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  1. 4861
    “…Recent studies of tethered Drosophila melanogaster (fruit fly) in a virtual reality setting showed that the head direction is encoded in the form of an activity bump, i.e., localized neural activity, in the torus-shaped ellipsoid body (EB). …”
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    Coordination through Inhibition: Control of Stabilizing and Updating Circuits in Spatial Orientation Working Memory
  2. 4862
    “…Here, we generate a collection of split-GAL4 lines that provides precise genetic targeting of 138 different SEZ cell types in adult Drosophila melanogaster, comprising approximately one third of all SEZ neurons. …”
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    Classification and genetic targeting of cell types in the primary taste and premotor center of the adult Drosophila brain
  3. 4863
    “…Defects in lipolysis can be modeled in Drosophila melanogaster through genetic manipulations of brummer (bmm), which encodes a triglyceride lipase orthologous to mammalian Adipose Triglyceride Lipase. …”
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    Physiological and metabolomic consequences of reduced expression of the Drosophila brummer triglyceride Lipase
  4. 4864
    “…Here, we investigated this aspect using the Drosophila melanogaster Sigma virus. It is particularly relevant in the genome/TE interaction given its tropism to ovaries, which is the organ displaying the more sophisticated TE control pathways. …”
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    Infections by Transovarially Transmitted DMelSV in Drosophila Have No Impact on Ovarian Transposable Element Transcripts but Increase Their Amounts in the Soma
  5. 4865
    “…Using population genomic data, we inferred DFE correlations of populations in humans, Drosophila melanogaster, and wild tomatoes. In these species, we found that the overall correlation of the joint DFE was inversely related to genetic differentiation. …”
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    Inferring Genome-Wide Correlations of Mutation Fitness Effects between Populations
  6. 4866
    “…Pan-neuronal expression of Aβ(42)(Arctic) peptides in Drosophila melanogaster results in learning and memory defects. …”
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    Dopamine, sleep, and neuronal excitability modulate amyloid-β–mediated forgetting in Drosophila
  7. 4867
    “…The Tribolium castaneum (Coleoptera, Tenebrionidae) OBPs encoded by the gene pair TcasOBP9A and TcasOBP9B represent the closest homologs to the well-studied Drosophila melanogaster OBP Lush (DmelOBP76a), which mediates pheromone reception. …”
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    Mutually Exclusive Expression of Closely Related Odorant-Binding Proteins 9A and 9B in the Antenna of the Red Flour Beetle Tribolium castaneum
  8. 4868
    “…We faced such a phenomenon when studying the fertility level in two wild type Drosophila melanogaster strains. For fertility analysis, 50 newly emerged females and 50 males of each strain under study were transferred to fresh medium daily within 10 days. …”
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    A Link between Atmospheric Pressure and Fertility of Drosophila Laboratory Strains
  9. 4869
    “…The beta-blocker drug labetalol, which inhibits binding of catecholamine neurotransmitters to adrenergic receptors, reduces intestinal permeability in a rat TBI model. Using a Drosophila melanogaster TBI model, we previously found a strong positive correlation between intestinal permeability and mortality within 24 hours of TBI in a standard laboratory line (w(1118)) and across genetically diverse inbred lines from the Drosophila Genetic Reference Panel (DGRP). …”
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    Beta-blockers reduce intestinal permeability and early mortality following traumatic brain injury in Drosophila
  10. 4870
    “…Over the past few decades, the model organism Drosophila melanogaster has been crucial in identifying cancer‐related genes and pathways and elucidating mechanisms underlying growth regulation in development. …”
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    Tumor models in various Drosophila tissues
  11. 4871
    “…Here, we found that the ho mRNA level oscillates in the brain of Drosophila melanogaster with two minima at the beginning of the day and night. …”
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    Regulation of Heme Oxygenase and Its Cross-Talks with Apoptosis and Autophagy under Different Conditions in Drosophila
  12. 4872
    “…Here we report that in a natural population of Drosophila melanogaster, individuals that are infected with Wolbachia are less likely to be infected by viruses. …”
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    Wolbachia reduces virus infection in a natural population of Drosophila
  13. 4873
    “…Here, we review apicobasal crosstalk of two well-established models of membrane remodelling taking place during Drosophila melanogaster embryogenesis: amnioserosa cell shape oscillations during dorsal closure and subcellular tube formation in tracheal cells. …”
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    Crosstalk between basal extracellular matrix adhesion and building of apical architecture during morphogenesis
  14. 4874
    “…Although many genes that regulate nuclear movement have been identified, the mechanisms by which these genes act are not known. Using Drosophila melanogaster muscle development as a model system and a combination of live-embryo microscopy and laser ablation of nuclei, we have found that clustered nuclei encompass at least two phenotypes that are caused by distinct mechanisms. …”
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    Ensconsin-dependent changes in microtubule organization and LINC complex–dependent changes in nucleus–nucleus interactions result in quantitatively distinct myonuclear positioning defects
  15. 4875
    “…In this study, we investigated the effects of dietary supplementation with 5‐ALA and SFC (5‐ALA/SFC) on the healthspan and life span of Drosophila  melanogaster. Adult Drosophila fruit flies were fed cornmeal food containing various concentrations of 5‐ALA/SFC. …”
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    5‐Aminolevulinic acid and sodium ferrous citrate ameliorate muscle aging and extend healthspan in Drosophila
  16. 4876
    “…During the maternal-to-zygotic transition (MZT), which encompasses the earliest stages of animal embryogenesis, a subset of maternally supplied gene products is cleared, thus permitting activation of zygotic gene expression. In the Drosophila melanogaster embryo, the RNA-binding protein Smaug (SMG) plays an essential role in progression through the MZT by translationally repressing and destabilizing a large number of maternal mRNAs. …”
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    The F-box protein Bard (CG14317) targets the Smaug RNA-binding protein for destruction during the Drosophila maternal-to-zygotic transition
  17. 4877
    “…We previously identified TRMT2A as a strong modifier of polyQ-induced toxicity in an unbiased large-scale screen in Drosophila melanogaster. This work aimed at identifying and validating pharmacological TRMT2A inhibitors as treatment opportunities for polyQ diseases in humans. …”
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    Small-molecule modulators of TRMT2A decrease PolyQ aggregation and PolyQ-induced cell death
  18. 4878
    por Lee, Sang Hyuk, Kim, Eun Young
    Publicado 2021
    “…Given that diet can influence many aspects of sleep, we investigated whether a high-sucrose diet (HSD) affected aging-induced sleep fragmentation using the fruit fly, Drosophila melanogaster. Drosophila is a valuable model for studying sleep due to its genetic tractability and many similarities with mammalian sleep. …”
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    Short-term maintenance on a high-sucrose diet alleviates aging-induced sleep fragmentation in drosophila
  19. 4879
    “…This work aimed to study the action of individual VOCs on the bacteria Agrobacterium tumefaciens, Arabidopsis thaliana plants, and fruit flies Drosophila melanogaster. VOCs used in the work included ketones, alcohols, and terpenes. …”
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    The Effect of Volatile Organic Compounds on Different Organisms: Agrobacteria, Plants and Insects
  20. 4880
    “…We have analyzed mutagenesis in Xenopus laevis and Drosophila melanogaster early embryos. We report the occurrence of a high mutation rate in Xenopus and show that it is dependent upon the translesion DNA synthesis (TLS) master regulator Rad18. …”
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    Translesion DNA synthesis-driven mutagenesis in very early embryogenesis of fast cleaving embryos
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