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5241por Brewer-Jensen, Paul, Wilson, Carrie B., Abernethy, John, Mollison, Lonna, Card, Samantha, Searles, Lillie L.“…Here, we present evidence that the suppressor of sable [su(s)] regulatory pathway of Drosophila melanogaster plays a role in this process. We previously showed that Su(s) promotes exosome-mediated degradation of transcripts from endogenous repeated elements at an Hsp70 locus (Hsp70-αβ elements). …”
Publicado 2016
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5242“…Dusky-like (Dyl) is associated with the morphogenesis of embryonic denticle, adult sensory bristle and wing hair in Drosophila melanogaster. And whether Dyl involved in insect post-embryonic development and its signal transduction are poorly understood. …”
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5243por Jiang, Jingjing, Chan, Adriano, Ali, Sameh, Saha, Arindam, Haushalter, Kristofer J., Lam, Wai-Ling Macrina, Glasheen, Megan, Parker, James, Brenner, Matthew, Mahon, Sari B., Patel, Hemal H., Ambasudhan, Rajesh, Lipton, Stuart A., Pilz, Renate B., Boss, Gerry R.“…The vitamin B(12) analog cobinamide reversed the cellular toxicity of sulfide, and rescued Drosophila melanogaster and mice from lethal exposures of hydrogen sulfide gas. …”
Publicado 2016
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5244por Semmens, Dean C., Mirabeau, Olivier, Moghul, Ismail, Pancholi, Mahesh R., Wurm, Yannick, Elphick, Maurice R.“…The deuterostomian invertebrates are of particular interest in this regard because they occupy an ‘intermediate' position in animal phylogeny, bridging the gap between the well-studied model protostomian invertebrates (e.g. Drosophila melanogaster, Caenorhabditis elegans) and the vertebrates. …”
Publicado 2016
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5245“…In the case of 20-hydroxyecdysone (ecdysone) in Drosophila melanogaster, these trajectories range from apoptosis to immortalization. …”
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5246“…Here we employ an alternative, broad spectrum methyltransferase, Drosophila melanogaster Juvenile Hormone Acid O-Methyltransferase (DmJHAMT). …”
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5247por Galenza, Anthony, Hutchinson, Jaclyn, Campbell, Shelagh D., Hazes, Bart, Foley, Edan“…Here we show that individual modifications to a completely defined diet markedly impact multiple aspects of organism wellbeing in Drosophila melanogaster. Through a longitudinal survey of several diets we demonstrate that increased levels of dietary glucose significantly improve longevity and immunity in adult Drosophila. …”
Publicado 2016
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5248“…Genetic studies of Drosophila melanogaster have provided a paradigm for RNA interference (RNAi) in arthropods, in which the microRNA and antiviral pathways are each mediated by a single Argonaute (Ago1 and Ago2) and germline suppression of transposable elements is mediated by a trio of Piwi-subfamily Argonaute proteins (Ago3, Aub, and Piwi). …”
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5249“…Enzyme-Linked Immunosorbent Assays indicated that protein levels were 4.61 ng g(-1) dry weight in fruit flies (Drosophila melanogaster) fed with the transgenic cabbage and 1.86 ng g(-1) dry weight in the wolf spiders that preyed upon them. …”
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5250por King, Lanikea B., Koch, Marta, Murphy, Keith R., Velazquez, Yoheilly, Ja, William W., Tomchik, Seth M.“…The nf1-encoded neurofibromin protein (Nf1) exhibits high conservation, from the common fruit fly, Drosophila melanogaster, to humans. Drosophila provides a powerful platform to investigate the signaling cascades upstream and downstream of Nf1, and the fly model exhibits similar behavioral phenotypes to mammalian models. …”
Publicado 2016
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5251“…The 5-HT(1B)-null Drosophila melanogaster mutants showed higher mortality than controls when infected with bacteria, due to their decreased phagocytotic ability. …”
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5252por Louie, Alexander, Song, Kyung Han, Hotson, Alejandra, Thomas Tate, Ann, Schneider, David S.“…Using a model experimental system in which we challenged Drosophila melanogaster with the pathogen Listeria monocytogenes, we tested this framework, finding that microbe growth, the immune response, and disease tolerance were all well represented by sigmoid models. …”
Publicado 2016
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5253por Hueston, Catherine E., Olsen, Douglas, Li, Qingyun, Okuwa, Sumie, Peng, Bo, Wu, Jianni, Volkan, Pelin Cayirlioglu“…Here, we describe two modes of regulation that coordinate the sensory identities of Drosophila melanogaster olfactory receptor neurons (ORNs) involved in sex-specific behaviors with the sex-specific behavioral circuit identity marker fruitless (fru). …”
Publicado 2016
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5254“…In the cockroach Periplaneta americana, thermoreceptor neurons on antennae and thermosensory interneurons in the antennal lobe have been characterized electrophysiologically, and recent studies using advanced transgenic technologies in the fruit fly Drosophila melanogaster have added much to the knowledge of these neurons, enabling us to discuss common principles of thermosensory processing systems in insects. …”
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5255por Weijers, Rob N. M.“…Against the background of these processes, we review recently published experimental phospholipid data obtained from Drosophila melanogaster and from human erythrocytes of controls and patients with type 2 diabetes, with and without retinopathy, along the way free fatty acids interfere with eye and kidney function in patients with type 2 diabetes and give rise to endoplasmic reticulum stress, reduced insulin sensitivity, and ischemia.…”
Publicado 2016
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5256“…Here we developed a novel mitonuclear epistasis model, using selected strains of the Drosophila Genetic Reference Panel (DGRP) and mitochondrial genomes from within Drosophila melanogaster and D. simulans to test the hypothesis that mtDNA × nDNA interactions influence fitness. …”
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5257por Bae, Ji-Eun, Bang, Sunhoe, Min, Soohong, Lee, Sang-Hyup, Kwon, Soon-Hwan, Lee, Youngseok, Lee, Yong-Ho, Chung, Jongkyeong, Chae, Kwon-Seok“…RESULTS: Using Drosophila melanogaster as a model organism, we showed that geomagnetic field (GMF) induces positive geotaxis and antagonizes negative gravitaxis. …”
Publicado 2016
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5258por Mellert, David J., Williamson, W. Ryan, Shirangi, Troy R., Card, Gwyneth M., Truman, James W.“…To investigate the causes and potential consequences of wiring variation in Drosophila melanogaster, we focused on a hemilineage of ventral nerve cord interneurons that exhibits morphological variability. …”
Publicado 2016
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5259por De Lella Ezcurra, Ana Laura, Bertolin, Agustina Paola, Kim, Kevin, Katz, Maximiliano Javier, Gándara, Lautaro, Misra, Tvisha, Luschnig, Stefan, Perrimon, Norbert, Melani, Mariana, Wappner, Pablo“…To identify microRNAs required for maximal HIF activity, we conducted an overexpression screen in Drosophila melanogaster, evaluating the induction of a HIF transcriptional reporter. miR-190 overexpression enhanced HIF-dependent biological responses, including terminal sprouting of the tracheal system, while in miR-190 loss of function embryos the hypoxic response was impaired. …”
Publicado 2016
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5260por Overend, Gayle, Luo, Yuan, Henderson, Louise, Douglas, Angela E., Davies, Shireen A., Dow, Julian A. T.“…The gut of Drosophila melanogaster includes a proximal acidic region (~pH 2), however the genome lacks the H(+)/K(+) ATPase characteristic of the mammalian gastric parietal cell, and the molecular mechanisms of acid generation are poorly understood. …”
Publicado 2016
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