insights into the molecular and cellular mechanisms of tripartite synapse function.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Artificial selection is a powerful technique for uncovering selectable genetic variation; we review and critique the limited number of previous studies that have been performed to select on DA and present the results of a novel artificial selection experiment on the DA of posterior crossvein location in Drosophila wings. Fifteen generations of selection in two genetically distinct lines were performed and none of the lines showed a significant response to selection. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso