“…In two adjacent studies, we explored how dietary spermidine supplementation enhances eEF5/EIF5A hypusination, cerebral mitochondrial function and cognition in aging Drosophila melanogaster and mice.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, we use the eye disc of Drosophila melanogaster as a model to explore the mechanisms involved in promoting glial cell response after neuronal cell death induction. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…How a receptor gene is selected, from among a large repertoire in the genome, to be expressed in a particular neuron is an outstanding question. Focusing on Drosophila melanogaster, where most investigations have been performed, but incorporating recent insights from other insect species, we review the multilevel regulatory mechanisms of olfactory receptor expression. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, we searched for LARKS in the proteomes of six model organisms: Homo sapiens, Drosophila melanogaster, Plasmodium falciparum, Saccharomyces cerevisiae, Mycobacterium tuberculosis, and Escherichia coli to gain an understanding of the distribution of LARKS in the proteomes of various species. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, we replaced the entire Drosophila melanogaster proboscipedia (pb) Hox locus, which controls the development of the proboscis and maxillary palps, with that from Drosophila mimica, a related species with highly modified mouthparts. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RNAi-mediated cardiomyocyte-specific knockdown of CLS in Drosophila melanogaster resulted in marked cardiac dilatation, severe impairment of systolic performance, and slower diastolic filling velocity assessed by fluorescence-based heart imaging. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Such acts are often associated with ethanol consumption. The Drosophila melanogaster model system, which has long been used to study how ethanol affects the nervous system and behavior, has also been used to study the molecular origins of aggression. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The biological process of the circadian rhythm was first studied in Drosophila melanogaster and is well understood. Their locomotor activity gradually increases before the light is switched on and off, a phenomenon called anticipation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, we report that transgenic ablation of germ cells in late development or early adulthood in Drosophila melanogaster causes elevated baseline expression and increased induction of Toll and Imd immune genes upon bacterial infection, as compared to fertile flies with an intact germline. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Surprisingly, the application of SNA revealed that Drosophila melanogaster, previously considered a solitary organism, displays group dynamics and that the structure of group life is inherited. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…During the last decade, Drosophila melanogaster has demonstrated to be an excellent model to tackle some of the open questions in the field of metabolism and development of endocrine/metabolic organs. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In comparison, alternative models (e.g. models using Caenorhabditis elegans, Drosophila melanogaster or G. mellonella) were cheap, simple to use and not limited by ethical regulation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This is largely due to population heterogeneity which entails a requirement for large samples. Drosophila melanogaster exhibits similar psychostimulant responses to humans, a high degree of gene conservation, and allow performance of behavioral assays in a large population. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We investigated this using the fruit fly Drosophila melanogaster, an organism long-used to study the mechanistic basis of learning and memory. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In Drosophila melanogaster, loss of regenerative capacity in wing imaginal discs coincides with an increase in systemic levels of the steroid hormone ecdysone, a key coordinator of their developmental progression. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…How initiator IDRs facilitate LLPS and maintain compositional specificity is unknown. Here, using Drosophila melanogaster (Dm) Cdt1 as a model initiation factor, we show that phase separation results from a synergy between electrostatic DNA-bridging interactions and hydrophobic inter-IDR contacts. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Recent discoveries in the fruit fly Drosophila melanogaster revealed that insect steroid hormones or ecdysteroids are incorporated into cells through a membrane transporter named Ecdysone Importer (EcI), which may become a novel target for manipulating steroid hormone signaling in insects. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Among the various model systems, Drosophila melanogaster has several advantages for modeling human neurodegenerative diseases. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This review briefly touches upon studies on the genetically tractable model organisms of Caenorhabditis elegans and Drosophila melanogaster about the action of specific developmental neurotoxicants. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…From our knowledge of RDG network regulation in Drosophila melanogaster, we hypothesize that orthologs of Pax6, eyegone, Wnt genes, hh, dpp, and atonal could play important roles in controlling eye development in spiders. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso