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121“…Using systemic bacterial infection in Drosophila melanogaster, we characterize chronic infection by three bacterial species from different genera - Providencia rettgeri, Serratia marcescens, and Enterococcus faecalis–following inoculation with a range of doses. …”
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122por Mahneva, Olena, Risley, Monica G., John, Ciny, Milton, Sarah L., Dawson-Scully, Ken, Ja, William W.“…While PAD homologs have been discovered in vertebrates—as well as in protozoa, fungi, and bacteria—none have been identified in Drosophila melanogaster, a simple and widely used animal model for human diseases. …”
Publicado 2020
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123“…We provide a point of view from which we discern that the underlying mechanism of activity-dependent plasticity may be common throughout the nervous systems in Drosophila melanogaster.…”
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125por Pegoraro, Mirko, Flavell, Laura M. M., Menegazzi, Pamela, Colombi, Perrine, Dao, Pauline, Helfrich-Förster, Charlotte, Tauber, Eran“…Under laboratory conditions, Drosophila melanogaster is crepuscular, showing a bi-modal activity profile. …”
Publicado 2020
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126por Sampson, Maureen M., Myers Gschweng, Katherine M., Hardcastle, Ben J., Bonanno, Shivan L., Sizemore, Tyler R., Arnold, Rebecca C., Gao, Fuying, Dacks, Andrew M., Frye, Mark A., Krantz, David E.“…Serotonergic neurons broadly innervate the optic ganglia of Drosophila melanogaster, a widely used model for studying vision. …”
Publicado 2020
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128por Layalle, Sophie, They, Laetitia, Ourghani, Sarah, Raoul, Cédric, Soustelle, Laurent“…In the last few decades, Drosophila melanogaster emerged as a versatile model for studying neurodegenerative diseases, including ALS. …”
Publicado 2021
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129por Jain, Kalpana, Lavista-Llanos, Sofia, Grabe, Veit, Hansson, Bill S., Wicher, Dieter“…A highly conserved calmodulin (CaM) binding site (CBS) (336)SAIKYWVER(344) within the second intracellular loop of Drosophila melanogaster Orco constitutes a target for regulating OR performance. …”
Publicado 2021
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131por Li, Jinzhi, Mahoney, Brennan Dale, Jacob, Miles Solomon, Cécile Caron, Sophie Jeanne“…The patterns of neuronal connectivity underlying multisensory integration, a fundamental property of many brains, remain poorly characterized. The Drosophila melanogaster mushroom body—an associative center—is an ideal system to investigate how different sensory channels converge in higher order brain centers. …”
Publicado 2020
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132“…We exposed fruit flies, Drosophila melanogaster, to either Roundup(®) Ready to Use, containing pelargonic acid and glyphosate, or Roundup(®) Super Concentrate, that includes glyphosate and POEA, at sublethal concentrations. …”
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133“…To provide insight on this issue, we sought to determine the extent to which genetic variation might play a role in one type of reproductive cost—survival—using Drosophila melanogaster. We found, surprisingly, no costs of reproduction nor sex differences in longevity across all 15 genetic backgrounds in two cohorts. …”
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134“…In addition, the development of high-throughput behavioral paradigms, where multiple isogenic animals can be analyzed in various environmental conditions, has again facilitated the study of the influence of genetic and environmental variations in animal personality. Mainly, Drosophila melanogaster has been the focus of a great effort to understand how inter-individual behavioral differences emerge. …”
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135“…We recently proposed that all acids are aversive at high concentrations, a response that is mediated by low pH as well as specific anions in Drosophila melanogaster. Particularly, some carboxylic acids such as glycolic acid, citric acid, and lactic acid are highly attractive to Drosophila compared with acetic acid. …”
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136por Taylor, Jackson R., Wood, Jason G., Mizerak, Evan, Hinthorn, Samuel, Liu, Julianna, Finn, Matthew, Gordon, Sarah, Zingas, Louis, Chang, Chengyi, Klein, Mark A., Denu, John M., Gorbunova, Vera, Seluanov, Andrei, Boeke, Jef D., Sedivy, John M., Helfand, Stephen L.“…Overexpressing Sirt6 extends lifespan in mice, but the underlying cellular mechanisms are unclear. Drosophila melanogaster are an excellent model to study genetic regulation of lifespan; however, despite extensive study in mammals, very little is known about Sirt6 function in flies. …”
Publicado 2022
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137por Zhao, Xiaqing, Golic, Forrest T., Harrison, Benjamin R., Manoj, Meghna, Hoffman, Elise V., Simon, Neta, Johnson, Richard, MacCoss, Michael J., McIntyre, Lauren M., Promislow, Daniel E. L.Enlace del recurso
Publicado 2022
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138“…The foraging gene in Drosophila melanogaster, which encodes a cGMP-dependent protein kinase, is a highly conserved, complex gene with multiple pleiotropic behavioral and physiological functions in both the larval and adult fly. …”
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140por Havula, E., Ghazanfar, S., Lamichane, N., Francis, D., Hasygar, K., Liu, Y., Alton, L. A., Johnstone, J., Needham, E. J., Pulpitel, T., Clark, T., Niranjan, H. N., Shang, V., Tong, V., Jiwnani, N., Audia, G., Alves, A. N., Sylow, L., Mirth, C., Neely, G. G., Yang, J., Hietakangas, V., Simpson, S. J., Senior, A. M.“…Here we explore the variation in macronutrient tolerance in Drosophila melanogaster using the Drosophila genetic reference panel, a collection of ~200 strains derived from a single natural population. …”
Publicado 2022
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