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4861por Han, Rui, Huang, Hsuan-Pei, Chuang, Chia-Lung, Yen, Hung-Hsiu, Kao, Wei-Tse, Chang, Hui-Yun, Lo, Chung-Chuan“…Recent studies of tethered Drosophila melanogaster (fruit fly) in a virtual reality setting showed that the head direction is encoded in the form of an activity bump, i.e., localized neural activity, in the torus-shaped ellipsoid body (EB). …”
Publicado 2021
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4862“…Here, we generate a collection of split-GAL4 lines that provides precise genetic targeting of 138 different SEZ cell types in adult Drosophila melanogaster, comprising approximately one third of all SEZ neurons. …”
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4863por Nazario-Yepiz, Nestor O., Fernández Sobaberas, Jaime, Lyman, Roberta, Campbell, Marion R., Shankar, Vijay, Anholt, Robert R. H., Mackay, Trudy F. C.“…Defects in lipolysis can be modeled in Drosophila melanogaster through genetic manipulations of brummer (bmm), which encodes a triglyceride lipase orthologous to mammalian Adipose Triglyceride Lipase. …”
Publicado 2021
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4864por Roy, Marlène, Viginier, Barbara, Mayeux, Camille A, Ratinier, Maxime, Fablet, Marie“…Here, we investigated this aspect using the Drosophila melanogaster Sigma virus. It is particularly relevant in the genome/TE interaction given its tropism to ovaries, which is the organ displaying the more sophisticated TE control pathways. …”
Publicado 2021
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4865por Huang, Xin, Fortier, Alyssa Lyn, Coffman, Alec J, Struck, Travis J, Irby, Megan N, James, Jennifer E, León-Burguete, José E, Ragsdale, Aaron P, Gutenkunst, Ryan N“…Using population genomic data, we inferred DFE correlations of populations in humans, Drosophila melanogaster, and wild tomatoes. In these species, we found that the overall correlation of the joint DFE was inversely related to genetic differentiation. …”
Publicado 2021
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4866por Kaldun, Jenifer C., Lone, Shahnaz R., Humbert Camps, Ana M., Fritsch, Cornelia, Widmer, Yves F., Stein, Jens V., Tomchik, Seth M., Sprecher, Simon G.“…Pan-neuronal expression of Aβ(42)(Arctic) peptides in Drosophila melanogaster results in learning and memory defects. …”
Publicado 2021
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4867por Montino, Alice, Balakrishnan, Karthi, Dippel, Stefan, Trebels, Björn, Neumann, Piotr, Wimmer, Ernst A.“…The Tribolium castaneum (Coleoptera, Tenebrionidae) OBPs encoded by the gene pair TcasOBP9A and TcasOBP9B represent the closest homologs to the well-studied Drosophila melanogaster OBP Lush (DmelOBP76a), which mediates pheromone reception. …”
Publicado 2021
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4868“…We faced such a phenomenon when studying the fertility level in two wild type Drosophila melanogaster strains. For fertility analysis, 50 newly emerged females and 50 males of each strain under study were transferred to fresh medium daily within 10 days. …”
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4869por Scharenbrock, Amanda R, Katzenberger, Rebeccah J, Fischer, Megan C, Ganetzky, Barry, Wassarman, David A“…The beta-blocker drug labetalol, which inhibits binding of catecholamine neurotransmitters to adrenergic receptors, reduces intestinal permeability in a rat TBI model. Using a Drosophila melanogaster TBI model, we previously found a strong positive correlation between intestinal permeability and mortality within 24 hours of TBI in a standard laboratory line (w(1118)) and across genetically diverse inbred lines from the Drosophila Genetic Reference Panel (DGRP). …”
Publicado 2021
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4870“…Over the past few decades, the model organism Drosophila melanogaster has been crucial in identifying cancer‐related genes and pathways and elucidating mechanisms underlying growth regulation in development. …”
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4871por Al L. Abaquita, Terence, Damulewicz, Milena, Bhattacharya, Debarati, Pyza, Elżbieta“…Here, we found that the ho mRNA level oscillates in the brain of Drosophila melanogaster with two minima at the beginning of the day and night. …”
Publicado 2021
