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  1. 6261
    “…This subsequently led to the identification of the same enzyme in Drosophila melanogaster, Anopheles gambiae and Culex quinquefasciatus by an initial prediction of putative DHPAA synthase based on sequence homology and subsequent verification of DHPAA synthase identity through protein expression and activity assays. …”
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    From L-Dopa to Dihydroxyphenylacetaldehyde: A Toxic Biochemical Pathway Plays a Vital Physiological Function in Insects
  2. 6262
    “…Essential genes from representative model organisms, Mus musculus, Drosophila melanogaster, and Saccharomyces cerevisiae, are significantly enriched in universal orthologs within each lineage, and essential-gene-containing groups consistently exhibit greater sequence conservation than those without. …”
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    Correlating Traits of Gene Retention, Sequence Divergence, Duplicability and Essentiality in Vertebrates, Arthropods, and Fungi
  3. 6263
    “…Here, we survey population genetic variation at 105 orthologous X-linked protein coding regions in Drosophila melanogaster and its sister species D. simulans, two closely related species with distinct demographic histories. …”
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    Effective Population Size and the Efficacy of Selection on the X Chromosomes of Two Closely Related Drosophila Species
  4. 6264
    “…MiR-iab-4 and miR-iab-4as are known to regulate the expression of two Hox genes, Abd-A and Ubx, in Drosophila melanogaster. We have therefore studied the evolutionary changes of these two miR genes and their target sites of the Hox genes in Drosophila, other insect species, and Daphnia. …”
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    Evolutionary Changes of the Target Sites of Two MicroRNAs Encoded in the Hox Gene Cluster of Drosophila and Other Insect Species
  5. 6265
    por Zhang, Jing, Kuo, CC Jay, Chen, Liang
    Publicado 2011
    “…Here we perform a genomic study of RNA secondary structures around splice sites in humans (Homo sapiens), mice (Mus musculus), fruit flies (Drosophila melanogaster), and nematodes (Caenorhabditis elegans) to further investigate this phenomenon. …”
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    GC content around splice sites affects splicing through pre-mRNA secondary structures
  6. 6266
    “…BACKGROUND: Segmentation is a hallmark of the arthropods; most knowledge about the molecular basis of arthropod segmentation comes from work on the fly Drosophila melanogaster. In this species a hierarchic cascade of segmentation genes subdivides the blastoderm stepwise into single segment wide regions. …”
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    Expression of myriapod pair rule gene orthologs
  7. 6267
    “…To identify these proteins, we carried out genetic screens for mutations affecting Drosophila melanogaster sperm storage, a process mediated by Drosophila Pkd2. …”
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    Regulation of flagellar motility by the conserved flagellar protein CG34110/Ccdc135/FAP50
  8. 6268
    “…In the developing wing primordium of Drosophila melanogaster, signaling by the secreted protein Hedgehog (Hh) is required for compartment boundary maintenance. …”
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    Cell-Sorting at the A/P Boundary in the Drosophila Wing Primordium: A Computational Model to Consolidate Observed Non-Local Effects of Hh Signaling
  9. 6269
    “…METHODOLOGY/RESULTS: We used network analyses of proteomic and transcriptomic data to evaluate pathways in Drosophila melanogaster that are affected by acute METH toxicity. …”
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    Systems-Scale Analysis Reveals Pathways Involved in Cellular Response to Methamphetamine
  10. 6270
    por de la Chaux, Nicole, Wagner, Andreas
    Publicado 2009
    “…BACKGROUND: Roo is the most abundant retrotransposon in the fruit fly Drosophila melanogaster. Its evolutionary origins and dynamics are thus of special interest for understanding the evolutionary history of Drosophila genome organization. …”
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    Evolutionary dynamics of the LTR retrotransposons roo and rooA inferred from twelve complete Drosophila genomes
  11. 6271
    “…This is especially the case for the Sp gene buttonhead (btd) which plays a key role in head development in Drosophila melanogaster, and has been proposed to have originated by a recent gene duplication. …”
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    A clustered set of three Sp-family genes is ancestral in the Metazoa: evidence from sequence analysis, protein domain structure, developmental expression patterns and chromosomal location
  12. 6272
    “…A comparative genomic analysis of these genes along with those present in Drosophila melanogaster, Tribolium castaneum and several other insect species led to a uniform classification and nomenclature of these genes. …”
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    Comparative Genomic Analysis of Chitinase and Chitinase-Like Genes in the African Malaria Mosquito (Anopheles gambiae)
  13. 6273
    “…In various species including Drosophila melanogaster female sperm storage is a necessary step in the reproductive process. …”
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    Drosophila Sperm Swim Backwards in the Female Reproductive Tract and Are Activated via TRPP2 Ion Channels
  14. 6274
    por Magico, Adam C., Bell, John B.
    Publicado 2011
    “…Drosophila melanogaster wing development has been shown to rely on the activity of a complex of two proteins, Scalloped (Sd) and Vestigial (Vg). …”
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    Identification of a Classical Bipartite Nuclear Localization Signal in the Drosophila TEA/ATTS Protein Scalloped
  15. 6275
    “…By comparing expression profiles with Drosophila melanogaster we also assessed which genes are well conserved within the Diptera versus those that are more recently evolved. …”
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    A comprehensive gene expression atlas of sex- and tissue-specificity in the malaria vector, Anopheles gambiae
  16. 6276
    “…Drosophila melanogaster is a model organism instrumental for numerous biological studies. …”
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    Analysis of Micro- and Nano-Structures of the Corneal Surface of Drosophila and Its Mutants by Atomic Force Microscopy and Optical Diffraction
  17. 6277
    “…Characteristics of TRs in different genomic regions and among different strands are compared in details for D. pulex and the two model insects Apis mellifera and Drosophila melanogaster. RESULTS: Profound differences in TR characteristics were found among all 12 genomes compared in this study. …”
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    Genome-wide analysis of tandem repeats in Daphnia pulex - a comparative approach
  18. 6278
    “…Previous studies with Drosophila melanogaster showed that, as in yeast, loss of both DmBLM and MUS81 or MUS312 (the ortholog of SLX4) is lethal. …”
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    Three Structure-Selective Endonucleases Are Essential in the Absence of BLM Helicase in Drosophila
  19. 6279
    “…Genome data of three vertebrate species (Homo sapiens, Mus musculus, and Danio rerio), Caenorhabditis elegans, and two Drosophila species (Drosophila melanogaster and D. pseudoobscura) were used. Duplication events were divided into six age-groups according to the synonymous distance (dS) up to 0.6. …”
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    Evolutionary Patterns of Recently Emerged Animal Duplogs
  20. 6280
    “…The injection or feeding of V. spinosum to Drosophila melanogaster and Caenorhabditis elegans, respectively, was shown to result in increased mortality rates relative to controls, a phenomenon exaggerated in C. elegans mutants hypersensitive to pathogen infection. …”
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    Genomic and Experimental Evidence Suggests that Verrucomicrobium spinosum Interacts with Eukaryotes
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