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  1. 7481
    “…We combine a chemically-synthesized, voltage-sensitive fluorophore with a genetically encoded, self-labeling enzyme to enable voltage imaging in Drosophila melanogaster. Previously, we showed that a rhodamine voltage reporter (RhoVR) combined with the HaloTag self-labeling enzyme could be used to monitor membrane potential changes from mammalian neurons in culture and brain slice. …”
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    Voltage Imaging in Drosophila Using a Hybrid Chemical-Genetic Rhodamine Voltage Reporter
  2. 7482
    “…Using phenotypic assays and available data from transcriptomics, PacBio genomes, and sequence variation from global populations, we explore the selective forces acting on glue genes within the cosmopolitan Drosophila melanogaster species and its five closely related species, D. simulans, D. sechellia, D. mauritiana, D. yakuba, and D. teissieri. …”
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    Glue Genes Are Subjected to Diverse Selective Forces during Drosophila Development
  3. 7483
    “…Remarkably, the fruit fly Drosophila melanogaster, expresses a GSTE14 with notable steroid isomerase activity, even though Ser14 has evolved as the active-site residue corresponding to Tyr9 in the mammalian alpha class.…”
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    Glutathione Transferases as Efficient Ketosteroid Isomerases
  4. 7484
    por Linheiro, Raquel, Archer, John
    Publicado 2021
    “…For simulated data, ten million read pairs were generated from cDNA libraries representing four species, Drosophila melanogaster, Panthera pardus, Rattus norvegicus and Serinus canaria. …”
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    CStone: A de novo transcriptome assembler for short-read data that identifies non-chimeric contigs based on underlying graph structure
  5. 7485
    “…Moreover, two influential studies reported that the cGAS-like receptors (cGLRs) of fly Drosophila melanogaster sense RNA and control 3′-2′-cGAMP signaling. …”
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    Roles of Emerging RNA-Binding Activity of cGAS in Innate Antiviral Response
  6. 7486
    “…To explore this possibility, here we develop a transgenic line of Drosophila melanogaster expressing Cas9 from the Y chromosome. …”
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    Exploiting a Y chromosome-linked Cas9 for sex selection and gene drive
  7. 7487
    “…Next to H. sapiens, SignaLink3 is the only current signaling network resource to provide regulatory information for the model species Caenorhabditis elegans and Danio rerio, and the largest resource for Drosophila melanogaster. Compared to previous versions, we have integrated gene expression data as well as subcellular localization of the interactors, therefore uniquely allowing tissue-, or compartment-specific pathway interaction analysis to create more accurate models. …”
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    SignaLink3: a multi-layered resource to uncover tissue-specific signaling networks
  8. 7488
    “…In this study, two Sprs (CG12116 and Sptr) from Drosophila melanogaster were found to be downregulated in transgenic flies overexpressing white spot syndrome virus (WSSV) immediate-early protein WSV056. …”
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    WSV056 Inhibits Shrimp Nitric Oxide Synthase Activity by Downregulating Litopenaeus vannamei Sepiapterin Reductase to Promote White Spot Syndrome Virus Replication
  9. 7489
    “…However, little is known about selective regulation of individual rDNA units. In Drosophila melanogaster, some rDNA repeats contain insertions of the R2 retrotransposon, which is capable to be transcribed only as part of pre-rRNA molecules. rDNA units with R2 insertions are usually inactivated, although R2 expression may be beneficial in cells with decreased rDNA copy number. …”
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    Impaired function of rDNA transcription initiation machinery leads to derepression of ribosomal genes with insertions of R2 retrotransposon
  10. 7490
    “…Testing on MS2-MCP fluorescent data collected from early Drosophila melanogaster embryos indicates that the method provides accurate inference of kinetic parameters within a computationally feasible timeframe. …”
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    Scalable inference of transcriptional kinetic parameters from MS2 time series data
  11. 7491
