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5501por Chongtham, Anjalika, Yoo, Jung Hyun, Chin, Theodore M., Akingbesote, Ngozi D., Huda, Ainul, Marsh, J. Lawrence, Khoshnan, Ali“…Here, we investigated whether gut bacteria affect the progression of Huntington’s disease (HD) in transgenic Drosophila melanogaster (fruit fly) models expressing full-length or N-terminal fragments of human mutant huntingtin (HTT) protein. …”
Publicado 2022
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5502por Karki, Prajwal, Carney, Travis D, Maracci, Cristina, Yatsenko, Andriy S, Shcherbata, Halyna R, Rodnina, Marina V“…Here, we quantify TR of several candidate genes in Drosophila melanogaster and characterize the regulation of TR in the large Maf transcription factor Traffic jam (Tj). …”
Publicado 2021
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5503“…In this study, BmVps13d protein shared 30.84% and 34.35% identity with that of in Drosophila melanogaster and Homo. sapiens, respectively. The expressions of BmVps13d were significantly higher in the midgut and silk gland of JS (high silk yield) than in that of L10 (low silk yield). …”
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5504“…We will focus on Drosophila melanogaster CIPN models that are genetically amenable and accessible to study neuronal interactions with the local environment in vivo. …”
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5505“…As an example, a ranking of the average affinity of antidepressants and other ligands to the Drosophila melanogaster dopamine transporter (dDAT) was presented. …”
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5506“…Selenophosphate synthetase 1 (SPS1) is an essential gene for the cell growth and embryogenesis in Drosophila melanogaster. We have previously reported that SPS1 deficiency stimulates the expression of genes responsible for the innate immune system, including antimicrobial peptides (AMPs), in Drosophila S2 cells. …”
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5507por Rodríguez Pescador, Alonso, Gutiérrez Romero, Lucía, Blanco-González, Elisa, Montes-Bayón, María, Sierra, L. María“…In vivo genotoxicity was further studied in larvae from Drosophila melanogaster, using the eye-SMART test. The obtained results showed that FeAT-NPs were genotoxic only with the two highest tested concentrations (2 and 5 mmol·L(−1) of Fe) in surface treatments. …”
Publicado 2022
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5508“…Here, we compared this TE-mediated local enrichment of repressive marks, or ‘the epigenetic effect of TEs’, in six species in the Drosophila melanogaster subgroup to dissect step-by-step the role of such effect in determining genomic TE abundance. …”
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5509por Shirasaki, Riku, Tanaka, Ryoya, Takekata, Hiroki, Shimada, Takashi, Ishikawa, Yuki, Kamikouchi, Azusa“…Here, we compared the group formation processes of two Drosophilinae fly species, Colocasiomyia alocasiae and Drosophila melanogaster, which form dense and sparse groups, respectively. …”
Publicado 2022
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5510por Yang, Shipei, Li, Xu, Xiu, Minghui, Dai, Yuting, Wan, Shengfang, Shi, Yan, Liu, Yongqi, He, Jianzheng“…Here, we employed Drosophila melanogaster as a model organism to investigate the protective effect of Flos Puerariae extract (FPE) against sodium dodecyl sulfate (SDS)-induced intestinal injury. …”
Publicado 2022
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5511por Tahanzadeh, Navid, Knop, Mirjam, Seidler, Yvonne, Dirndorfer, Sebastian, Lürsen, Kai, Bruchhaus, Iris, Lang, Roman, Rimbach, Gerald, Roeder, Thomas“…For this purpose, we used the fruit fly Drosophila melanogaster as a model. The experiments showed that small amounts of Eisenia extract can extend lifespan by up to 40%. …”
Publicado 2022
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5512por Maaroufi, Houda Ouns, Pauchova, Lucie, Lin, Yu-Hsien, Wu, Bulah Chia-Hsiang, Rouhova, Lenka, Kucerova, Lucie, Vieira, Ligia Cota, Renner, Marek, Sehadova, Hana, Hradilova, Miluse, Zurovec, Michal“…Here, we investigated the role of the Drosophila melanogaster cnt1 gene, which is specifically expressed in the testes. …”
Publicado 2022
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5513por Linnemannstöns, Karen, Karuna M, Pradhipa, Witte, Leonie, Choezom, Dolma, Honemann‐Capito, Mona, Lagurin, Alex Simon, Schmidt, Chantal Vanessa, Shrikhande, Shreya, Steinmetz, Lara‐Kristin, Wiebke, Möbius, Lenz, Christof, Gross, Julia Christina“…Here, we present an in vivo model to study EV secretion using the fat body and the haemolymph of the fruit fly, Drosophila melanogaster. The system makes use of tissue‐specific EV labelling and is amenable to genetic modification by RNAi. …”
Publicado 2022
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5514por Howard, John D., Beghyn, Myriam, Dewulf, Nathalie, De Vos, Yves, Philips, Annelies, Portwood, David, Kilby, Peter M., Oliver, Duncan, Maddelein, Wendy, Brown, Stephen, Dickman, Mark J.“…Phosphorothioate-modified and 2′-fluoro-modified dsRNA also demonstrated increased resistance to degradation by soil nucleases and increased RNAi efficacy in Drosophila melanogaster cell cultures. In live insects, we found chemically modified long dsRNAs successfully resulted in mortality in both stink bug and corn rootworm. …”
Publicado 2022
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5515por Poppinga, Haiko, Çoban, Büşra, Meltzer, Hagar, Mayseless, Oded, Widmann, Annekathrin, Schuldiner, Oren, Fiala, André“…The mushroom body of the fruit fly Drosophila melanogaster is a well-established model circuit for examining the cellular mechanisms underlying neurite remodelling. …”
Publicado 2022
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5516por Tian, Aiguo, Morejon, Virginia, Kohoutek, Sarah, Huang, Yi‐Chun, Deng, Wu‐Min, Jiang, Jin“…Here, we show that infection of the Drosophila melanogaster intestine with pathogenic bacteria induces entry of enteroblasts (EBs), which are ISC progenies, into the mitotic cycle through upregulation of epidermal growth factor receptor (EGFR)‐Ras signaling. …”
Publicado 2022
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5517por Lobert, Viola H., Skardal, Maren L., Malerød, Lene, Simensen, Julia E., Algra, Hermine A., Andersen, Aram N., Fleischer, Thomas, Enserink, Hilde A., Liestøl, Knut, Heath, Joan K., Rusten, Tor Erik, Stenmark, Harald A.“…Silencing the sole PHLPP family phosphatase in Drosophila melanogaster, phlpp, resulted in defective spindle orientation in Drosophila neuroblasts. …”
Publicado 2022
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5518“…Survival in many animals requires the ability to associate certain cues with danger and others with safety. In a Drosophila melanogaster aversive olfactory conditioning paradigm, flies are exposed to two odours, one presented coincidentally with electrical shocks, and a second presented 45 s after shock cessation. …”
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5519“…We address this problem in the collective migration of the follicular epithelial cells in Drosophila melanogaster. In this epithelium, the cadherin Fat2 localizes to the trailing edge of each cell and promotes the formation of F-actin-rich protrusions at the leading edge of the cell behind. …”
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5520por De Nobrega, Aliza K., Noakes, Eric J., Storch, Natalie A., Mellers, Alana P., Lyons, Lisa C.“…We investigated sleep as a factor modulating alcohol toxicity using Drosophila melanogaster, a model for studies of sleep, alcohol, and aging. …”
Publicado 2022
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