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4981“…Recently, CTCF joined Su(Hw), Zw5, BEAF32 and GAGA factor as a protein associated with insulator activity in the fruitfly, Drosophila melanogaster. To date, no known insulators have been described in mosquitoes. …”
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4982por Sharabiani, Mansour Taghavi Azar, Siermala, Markku, Lehtinen, Tommi O, Vihinen, Mauno“…The method was applied to investigate microarray datasets for different cell types, organisms and processes, including human B and T cell stimulation, Drosophila melanogaster life span, and Saccharomyces cerevisiae cell cycle. …”
Publicado 2005
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4983por Ferree, Patrick M, Frydman, Horacio M, Li, Jennifer M, Cao, Jian, Wieschaus, Eric, Sullivan, William“…To investigate the role of the host cytoskeleton in the maternal transmission of the endoparasitic bacteria Wolbachia, we have characterized their distribution in the female germ line of Drosophila melanogaster. In the germarium, Wolbachia are distributed to all germ cells of the cyst, establishing an early infection in the cell destined to become the oocyte. …”
Publicado 2005
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4984“…RESULTS: We examine the relationship between intron length and levels of evolutionary constraint by analyzing inter-specific divergence at 225 intron fragments in Drosophila melanogaster and Drosophila simulans, sampled from a broad distribution of intron lengths. …”
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4985por True, John R, Yeh, Shu-Dan, Hovemann, Bernhard T, Kemme, Tobias, Meinertzhagen, Ian A, Edwards, Tara N, Liou, Shian-Ren, Han, Qian, Li, Jianyong“…Here we report that the classical Drosophila melanogaster locus tan encodes a novel enzyme required for two very different cellular functions: hydrolysis of N-β-alanyl dopamine (NBAD) to dopamine during cuticular melanization, and hydrolysis of carcinine to histamine in the metabolism of photoreceptor neurotransmitter. …”
Publicado 2005
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4986por Stapleton, Mark, Carlson, Joe, Brokstein, Peter, Yu, Charles, Champe, Mark, George, Reed, Guarin, Hannibal, Kronmiller, Brent, Pacleb, Joanne, Park, Soo, Wan, Ken, Rubin, Gerald M, Celniker, Susan E“…Providing this resource to the Drosophila melanogaster research community has been a long-term goal of the Berkeley Drosophila Genome Project. …”
Publicado 2002
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4987“…In animals, most small nuclear RNAs (snRNAs) are synthesized by RNA polymerase II (Pol II), but U6 snRNA is synthesized by RNA polymerase III (Pol III). In Drosophila melanogaster, the promoters for the Pol II-transcribed snRNA genes consist of ∼21 bp PSEA and ∼8 bp PSEB. …”
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4988“…We found evidence for a role of transcripts from these ancestral remnants in the natural epigenetic protection of the Drosophila melanogaster genome against the deleterious effects of new invasions by functional I-factors. …”
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4989“…Using intracellular recordings from the intact retinas of four flies, Drosophila melanogaster, D. virilis, Calliphora vicina, and Sarcophaga carnaria, we measured the rates at which homologous R1–6 photoreceptors of these species transmit information from the same stimuli and estimated the energy they consumed. …”
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4990“…The five algorithms were then compared by fixing parameters settings, and the analysis was extended to three other genomes (Saccharomyces cerevisiae, Neurospora crassa and Drosophila melanogaster) spanning a wide range of size and structure. …”
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4991por Gilfillan, Gregor D., König, Cornelia, Dahlsveen, Ina K., Prakoura, Nicky, Straub, Tobias, Lamm, Rosemarie, Fauth, Torsten, Becker, Peter B.“…Fine-tuning of X chromosomal gene expression in Drosophila melanogaster involves the selective interaction of the Dosage Compensation Complex (DCC) with the male X chromosome, in order to increase the transcription of many genes. …”