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4872por Cogni, Rodrigo, Ding, Shuai Dominique, Pimentel, André C., Day, Jonathan P., Jiggins, Francis M.“…Here we report that in a natural population of Drosophila melanogaster, individuals that are infected with Wolbachia are less likely to be infected by viruses. …”
Publicado 2021
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4873“…Here, we review apicobasal crosstalk of two well-established models of membrane remodelling taking place during Drosophila melanogaster embryogenesis: amnioserosa cell shape oscillations during dorsal closure and subcellular tube formation in tracheal cells. …”
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4874por Collins, Mary Ann, Coon, L. Alexis, Thomas, Riya, Mandigo, Torrey R., Wynn, Elizabeth, Folker, Eric S.“…Although many genes that regulate nuclear movement have been identified, the mechanisms by which these genes act are not known. Using Drosophila melanogaster muscle development as a model system and a combination of live-embryo microscopy and laser ablation of nuclei, we have found that clustered nuclei encompass at least two phenotypes that are caused by distinct mechanisms. …”
Publicado 2021
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4875por Nozawa, Naoko, Noguchi, Marie, Shinno, Kanako, Tajima, Maki, Aizawa, Shingo, Saito, Taro, Asada, Akiko, Ishii, Takuya, Ishizuka, Masahiro, Iijima, Koichi M., Ando, Kanae“…In this study, we investigated the effects of dietary supplementation with 5‐ALA and SFC (5‐ALA/SFC) on the healthspan and life span of Drosophila melanogaster. Adult Drosophila fruit flies were fed cornmeal food containing various concentrations of 5‐ALA/SFC. …”
Publicado 2021
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4876por Cao, Wen Xi, Karaiskakis, Angelo, Lin, Sichun, Angers, Stephane, Lipshitz, Howard D“…During the maternal-to-zygotic transition (MZT), which encompasses the earliest stages of animal embryogenesis, a subset of maternally supplied gene products is cleared, thus permitting activation of zygotic gene expression. In the Drosophila melanogaster embryo, the RNA-binding protein Smaug (SMG) plays an essential role in progression through the MZT by translationally repressing and destabilizing a large number of maternal mRNAs. …”
Publicado 2021
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4877por Margreiter, Michael A, Witzenberger, Monika, Wasser, Yasmine, Davydova, Elena, Janowski, Robert, Metz, Jonas, Habib, Pardes, Sahnoun, Sabri E.M., Sobisch, Carina, Poma, Benedetta, Palomino-Hernandez, Oscar, Wagner, Mirko, Carell, Thomas, Jon Shah, N., Schulz, Jörg B., Niessing, Dierk, Voigt, Aaron, Rossetti, Giulia“…We previously identified TRMT2A as a strong modifier of polyQ-induced toxicity in an unbiased large-scale screen in Drosophila melanogaster. This work aimed at identifying and validating pharmacological TRMT2A inhibitors as treatment opportunities for polyQ diseases in humans. …”
Publicado 2021
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4878“…Given that diet can influence many aspects of sleep, we investigated whether a high-sucrose diet (HSD) affected aging-induced sleep fragmentation using the fruit fly, Drosophila melanogaster. Drosophila is a valuable model for studying sleep due to its genetic tractability and many similarities with mammalian sleep. …”
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4879por Sidorova, Daria E., Plyuta, Vladimir A., Padiy, Darya A., Kupriyanova, Evgeniya V., Roshina, Natalia V., Koksharova, Olga A., Khmel, Inessa A.“…This work aimed to study the action of individual VOCs on the bacteria Agrobacterium tumefaciens, Arabidopsis thaliana plants, and fruit flies Drosophila melanogaster. VOCs used in the work included ketones, alcohols, and terpenes. …”
Publicado 2021
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4880por Lo Furno, Elena, Busseau, Isabelle, Aze, Antoine, Lorenzi, Claudio, Saghira, Cima, Danzi, Matt C, Zuchner, Stephan, Maiorano, Domenico“…We have analyzed mutagenesis in Xenopus laevis and Drosophila melanogaster early embryos. We report the occurrence of a high mutation rate in Xenopus and show that it is dependent upon the translesion DNA synthesis (TLS) master regulator Rad18. …”
Publicado 2021
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