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6521por Torres-Oliva, Montserrat, Almeida, Francisca C., Sánchez-Gracia, Alejandro, Rozas, Julio“…The members of the CheB family are specialized in gustatory-mediated detection of long-chain hydrocarbon pheromones in Drosophila melanogaster and play a central role in triggering and modulating mating behavior in this species. …”
Publicado 2016
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6522“…Rpvgsc1 showed 64.1% amino acid identity to DI–DII of Drosophila melanogaster VGSC and Rpvgsc2 showed 64.0% amino acid identity to DIII–DIV of D. melanogaster VGSC. …”
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6523por Schivo, Stefano, Scholma, Jetse, van der Vet, Paul E., Karperien, Marcel, Post, Janine N., van de Pol, Jaco, Langerak, Rom“…We show this by presenting ANIMO models for two case studies: Drosophila melanogaster circadian clock, and signal transduction events downstream of TNF α and EGF in HT-29 human colon carcinoma cells. …”
Publicado 2016
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6524por Janssen, Aniek, Breuer, Gregory A., Brinkman, Eva K., van der Meulen, Annelot I., Borden, Sean V., van Steensel, Bas, Bindra, Ranjit S., LaRocque, Jeannine R., Karpen, Gary H.“…Here, we developed an in vivo single DSB system for both heterochromatic and euchromatic loci in Drosophila melanogaster. Live imaging of single DSBs in larval imaginal discs recapitulates the spatio–temporal dynamics observed for irradiation (IR)-induced breaks in cell culture. …”
Publicado 2016
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6525por Maisuria, Vimal B., Los Santos, Yossef Lopez-de, Tufenkji, Nathalie, Déziel, Eric“…In this study, we demonstrate an anti-virulence activity of a cranberry extract rich in proanthocyanidins (cerPAC) against P. aeruginosa in the model host Drosophila melanogaster and show this is mediated by QS interference. cerPAC reduced the production of QS-regulated virulence determinants and protected D. melanogaster from fatal infection by P. aeruginosa PA14. …”
Publicado 2016
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6526por Merenciano, Miriam, Ullastres, Anna, de Cara, M. A. R., Barrón, Maite G., González, Josefa“…Recent alternative promoter usage analyses in Drosophila melanogaster revealed that transposable elements significantly contribute to promote diversity. …”
Publicado 2016
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6527por Christensen, Steen, Pérez Dulzaides, Ricardo, Hedrick, Victoria E., Momtaz, A. J. M. Zehadee, Nakayasu, Ernesto S., Paul, Lake N., Serbus, Laura R.“…To investigate transmission-related processes in response to Wolbachia infection, ovarian proteomes were analyzed from Wolbachia-infected Drosophila melanogaster and D. simulans. Endogenous and variant host-strain combinations were investigated. …”
Publicado 2016
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6528por Elyashiv, Eyal, Sattath, Shmuel, Hu, Tina T., Strutsovsky, Alon, McVicker, Graham, Andolfatto, Peter, Coop, Graham, Sella, Guy“…To illustrate the utility of our approach, we apply it to genome-wide resequencing data from 125 lines in Drosophila melanogaster and reliably predict diversity levels at the 1Mb scale. …”
Publicado 2016
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6529por Furukubo-Tokunaga, Katsuo, Kurita, Kazuki, Honjo, Ken, Pandey, Himani, Ando, Tetsuya, Takayama, Kojiro, Arai, Yuko, Mochizuki, Hiroaki, Ando, Mai, Kamiya, Atsushi, Sawa, Akira“…To explore its functions in a genetically tractable system, we expressed the human DISC1 in fruit flies (Drosophila melanogaster). As in mammalian neurons, DISC1 is localized to diverse subcellular domains of developing fly neurons including the nuclei, axons and dendrites. …”
Publicado 2016
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6530“…It occurs universally as heterotrimeric complexes containing catalytic α subunits and regulatory β and γ subunits. Although Drosophila melanogaster contains single genes encoding each subunit, in mammals, each subunit exists as multiple isoforms encoded by distinct genes, giving rise to up to 12 heterotrimeric combinations. …”
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6531por Rangel, Lorena I., Henkels, Marcella D., Shaffer, Brenda T., Walker, Francesca L., Davis, Edward W., Stockwell, Virginia O., Bruck, Denny, Taylor, Barbara J., Loper, Joyce E.“…Ten strains representing four lineages of the Pseudomonas fluorescens group (P. chlororaphis, P. corrugata, P. koreensis, and P. fluorescens subgroups) were evaluated for toxicity to the tobacco hornworm Manduca sexta and the common fruit fly Drosophila melanogaster. The three strains within the P. chlororaphis subgroup exhibited both oral and injectable toxicity to the lepidopteran M. sexta. …”
