“…RESULTS: We use heat shock as a stressor to test this prediction in Drosophila melanogaster. We find that increased exposure to heat shock conditions is associated with a non-linear increase in meiotic recombination frequency. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We analysed Chd64 in two unrelated insect species, Drosophila melanogaster (DmChd64) and Tribolium castaneum (TcChd64). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We analyzed the public RNA-seq datasets generated from RNAi experiments on Drosophila melanogaster S2-DRSC cells to deplete RNA-binding proteins (GSE18508). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here we present the crystal structures of the eIF4E-binding regions of the Drosophila melanogaster (Dm) and Caenorhabditis elegans (Ce) Mxt proteins in complex with eIF4E in the cap-bound and cap-free states. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We found that between 5 and 10% of all L. stagnalis maternal transcripts (~300-400 genes) are also present in the equivalent arthropod (Drosophila melanogaster), nematode (Caenorhabditis elegans), urochordate (Ciona intestinalis) and chordate (Homo sapiens, Mus musculus, Danio rerio) datasets. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Downregulation of Rpd3, a homologue of mammalian Histone Deacetylase 1 (HDAC1), extends lifespan in Drosophila melanogaster. Once revealed that long-lived fruit flies exhibit limited cardiac decline, we investigated whether Rpd3 downregulation would improve stress resistance and/or lifespan when targeted in the heart. …”
Enlace del recurso
Enlace del recurso

“…It has been shown that TEs are a considerable source of adaptive changes in the genome of Drosophila melanogaster. Specifically, footprints of selection at the DNA level, the presence of population differentiation patterns across environmental gradients, and detailed mechanistic and fitness analyses of a few candidate adaptive TEs pointed to the role of TEs in environmental adaptation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In most animals that have X and Y sex chromosomes, chromosome-wide mechanisms are used to balance X-linked gene expression in males and females. In the fly Drosophila melanogaster, the dosage compensation mechanism also generally extends to X-linked transgenes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We used 197 Drosophila melanogaster Genetic Reference Panel (DGRP) lines to perform a genome-wide association analysis for virgin female lifespan, using ~2M common single nucleotide polymorphisms (SNPs). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This study was conducted to determine if acacetin extracted from the whole Agastache rugosa plant had anti-BACE-1 and behavioral activities in Drosophila melanogaster AD models and to determine acacetin’s mechanism of action. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Sister chromatid cohesion factors, including the Nipped-B ortholog of NIPBL, are also critical for gene expression and development in Drosophila melanogaster. Here we describe how a modest reduction in Nipped-B activity alters growth and neurological function in Drosophila. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…However, choosing a spouse from numerous attractive partners of the opposite sex needs deliberation. In Drosophila melanogaster, both younger virgin females and older ones are equally liked options to males; nevertheless, when given options, males prefer younger females to older ones. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…North American populations of Drosophila melanogaster derive from both European and African source populations, but despite their importance for genetic research, patterns of ancestry along their genomes are largely undocumented. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The main developmental mechanisms involved have been elucidated in Drosophila melanogaster, but recent studies have shown that other insect orders often diverge in RNA localisation patterns. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Recently, dRYamides-1 and -2 have been identified as ligands of the neuropeptide Y-like receptor CG5811 in Drosophila melanogaster. It has also been reported in brief that injection of dRYamide-1suppresses the early feeding behavior called proboscis extension reflex (PER) in the blowfly Phormia regina. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, we draw on examples from studies in Caenorhabditis elegans, Drosophila melanogaster, and vertebrates to discuss how the terms spatial selector, temporal selector, tissue/cell type selector, terminal selector and combinatorial code may be usefully applied to categorize the activities of TF's at critical steps of nervous system construction. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We cloned Ca-α1T, the only Ca(v)3 channel gene in Drosophila melanogaster, expressed it in Xenopus oocytes and HEK-293 cells, and confirmed it passes typical T-type currents. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The function of rhodopsin-like GPCR was further confirmed using transgenic lines of Drosophila melanogaster, in which the tolerance to permethrin and the expression of Drosophila resistance P450 genes were both increased. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Most quantitative trait loci (QTL) mapping studies of genitalia divergence have focused on Drosophila melanogaster and its three most closely related species, D. simulans, D. mauritiana, and D. sechellia, and have suggested that the genetic basis of genitalia evolution involves many loci. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…A comparable circuitry detected in a different nervous system in a remote species—the olfactory circuitry of the fruit fly Drosophila melanogaster—provides an opportunity to explore circuit functions using genetic manipulations, which, along with high-resolution microscopic techniques and lipid membrane interaction studies, will be able to verify the structure–function details of the presented mechanism of perception.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso