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  1. 6681
    “…In Drosophila melanogaster, aversive (electric shock) stimuli have been shown to activate subpopulations of dopaminergic neurons with terminals in the mushroom bodies (MBs) of the brain. …”
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    Dopamine release in mushroom bodies of the honey bee (Apis mellifera L.) in response to aversive stimulation
  2. 6682
    “…To evaluate potential biological effects of elevated Condensin II levels, we overexpressed the Condensin II subunit, dCAP-D3 in Drosophila melanogaster larval tissues and examined the effects on the mitotic- and interphase-specific functions of Condensin II. …”
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    Comparing and Contrasting the Effects of Drosophila Condensin II Subunit dCAP-D3 Overexpression and Depletion in Vivo
  3. 6683
    “…Targeted depletion of OXA1L in human cells or Drosophila melanogaster caused defects in the assembly of complexes I, IV and V, consistent with patient data. …”
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    OXA1L mutations cause mitochondrial encephalopathy and a combined oxidative phosphorylation defect
  4. 6684
    “…Using a recombinant subunit platform consisting of antigens produced in Drosophila melanogaster S2 cells, we have previously shown seroconversion and protection against viremia in an immunocompetent mouse model. …”
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    A Recombinant Subunit Based Zika Virus Vaccine Is Efficacious in Non-human Primates
  5. 6685
    “…Chemosensory proteins have been identified and analyzed in many insect species, such as Drosophila melanogaster, Bactrocera dorsalis and Calliphora stygia. …”
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    Transcriptomics reveal the molecular underpinnings of chemosensory proteins in Chlorops oryzae
  6. 6686
    “…Here, we have analyzed the genomes of a set of Drosophila melanogaster lines that have been maintained under direct selection for postponed reproduction and indirect selection for longevity, relative to unselected control lines, for over 35 years. …”
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    Evolution of longevity improves immunity in Drosophila
  7. 6687
    por Roy, Amit, Palli, Subba Reddy
    Publicado 2018
    “…Antagonistic activities of histone acetyltransferases (HATs) and histone deacetylases (HDACs) mediate transcriptional reprogramming during insect development as shown in Drosophila melanogaster and other insects. Juvenile hormones (JH) play vital roles in the regulation of growth, development, metamorphosis, reproduction and other physiological processes. …”
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    Epigenetic modifications acetylation and deacetylation play important roles in juvenile hormone action
  8. 6688
    por Tucker, Richard P.
    Publicado 2018
    “…For example, in the chicken embryo neurons forming the tectofugal pathway express teneurin-1, whereas neurons forming the thalamofugal pathway express teneurin-2. In Drosophila melanogaster, Caenorhabditis elegans, zebrafish and mice, misexpression or knocking out teneurin expression leads to abnormal connections in the neural networks that normally express the relevant teneurin. …”
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    Teneurins: Domain Architecture, Evolutionary Origins, and Patterns of Expression
  9. 6689
    “…Here, we combinatorially dissect the natural microbiome of Drosophila melanogaster and reveal that interactions between bacteria shape host fitness through life history tradeoffs. …”
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    Microbiome interactions shape host fitness
  10. 6690
    “…The abundant population and comparative genomic resources of Drosophila melanogaster and its close relatives offer us a unique opportunity to fill this gap. …”
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    Recurrent Innovation at Genes Required for Telomere Integrity in Drosophila
  11. 6691
    “…We sought to determine the contributions of most Drosophila melanogaster larval ORNs to navigational behavior. …”
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    Behavior Responses to Chemical and Optogenetic Stimuli in Drosophila Larvae
  12. 6692
    “…We showed previously that the Drosophila melanogaster KDM4A (dKDM4A) histone demethylase is required for heterochromatic DSB mobility. …”
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    Timely double-strand break repair and pathway choice in pericentromeric heterochromatin depend on the histone demethylase dKDM4A
  13. 6693
    “…Intracellular JH receptors have recently been established as basic helix-loop-helix transcription factor (bHLH)/PAS proteins in Drosophila melanogaster known as germ cell–expressed (Gce) and its duplicate paralog, methoprene-tolerant (Met). …”
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    Exquisite ligand stereoselectivity of a Drosophila juvenile hormone receptor contrasts with its broad agonist repertoire
  14. 6694
    “…Here, we manipulate the polyandry levels in groups of Drosophila melanogaster by deletion of the female sex peptide receptor. …”
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    Sex peptide receptor-regulated polyandry modulates the balance of pre- and post-copulatory sexual selection in Drosophila
  15. 6695
    por Deal, Samantha L., Yamamoto, Shinya
    Publicado 2019
    “…Over the past few decades, the fruit fly, Drosophila melanogaster, has become an integral tool to understand the molecular, cellular and genetic mechanisms underlying neurodegeneration. …”
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    Unraveling Novel Mechanisms of Neurodegeneration Through a Large-Scale Forward Genetic Screen in Drosophila
  16. 6696
    “…Although many strains of Spiroplasma, including the male-killing symbiont (sMel) of Drosophila melanogaster, protect against parasitic wasps, only the strain (sNeo) that infects the mycophagous fly Drosophila neotestacea appears to protect against parasitic nematodes. …”
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    Toxin and Genome Evolution in a Drosophila Defensive Symbiosis
  17. 6697
    “…In this work, we analyzed the population frequencies of 1,615 Transposable Element (TE) insertions annotated in the reference genome of Drosophila melanogaster, in 91 samples from 60 worldwide natural populations. …”
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    Stress response, behavior, and development are shaped by transposable element-induced mutations in Drosophila
  18. 6698
    “…The Hippo pathway is a conserved signaling pathway originally defined in Drosophila melanogaster two decades ago. Deregulation of the Hippo pathway leads to significant overgrowth in phenotypes and ultimately initiation of tumorigenesis in various tissues. …”
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    WW Domain-Containing Proteins YAP and TAZ in the Hippo Pathway as Key Regulators in Stemness Maintenance, Tissue Homeostasis, and Tumorigenesis
  19. 6699
    “…Bombyx mori is a lepidopteran insect, whose body size is larger than the model insect Drosophila melanogaster, which enabled us to more easily examine gene expression at the tissue level. …”
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    Comparative analysis of seven types of superoxide dismutases for their ability to respond to oxidative stress in Bombyx mori
  20. 6700
    “…Thermal performance curves (TPCs) compute the effects of temperature on the performance of ectotherms and are frequently used to predict the effect of environmental conditions and currently, climate change, on organismal vulnerability and sensitivity. Using Drosophila melanogaster as an animal model, we examined how different thermal environments affected the shape of the performance curve and their parameters. …”
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    Transgenerational and within‐generation plasticity shape thermal performance curves
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