Publicado 2016
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6532por Rezával, Carolina, Pattnaik, Siddharth, Pavlou, Hania J., Nojima, Tetsuya, Brüggemeier, Birgit, D’Souza, Luis A.D., Dweck, Hany K.M., Goodwin, Stephen F.“…Courtship in Drosophila melanogaster offers a powerful experimental paradigm for the study of innate sexually dimorphic behaviors [1, 2]. …”
Publicado 2016
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6533por Redhai, Siamak, Hellberg, Josephine E. E. U., Wainwright, Mark, Perera, Sumeth W., Castellanos, Felix, Kroeger, Benjamin, Gandy, Carina, Leiblich, Aaron, Corrigan, Laura, Hilton, Thomas, Patel, Benjamin, Fan, Shih-Jung, Hamdy, Freddie, Goberdhan, Deborah C. I., Wilson, Clive“…Here we demonstrate that each prostate-like secondary cell (SC) in the paired adult Drosophila melanogaster male accessory glands contains approximately ten large DCGs, which are loaded with the Bone Morphogenetic Protein (BMP) ligand Decapentaplegic (Dpp). …”
Publicado 2016
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6534“…Here we tested how the transcriptome responds to mtDNA and nDNA variation, along with mitonuclear interactions (mtDNA × nDNA) in Drosophila melanogaster. We used two mtDNA haplotypes that differ in a substantial number of single nucleotide polymorphisms, with >100 amino acid differences. …”
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6535“…Where insufficient information is available in mosquitoes, we describe analogous processes in other organisms, such as Drosophila melanogaster, as a basis for comparison, and we suggest future areas of research that will illuminate how sperm successfully traverse the female reproductive tract. …”
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6536por Jungreis, Irwin, Chan, Clara S., Waterhouse, Robert M., Fields, Gabriel, Lin, Michael F., Kellis, Manolis“…Using improved comparative genomics methods for detecting readthrough, we identify evolutionary signatures of conserved, functional readthrough of 353 stop codons in the malaria vector, Anopheles gambiae, and of 51 additional Drosophila melanogaster stop codons, including several cases of double and triple readthrough and of readthrough of two adjacent stop codons. …”
Publicado 2016
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6537por Kaas, Garrett A., Kasuya, Junko, Lansdon, Patrick, Ueda, Atsushi, Iyengar, Atulya, Wu, Chun-Fang, Kitamoto, Toshihiro“…Shudderer (Shu) is an X-linked dominant mutation in Drosophila melanogaster identified more than 40 years ago. …”
Publicado 2016
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6538por Egan, Brian, Yuan, Chih-Chi, Craske, Madeleine Lisa, Labhart, Paul, Guler, Gulfem D., Arnott, David, Maile, Tobias M., Busby, Jennifer, Henry, Chisato, Kelly, Theresa K., Tindell, Charles A., Jhunjhunwala, Suchit, Zhao, Feng, Hatton, Charlie, Bryant, Barbara M., Classon, Marie, Trojer, Patrick“…We overcome this challenge by employing an alternative normalization approach that is based on the addition of Drosophila melanogaster chromatin and a D. melanogaster-specific antibody into standard ChIP reactions. …”
Publicado 2016
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6539por Tan, Shengjun, Cardoso-Moreira, Margarida, Shi, Wenwen, Zhang, Dan, Huang, Jiawei, Mao, Yanan, Jia, Hangxing, Zhang, Yaqiong, Chen, Chunyan, Shao, Yi, Leng, Liang, Liu, Zhonghua, Huang, Xun, Long, Manyuan, Zhang, Yong E.“…Here, we examined young retrocopies from various animals that still retain the sequence features indicative of the underlying retroposition mechanism. In Drosophila melanogaster, we identified and de novo assembled 15 polymorphic retrocopies and found that all retroposed loci are chimeras of internal retrocopies flanked by discontinuous LTR retrotransposons. …”
Publicado 2016
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6540por Kaiser, Tobias S., Poehn, Birgit, Szkiba, David, Preussner, Marco, Sedlazeck, Fritz J., Zrim, Alexander, Neumann, Tobias, Nguyen, Lam-Tung, Betancourt, Andrea J., Hummel, Thomas, Vogel, Heiko, Dorner, Silke, Heyd, Florian, von Haeseler, Arndt, Tessmar-Raible, Kristin“…As equivalent variants were shown to alter CaMKII activity in Drosophila melanogaster, and C. marinus (Cma)-CaMKII.1 increases the transcriptional activity of the dimer of the circadian proteins Cma-CLOCK and Cma-CYCLE, we suggest that modulation of alternative splicing is a mechanism for natural adaptation in circadian timing. …”
Publicado 2016
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