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202“…In this regard, Tetraphenylporphinesulfonate (TPPS), 5,10,15,20- Tetrakis (4-sulfonatophenyl) porphyrinato Iron(III) Chloride (FeTPPS) and 5,10,15,20-Tetrakis (4-sulfonatophenyl) porphyrinatoIron(III) nitrosyl Chloride (FeNOTPPS) were investigated as candidate compounds for inhibition of Acteylcholinesterase of Drosophila melanogaster (DmAChE) by use of Molecular Docking. …”
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203“…Attempting to differentiate causes from responses, we made a c-DNA microarray analysis of inbreeding depression in Drosophila melanogaster. The rationale of the experiment was that, while depression is a general phenomenon involving reductions in fitness in different inbred lines, its first genetic causes would be different for each inbred line, as they are expected to be caused by the fixation of rare deleterious genes. …”
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205
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206“…We report that establishment and maintenance of the Drosophila melanogaster microbiome depend on ingestion of bacteria. …”
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207“…The laboratory fruit fly, Drosophila melanogaster, is used widely in biological research, but the requirement to maintain stocks with a roughly biweekly generation time imposes substantial burdens of labor, potential cross-contamination and mutation accumulation. …”
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208por Marco, Antonio“…Here, I study the sex-biased expression pattern of microRNAs in the model species Drosophila melanogaster. As with protein-coding genes, sex-biased microRNAs are associated with the reproductive function. …”
Publicado 2014
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209“…The simplicity of the Notch pathway in Drosophila melanogaster, in combination with the availability of powerful genetics, make this an attractive model for studying fundamental principles of Notch regulation and function. …”
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210“…We examined if activating contact chemoreceptive sensilla could trigger grooming activities in Drosophila melanogaster. We monitored the grooming responses of decapitated flies to compounds known to activate the immune system, e.g., dead Escherichia coli (Ec) and lipopolysaccharides (LPS), and to tastants such as quinine, sucrose, and salt. …”
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211
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212por Ren, Xingjie, Yang, Zhihao, Mao, Decai, Chang, Zai, Qiao, Huan-Huan, Wang, Xia, Sun, Jin, Hu, Qun, Cui, Yan, Liu, Lu-Ping, Ji, Jun-Yuan, Xu, Jiang, Ni, Jian-Quan“…Recent studies of the Cas9/sgRNA system in Drosophila melanogaster genome editing have opened new opportunities to generate site-specific mutant collections in a high-throughput manner. …”
Publicado 2014
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213“…BACKGROUND: Phenotypic plasticity allows organisms to respond rapidly to changing environmental circumstances, and understanding its genomic basis can yield insights regarding the underlying genes and genetic networks affecting complex phenotypes. Female Drosophila melanogaster undergo dramatic physiological changes mediated by seminal fluid components transferred upon mating, including decreased longevity. …”
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214“…Drosophila melanogaster provides an important resource for in vivo modifier screens of neurodegenerative diseases. …”
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215“…In this study, we investigate the effect of biologically realistic levels of inbreeding on sex ratio and sex specific mortality in Drosophila melanogaster. We use two pedigree crossing designs to either maximise or minimise inbreeding on the X-chromosome whilst producing identical autosomal inbreeding. …”
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216por Moschetti, Roberta, Celauro, Emanuele, Cruciani, Fulvio, Caizzi, Ruggiero, Dimitri, Patrizio“…Here, we report the results of the evolutionary analysis of Yeti, an essential gene of Drosophila melanogaster located in the deep pericentromeric region of chromosome 2R. …”
Publicado 2014
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217por Misra, Snigdha, Kumar, Ajay, Ratnasekhar, Ch., Sharma, Vandana, Mudiam, Mohana Krishna Reddy, Ram, Kristipati Ravi“…Therefore, we exposed Drosophila melanogaster males to endosulfan, and evaluated their progeny production as well as the ability of their sperm to counter rival control sperm in the storage organs of females sequentially mated to control/exposed males. …”
Publicado 2014
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218por Hoskins, Roger A., Carlson, Joseph W., Wan, Kenneth H., Park, Soo, Mendez, Ivonne, Galle, Samuel E., Booth, Benjamin W., Pfeiffer, Barret D., George, Reed A., Svirskas, Robert, Krzywinski, Martin, Schein, Jacqueline, Accardo, Maria Carmela, Damia, Elisabetta, Messina, Giovanni, Méndez-Lago, María, de Pablos, Beatriz, Demakova, Olga V., Andreyeva, Evgeniya N., Boldyreva, Lidiya V., Marra, Marco, Carvalho, A. Bernardo, Dimitri, Patrizio, Villasante, Alfredo, Zhimulev, Igor F., Rubin, Gerald M., Karpen, Gary H., Celniker, Susan E.“…Drosophila melanogaster plays an important role in molecular, genetic, and genomic studies of heredity, development, metabolism, behavior, and human disease. …”
Publicado 2015
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219“…In the present study, we have conducted genome-wide association mapping in Drosophila melanogaster to identify the genetic basis for individual variation in resistance, and for variation in immunological sensitivity to diet (genotype-by-environment interaction, or GxE). …”
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220por Arya, Gunjan H., Magwire, Michael M., Huang, Wen, Serrano-Negron, Yazmin L., Mackay, Trudy F.C., Anholt, Robert R.H.“…To explore the genetic basis of variation in olfactory perception, we measured behavioral responses to 14 chemically diverse naturally occurring odorants in 260400 flies from 186 lines of the Drosophila melanogaster Genetic Reference Panel, a population of inbred wild-derived lines with sequenced genomes. …”
Publicado 2015
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