    “…In the worm Caenorhabditis elegans, mutated SDH creates developmental abnormalities, metabolic rewiring, an energy deficit and oxygen hypersensitivity (the latter is also found in Drosophila melanogaster). In the zebrafish Danio rerio, sdhb mutants display a shorter lifespan with defective energy metabolism. …”
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    Model systems in SDHx-related pheochromocytoma/paraganglioma
  12. 7492
    “…Disruption of the MRM2 Drosophila melanogaster orthologue leads to mitochondria-related developmental arrest. …”
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    A late-stage assembly checkpoint of the human mitochondrial ribosome large subunit
  13. 7493
    “…It is a potent pathogen in a septic injury model of Drosophila melanogaster since a few bacteria directly injected in the body cavity kill the insect within a day. …”
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    The fliR gene contributes to the virulence of S. marcescens in a Drosophila intestinal infection model
  14. 7494
    “…The latter indicates Z. renardii interplay with relevant insect targets, such as Philaenus spumarius, Neophilaenus campestris, Bactrocera oleae, Kermes vermilio, Nidularia pulvinata, Harmonia axyridis, Apis mellifera, Aleurocanthus spiniferus, Aleurothrixus floccosus, Macrohomotoma gladiata, Drosophila suzukii, Drosophila melanogaster, Megaselia scalaris, Pseudococcidae, Miridae, and Issidae. …”
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    Zelus renardii Roaming in Southern Italy
  15. 7495
    “…Aging is a risk factor for neurodegenerative disease, but precise mechanisms that influence this relationship are still under investigation. Work in Drosophila melanogaster identified the microRNA miR‐34 as a modifier of aging and neurodegeneration in the brain. …”
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    Loss of miR‐34 in Drosophila dysregulates protein translation and protein turnover in the aging brain
  16. 7496
    “…Custom motifs designed from annotated OBPs of Aedes aegypti, Drosophila melanogaster, and Anopheles gambiae were used for the identification of putative OBPs from protein sequences of the An. stephensi Indian strain. …”
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    Odorant Binding Proteins (OBPs) and Odorant Receptors (ORs) of Anopheles stephensi: Identification and comparative insights
  17. 7497
    “…The Aedes aegypti G protein-coupled receptors AAEL024199 (AeCNMaR-1a) and AAEL018316 (AeCNMaR-1b) were identified as orthologs of the Drosophila melanogaster CNMa receptor (DmCNMaR). The receptor was duplicated early in the evolution of insects, and subsequently in Culicidae, into what we refer to as CNMaR-1a and CNMaR-1b. …”
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    The Peptide Hormone CNMa Influences Egg Production in the Mosquito Aedes aegypti
  18. 7498
    “…Like other well-studied arthropods such as Drosophila melanogaster and Anopheles gambiae, D. magna is a small, widespread, and abundant species that is therefore expected to display a large long-term population size and high rates of adaptive protein evolution. …”
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    Population-Genomic Analysis Identifies a Low Rate of Global Adaptive Fixation in the Proteins of the Cyclical Parthenogen Daphnia magna
  19. 7499
    “…The number and location of crossovers across genomes are highly regulated during meiosis, yet the key components controlling them are fast evolving, hindering our understanding of the mechanistic causes and evolutionary consequences of changes in crossover rates. Drosophila melanogaster has been a model species to study meiosis for more than a century, with an available high-resolution crossover map that is, nonetheless, missing for closely related species, thus preventing evolutionary context. …”
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    Meiotic, genomic and evolutionary properties of crossover distribution in Drosophila yakuba
  20. 7500
    “…Compared to non-jumping dipteran larvae, such as Drosophila melanogaster, the overall arrangement is highly similar, but a few muscle fibres show characteristic re-arrangements in orientation and strength that are consistent with a role in bending and jumping. …”
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    Rearrangements in the musculature correlate with jumping behaviour in legless Mediterranean fruit fly larvae Ceratitis capitata (Tephritidae)
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