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Mostrando 7,821 - 7,840 Resultados de 8,019 Para Buscar '"Drosophila melanogaster"', tiempo de consulta: 2.99s Limitar resultados
  1. 7821
    “…Myosuppressin binds to G protein-coupled receptor (GPCR) proteins. Two Drosophila melanogaster myosuppressin receptors (DrmMS-Rs) exist; however, no mechanism underlying MS-R activation is reported. …”
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    Cardiac Contractility Structure-Activity Relationship and Ligand-Receptor Interactions; the Discovery Of Unique and Novel Molecular Switches in Myosuppressin Signaling
  2. 7822
    “…Although studies on different animals have revealed commonalities in gut formation, the model systems Caenorhabditis elegans and Drosophila melanogaster, which belong to the invertebrate group Ecdysozoa, exhibit remarkable deviations in how their intestines develop. …”
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    The study of Priapulus caudatus reveals conserved molecular patterning underlying different gut morphogenesis in the Ecdysozoa
  3. 7823
    “…Most of our current knowledge about the developmental and molecular mechanisms involved in eye formation in arthropods comes from research in the model system Drosophila melanogaster. Here, a core set of retinal determination genes, namely, sine-oculis (so), eyes absent (eya), dachshund (dac), and the two pax6 orthologues eyeless (ey) and twin of eyeless (toy) govern early retinal development. …”
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    Molecular characterization and embryonic origin of the eyes in the common house spider Parasteatoda tepidariorum
  4. 7824
    “…RESULTS: Here we describe Drosophila melanogaster tRFs, which appear to have a number of structural and functional features similar to those of miRNAs but are less abundant. …”
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    Age-driven modulation of tRNA-derived fragments in Drosophila and their potential targets
  5. 7825
    “…To date, studies of insects have been best represented by the model system Drosophila melanogaster. Given the enormous diversity represented by insect taxa, comparative studies within this clade will provide a wealth of information about the evolutionary potential and trajectories of alternative developmental strategies. …”
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    Dermestes maculatus: an intermediate-germ beetle model system for evo-devo
  6. 7826
    “…Moreover, the Drosophila melanogaster ortholog Lgd was shown to be involved in the endosomal trafficking of the Notch receptor and other transmembrane receptors and physically interacts with the ESCRT-III component Shrub/CHMP4. …”
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    The Mammalian Orthologs of Drosophila Lgd, CC2D1A and CC2D1B, Function in the Endocytic Pathway, but Their Individual Loss of Function Does Not Affect Notch Signalling
  7. 7827
    “…Conservative molecular clock estimates based on synonymous substitution rates for species of Anopheles mosquitoes and the fruit fly, Drosophila melanogaster, suggest these events occurred within the last 50 MYA. …”
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    Paralog analyses reveal gene duplication events and genes under positive selection in Ixodes scapularis and other ixodid ticks
  8. 7828
    “…BACKGROUND: The contribution of programmed cell death (PCD) to muscle wasting disorders remains a matter of debate. Drosophila melanogaster metamorphosis offers the opportunity to study muscle cell death in the context of development. …”
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    Live imaging of muscle histolysis in Drosophila metamorphosis
  9. 7829
    “…One of the most thoroughly characterized GRNs is the dorsoventral (DV) patterning system of the Drosophila melanogaster embryo. We have developed the wasp Nasonia as a comparative DV patterning model because it has shown the convergent evolution of a mode of early embryonic patterning very similar to that of the fly, and it is of interest to know whether the similarity at the gross level also extends to the molecular level. …”
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    Global analysis of dorsoventral patterning in the wasp Nasonia reveals extensive incorporation of novelty in a regulatory network
  10. 7830
    “…Genes of subfamilies ABCA, ABCC and ABCH were found to be expanded in P. xylostella compared with those in Bombyx mori, Manduca sexta, Heliconius melpomene, Danaus plexippus, Drosophila melanogaster, Tetranychus urticae and Homo sapiens. …”
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    Characterization and expression profiling of ATP-binding cassette transporter genes in the diamondback moth, Plutella xylostella (L.)
  11. 7831
    por Bahk, Suhyoung, Jones, Walton D.
    Publicado 2016
    “…In this study, we explore the relationship between Orco and CaM in vivo in the olfactory neurons of Drosophila melanogaster. RESULTS: We first found OSN-specific knock-down of CaM at the onset of OSN development disrupts the spontaneous firing of OSNs and reduces Orco trafficking to the ciliated dendrites of OSNs without affecting their morphology. …”
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    Insect odorant receptor trafficking requires calmodulin
  12. 7832
    “…We confront the neutral and panmictic model to “ideal” empirical data (in silico RAD-sequencing) using full genomes from natural populations of the fruit fly Drosophila melanogaster and the fungus Shizophyllum commune, harbouring respectively moderate and high genetic diversity. …”
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    How and how much does RAD-seq bias genetic diversity estimates?