Publicado 2007
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4992por Dawson-Scully, Ken, Armstrong, Gary A.B., Kent, Clement, Robertson, R. Meldrum, Sokolowski, Marla B.“…We link natural variation in the thermotolerance of neural function and behavior in Drosophila melanogaster to the foraging gene (for, which encodes a cGMP-dependent protein kinase (PKG)) as well as to its downstream target, protein phosphatase 2A (PP2A). …”
Publicado 2007
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4993por Bodenmiller, Bernd, Malmstrom, Johan, Gerrits, Bertran, Campbell, David, Lam, Henry, Schmidt, Alexander, Rinner, Oliver, Mueller, Lukas N, Shannon, Paul T, Pedrioli, Patrick G, Panse, Christian, Lee, Hoo-Keun, Schlapbach, Ralph, Aebersold, Ruedi“…Here, we present PhosphoPep, a database containing more than 10 000 unique high-confidence phosphorylation sites mapping to nearly 3500 gene models and 4600 distinct phosphoproteins of the Drosophila melanogaster Kc167 cell line. This constitutes the most comprehensive phosphorylation map of any single source to date. …”
Publicado 2007
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4994por Kim, Hwajin, Ling, Shuo-Chien, Rogers, Gregory C., Kural, Comert, Selvin, Paul R., Rogers, Stephen L., Gelfand, Vladimir I.“…To examine the role of microtubule binding by p150(glued), we replaced the wild-type p150(glued) in Drosophila melanogaster S2 cells with mutant ΔN-p150 lacking residues 1–200, which is unable to bind microtubules. …”
Publicado 2007
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4995Gawky is a component of cytoplasmic mRNA processing bodies required for early Drosophila developmentpor Schneider, Mary D., Najand, Nima, Chaker, Sana, Pare, Justin M., Haskins, Julie, Hughes, Sarah C., Hobman, Tom C., Locke, John, Simmonds, Andrew J.“…We have characterized the single Drosophila melanogaster homologue of the human GW182 protein family, which we have named Gawky (GW). …”
Publicado 2006
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4996por Kunisaki, Yuya, Nishikimi, Akihiko, Tanaka, Yoshihiko, Takii, Ryosuke, Noda, Mayuko, Inayoshi, Ayumi, Watanabe, Ken-ichi, Sanematsu, Fumiyuki, Sasazuki, Takehiko, Sasaki, Takehiko, Fukui, Yoshinori“…We show that DOCK2, which is a mammalian homologue of Caenorhabditis elegans CED-5 and Drosophila melanogaster Myoblast City, regulates motility and polarity during neutrophil chemotaxis. …”
Publicado 2006
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4997por Witzel, Sabine, Zimyanin, Vitaly, Carreira-Barbosa, Filipa, Tada, Masazumi, Heisenberg, Carl-Philipp“…It is known that Wnt11 functionally interacts with several signaling components, the homologues of which control planar cell polarity in Drosophila melanogaster. Although in D. melanogaster these components are thought to polarize cells by asymmetrically localizing at the plasma membrane, it is not yet clear whether their subcellular localization plays a similarly important role in vertebrates. …”
Publicado 2006
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4998por Mirouse, Vincent, Swick, Lance L., Kazgan, Nevzat, St Johnston, Daniel, Brenman, Jay E.“…We describe the identification of mutations in the single Drosophila melanogaster AMPK catalytic subunit AMPKα. Surprisingly, ampkα mutant epithelial cells lose their polarity and overproliferate under energetic stress. …”
Publicado 2007
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4999“…We perform extensive tests on orthologous CRMs from two moderately diverged species Drosophila melanogaster and D. mojavensis, to demonstrate the advantages of the new approach. …”
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5000“…Near the time of pupation, autofluorescent kynurenine globules appear in the cells in the anterior region of the fatbody of Drosophila melanogaster. It has been reported previously that kynurenine synthesis may be induced in an additional group of fat cells by feeding the precursor tryptophan to Drosophila larvae, and that this induction of kynurenine production viewed within the fat cells is correlated with an increase in tryptophan pyrrolase activity. …”
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