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6021“…We demonstrate for the first time that adult Drosophila melanogaster glial cells undergo spontaneous functional recovery following crush injury. …”
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6022por Corgiat, Edwin B., List, Sara M., Rounds, J. Christopher, Corbett, Anita H., Moberg, Kenneth H.“…To gain insight into neurological functions of ZC3H14, we previously developed a Drosophila melanogaster model of ZC3H14 loss by deleting the fly ortholog, Nab2. …”
Publicado 2021
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6023por Ramond, Elodie, Jamet, Anne, Ding, Xiongqi, Euphrasie, Daniel, Bouvier, Clémence, Lallemant, Louison, He, Xiangyan, Arbibe, Laurence, Coureuil, Mathieu, Charbit, Alain“…Here, we establish a robust and easy-to-implement model of oral S. aureus infection using Drosophila melanogaster larvae that allowed us to follow the fate of S. aureus at the whole-organism level as well as the host immune responses. …”
Publicado 2021
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6024por Chowański, Szymon, Walkowiak-Nowicka, Karolina, Winkiel, Magdalena, Marciniak, Pawel, Urbański, Arkadiusz, Pacholska-Bogalska, Joanna“…It was also shown that ILPs in Drosophila melanogaster can directly and indirectly regulate AKH. …”
Publicado 2021
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6025por Wainman, Alan“…Studies have identified a conserved pathway of proteins required for centriole formation, and investigations using the embryo of the fruit fly Drosophila melanogaster have been crucial in elucidating their dynamics. …”
Publicado 2021
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6026por Mika, Kaan, Cruchet, Steeve, Chai, Phing Chian, Prieto-Godino, Lucia L., Auer, Thomas O., Pradervand, Sylvain, Benton, Richard“…We describe previously unknown receptor gene–dependent mechanisms that ensure singular expression of receptors encoded by a tandem gene array [Ionotropic receptor 75c (Ir75c), Ir75b, and Ir75a, organized 5′ to 3′] in Drosophila melanogaster. Transcription from upstream genes in the cluster runs through the coding region of downstream loci and inhibits their expression in cis, most likely via transcriptional interference. …”
Publicado 2021
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6027por Finet, Cédric, Kassner, Victoria A, Carvalho, Antonio B, Chung, Henry, Day, Jonathan P, Day, Stephanie, Delaney, Emily K, De Ré, Francine C, Dufour, Héloïse D, Dupim, Eduardo, Izumitani, Hiroyuki F, Gautério, Thaísa B, Justen, Jessa, Katoh, Toru, Kopp, Artyom, Koshikawa, Shigeyuki, Longdon, Ben, Loreto, Elgion L, Nunes, Maria D S, Raja, Komal K B, Rebeiz, Mark, Ritchie, Michael G, Saakyan, Gayane, Sneddon, Tanya, Teramoto, Machiko, Tyukmaeva, Venera, Vanderlinde, Thyago, Wey, Emily E, Werner, Thomas, Williams, Thomas M, Robe, Lizandra J, Toda, Masanori J, Marlétaz, Ferdinand“…The vinegar fly Drosophila melanogaster is a pivotal model for invertebrate development, genetics, physiology, neuroscience, and disease. …”
Publicado 2021
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6028Single-cell RNA-sequencing reveals pre-meiotic X-chromosome dosage compensation in Drosophila testis“…To address this, we analyzed testis single-cell RNA-sequencing (scRNA-seq) data from two Drosophila melanogaster strains. We found evidence that the X chromosome is equally transcriptionally active as autosomes in somatic and pre-meiotic cells, and less transcriptionally active than autosomes in meiotic and post-meiotic cells. …”
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6029“…Here, we take advantage of the model organism Drosophila melanogaster to investigate the role of AMPs and lysozymes in regulation of gut microbiota structure and diversity. …”
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6030“…In this study, a cellular repressor of E1A-stimulated gene (CREG)-like protein, which is highly conserved from Drosophila melanogaster to Homo sapiens, was further characterized in shrimp plasma. …”
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6031“…Protein components of the invertebrate occluding junction—known as the septate junction (SJ)—are required for morphogenetic developmental events during embryogenesis in Drosophila melanogaster. In order to determine whether SJ proteins are similarly required for morphogenesis during other developmental stages, we investigated the localization and requirement of four representative SJ proteins during oogenesis: Contactin, Macroglobulin complement-related, Neurexin IV, and Coracle. …”
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6032por Ibaraki, Kimihide, Nakatsuka, Mihoko, Ohsako, Takashi, Watanabe, Masahide, Miyazaki, Yu, Shirakami, Machi, Karr, Timothy L, Sanuki, Rikako, Tomaru, Masatoshi, Takano-Shimizu-Kouno, Toshiyuki“…Using male sterility genes identified in human, mouse, and fruit fly databases as a starting point, 103 Drosophila melanogaster genes were screened for their association with male sterility by tissue-specific RNAi knockdown and CRISPR/Cas9-mediated mutagenesis. …”
Publicado 2021
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6033“…Yet, the internal structure of the organism remains similar, i.e., the system scales to organism size. Drosophila melanogaster has been a powerful model system for exploring scaling mechanisms. …”
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6034“…The functions of mucin-type O-glycans have been studied in the fruit fly, Drosophila melanogaster. The basic structures of mucin-type O-glycans, including Tn antigen (GalNAcα1-Ser/Thr) and T antigen (Galβ1–3GalNAcα1-Ser/Thr), as well as the glycosyltransferases that synthesize them, are conserved between Drosophila and mammals. …”
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6035por de Medeiros Oliveira, Mauro, Bonadio, Igor, Lie de Melo, Alicia, Mendes Souza, Glaucia, Durham, Alan Mitchell“…We currently are the only application to offer pre-trained models for six different eukaryotic organisms: Arabidopsis thaliana, Drosophila melanogaster, Gallus gallus, Homo sapiens, Oryza sativa and Saccharomyces cerevisiae. …”
Publicado 2021
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6036por Ebanks, Brad, Wang, Ying, Katyal, Gunjan, Sargent, Chloe, Ingram, Thomas L., Bowman, Antonia, Moisoi, Nicoleta, Chakrabarti, Lisa“…We exercised w(1118) Drosophila melanogaster, investigating the effects of sex and group size at different stages of their lifetime, and recorded their lifespan. …”
Publicado 2021
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6037por Merinas-Amo, Tania, Lozano-Baena, María-Dolores, Obregón-Cano, Sara, Alonso-Moraga, Ángeles, de Haro-Bailón, Antonio“…In order to ascertain the heath properties in vitro and in vivo, toxicity activities were assayed in the Drosophila melanogaster and leukaemia cell models; genomic safety was also assessed in both models using genotoxicity, fragmentation and comet assay. …”
Publicado 2021
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6038por Bahuguna, Shivohum, Redhai, Siamak, Zhou, Jun, Wang, Tianyu, Port, Fillip, Boutros, Michael“…Here, we evaluate the CRISPR-Cas9 system in Drosophila melanogaster to assess its ability to induce stem cell-derived tumors in the intestine. …”
Publicado 2021
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6039“…Here, we report that in four different species – Caenorhabditis elegans, Caenorhabditis remanei, Drosophila melanogaster, and Danio rerio – octopamine and norepinephrine play an essential role in maintaining oocyte quiescence. …”
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6040“…Recent studies have just started to underscore the utility of the fruit fly Drosophila melanogaster as a model system to study virus-host interactions and pathogenicity. …”
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