  13. 7833
    “…Exploiting the complementary advantages of two insect models (Drosophila melanogaster and Manduca sexta), we have investigated the regulation of APPL trafficking and processing with respect to different aspects of neuronal development. …”
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    Amyloid Precursor Proteins Are Dynamically Trafficked and Processed during Neuronal Development
  14. 7834
    “…This is illustrated by the fact that the model was also able to identify another new LPMO family in Drosophila melanogaster. Furthermore, the Hidden Markov model was used to verify the more distant blast hits from the new fungal family of LPMOs, which belong to the Bivalves, Stony corals and Sea anemones. …”
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    The discovery of novel LPMO families with a new Hidden Markov model
  15. 7835
    “…BACKGROUND: The identification of a DNA variant in pyridoxal kinase (Pdxk) associated with increased risk to Parkinson disease (PD) gene led us to study the inhibition of this gene in the Dopa decarboxylase (Ddc)-expressing neurons of the well-studied model organism Drosophila melanogaster. The multitude of biological functions attributable to the vitamers catalysed by this kinase reveal an overabundance of possible links to PD, that include dopamine synthesis, antioxidant activity and mitochondrial function. …”
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    A loss of Pdxk model of Parkinson disease in Drosophila can be suppressed by Buffy
  16. 7836
    “…To that end, we have previously reported the expression of a novel protein vaccine for malaria using the ExpreS(2)Drosophila melanogaster Schneider 2 stable cell line system, however, a very low overall process yield (typically <5% recovery of hexa-histidine-tagged protein) meant the initial purification strategy was not suitable for scale-up and clinical biomanufacture of such a vaccine. …”
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    Accelerating the clinical development of protein-based vaccines for malaria by efficient purification using a four amino acid C-terminal ‘C-tag’
  17. 7837
    “…Evolutionary comparisons revealed the existence of a single FAM20 gene in the simple vertebrate Ciona intestinalis and the invertebrate worm Caenorhabditis elegans and two genes in two insect species, Drosophila melanogaster and Anopheles gambiae. Six FAM20 family members were identified in the genome of the pufferfish, Fugu rubripes and five members in the zebrafish, Danio rerio. …”
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    FAM20: an evolutionarily conserved family of secreted proteins expressed in hematopoietic cells
  18. 7838
    por Saha, Surya, Hosmani, Prashant S, Villalobos-Ayala, Krystal, Miller, Sherry, Shippy, Teresa, Flores, Mirella, Rosendale, Andrew, Cordola, Chris, Bell, Tracey, Mann, Hannah, DeAvila, Gabe, DeAvila, Daniel, Moore, Zachary, Buller, Kyle, Ciolkevich, Kathryn, Nandyal, Samantha, Mahoney, Robert, Van Voorhis, Joshua, Dunlevy, Megan, Farrow, David, Hunter, David, Morgan, Taylar, Shore, Kayla, Guzman, Victoria, Izsak, Allison, Dixon, Danielle E, Cridge, Andrew, Cano, Liliana, Cao, Xiaolong, Jiang, Haobo, Leng, Nan, Johnson, Shannon, Cantarel, Brandi L, Richards, Stephen, English, Adam, Shatters, Robert G, Childers, Chris, Chen, Mei-Ju, Hunter, Wayne, Cilia, Michelle, Mueller, Lukas A, Munoz-Torres, Monica, Nelson, David, Poelchau, Monica F, Benoit, Joshua B, Wiersma-Koch, Helen, D’Elia, Tom, Brown, Susan J
    Publicado 2017
    “…However, knowledge transfer from well-curated reference genomes such as that of Drosophila melanogaster to newly sequenced ones is challenging due to the complexity and diversity of insect genomes. …”
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    Improved annotation of the insect vector of citrus greening disease: biocuration by a diverse genomics community
  19. 7839
    “…The transposable elements of the Tc1/mariner superfamily are often associated with hotspots for homologous recombination involved in human genetic disorders, such as Williams Beuren Syndromes (WBS) with LIM-kinase 1-dependent cognitive defects. The Drosophila melanogaster mutant agn(ts3) has unusual architecture of the agnostic locus harboring LIMK1: it is a hotspot of chromosome breaks, ectopic contacts, underreplication, and recombination. …”
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    Drosophila Model for the Analysis of Genesis of LIM-kinase 1-Dependent Williams-Beuren Syndrome Cognitive Phenotypes: INDELs, Transposable Elements of the Tc1/Mariner Superfamily and MicroRNAs
  20. 7840
    “…Discrete IHC staining in Drosophila melanogaster embryo brain was seen in glia and in neuroendocrine cells, with staining likely in the corpus cardiacum. …”
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    Mysterious inhibitory cell regulator investigated and found likely to be secretogranin II related
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