Materias dentro de su búsqueda.
Materias dentro de su búsqueda.
Películas cinematográficas
2
Cuartetos de cuerda
1
Cuartetos de cuerda, Arreglos
1
Documentary films
1
Etnología
1
In motion pictures
1
Metodología
1
Motion pictures, French
1
Música de cámara
1
Música electrónica
1
Música instrumental
1
Paternidad literaria
1
Videocassettes
1
Violin and piano music
1
Violin and piano music, Arranged
1
-
321por Bomberger, Jennifer M., Ye, Siying, MacEachran, Daniel P., Koeppen, Katja, Barnaby, Roxanna L., O'Toole, George A., Stanton, Bruce A.“…Cif redirected endocytosed CFTR from recycling endosomes to lysosomes by stabilizing an inhibitory effect of G3BP1 on the deubiquitinating enzyme (DUB), USP10, thereby reducing USP10-mediated deubiquitination of CFTR and increasing the degradation of CFTR in lysosomes. …”
Publicado 2011
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
322por Flierman, Dennis, van der Heden van Noort, Gerbrand J., Ekkebus, Reggy, Geurink, Paul P., Mevissen, Tycho E.T., Hospenthal, Manuela K., Komander, David, Ovaa, Huib“…Most tools for monitoring DUB specificity target binding pockets on opposing sides of the active site; however, some DUBs contain additional pockets. …”
Publicado 2016
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
323por Licchesi, Julien D.F., Mieszczanek, Juliusz, Mevissen, Tycho E.T., Rutherford, Trevor J., Akutsu, Masato, Virdee, Satpal, Oualid, Farid El, Chin, Jason W., Ovaa, Huib, Bienz, Mariann, Komander, David“…We here reveal how the human Ovarian Tumor (OTU) domain deubiquitinase (DUB) TRABID specifically hydrolyzes both Lys29- and Lys33-linked diubiquitin (diUb). …”
Publicado 2011
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
324“…Although there are far fewer DUBs than ubiquitin ligases encoded by the human genome, it is becoming clear that DUBs have very specific physiological functions, suggesting that DUB activity is tightly regulated in vivo. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
325por Kemp, Mark“…Inhibitors of two viral DUBs are also described since these proteases share structural similarity with one of the human DUB sub-families. …”
Publicado 2016
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
326por Krabill, Aaron D., Chen, Hao, Hussain, Sajjad, Hewitt, Chad S., Imhoff, Ryan D., Muli, Christine S., Das, Chittaranjan, Galardy, Paul J., Wendt, Michael K., Flaherty, Daniel P.“…The deubiquitinating enzyme (DUB) UCHL1 is implicated in various disease states including neurodegenerative disease and cancer. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
327por Priem, Dario, Devos, Michael, Druwé, Sarah, Martens, Arne, Slowicka, Karolina, Ting, Adrian T., Pasparakis, Manolis, Declercq, Wim, Vandenabeele, Peter, van Loo, Geert, Bertrand, Mathieu J. M.“…We demonstrate that Complex I-recruited A20 protects cells from apoptosis by stabilizing the linear (M1) ubiquitin network associated to Complex I, a process independent of its E3 ubiquitin ligase and deubiquitylase (DUB) activities and which is counteracted by the DUB CYLD, both in vitro and in vivo. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
328por Wilde, Mary-Louise, Ruparel, Ushma, Klemm, Theresa, Lee, V Vern, Calleja, Dale J, Komander, David, Tonkin, Christopher J“…This study presents comprehensive characterisation of Toxoplasma OTU DUBs. AlphaFold-guided structural analysis not only confirmed functional orthologues found across eukaryotes, but also identified apicomplexan-specific enzymes, subsequently enabling discovery of a cryptic OTU DUB in Plasmodium species. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
329“…In this study, we conducted binding assays using a human deubiquitinase (DUB) library and identified USP39 as a novel ETS2-binding DUB. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
330por Muneyyirci-Delale, Ozgul, Gupta, Anuja, Abraham, Cynthia, Chandrareddy, Ashadeep, Bowers, Charles H, Cutler, Jed B“…OBJECTIVE: To manage patients with dysfunctional uterine bleeding (DUB) according to endometrial thickness. METHODS: A retrospective chart review of 49 patients who reported 8 or more days of bleeding was performed. …”
Publicado 2010
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
331por Liu, Yanfen, Soetandyo, Nia, Lee, Jin-gu, Liu, Liping, Xu, Yue, Clemons, William M, Ye, Yihong“…A surprising paradox emerging from recent studies is that ubiquitin ligases (E3s) and deubiquitinases (DUBs), enzymes with opposing activities, can both promote ERAD. …”
Publicado 2014
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
332“…Our analysis has revealed examples of DUB gene subfunctionalization, neofunctionalization, and nonfunctionalization.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
333por Weber, Aurelia, Elliott, Paul R., Pinto-Fernandez, Adan, Bonham, Sarah, Kessler, Benedikt M., Komander, David, El Oualid, Farid, Krappmann, Daniel“…The methionine 1 (M1)-specific deubiquitinase (DUB) OTULIN acts as a negative regulator of nuclear factor κB signaling and immune homeostasis. …”
Publicado 2017
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
334“…In order to adequately study ubiquitin signaling and particularly deubiquitination, a number of ubiquitin activity-based probes (ABPs) were developed and utilized in understanding the deubiquitinase (DUBs) function. Here, we focus on the current state of the DUB ABP development and their application in understanding DUB function and specificity for polyubiquitin chains and ubiquitinated proteins.…”
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
335por Luo, Zhiyuan, Mu, Lili, Zheng, Yue, Shen, Wenchen, Li, Jiali, Xu, Lichao, Zhong, Bo, Liu, Ying, Zhou, Yan“…Intriguingly, BAP1 stabilizes N1ICD independent of its DUB activity but relying on the BRCA1-inhibiting function. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
336por van den Berk, Paul, Lancini, Cesare, Company, Carlos, Serresi, Michela, Sanchez-Bailon, Maria Pilar, Hulsman, Danielle, Pritchard, Colin, Song, Ji-Ying, Schmitt, Matthias Jürgen, Tanger, Ellen, Popp, Oliver, Mertins, Philipp, Huijbers, Ivo J., Jacobs, Heinz, van Lohuizen, Maarten, Gargiulo, Gaetano, Citterio, Elisabetta“…Altering ubiquitination by disruption of deubiquitinating enzymes (DUBs) affects hematopoietic stem cell (HSC) maintenance. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
337“…In this study, we identified differentially expressed E3s/DUB-related genes associated with the prognosis of lung adenocarcinoma and then constructed an E3s/DUB enzyme signature prediction model for the training group and validated its accuracy for prognosis prediction in the validation group. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
338por Qian, Meijia, Yan, Fangjie, Wang, Weihua, Du, Jiamin, Yuan, Tao, Wu, Ruilin, Zhao, Chenxi, Wang, Jiao, Lu, Jiabin, Zhang, Bo, Lin, Nengming, Dong, Xin, Dai, Xiaoyang, Dong, Xiaowu, Yang, Bo, Zhu, Hong, He, Qiaojun“…However, the underpinning mechanism remains poorly understood. Deubiquitinase (DUB) is regarded as a main orchestrator in maintaining protein homeostasis. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
339por Bascom, Carlisle, Prigge, Michael J., Szutu, Whitnie, Bantle, Alexis, Irmak, Sophie, Tu, Daniella, Estelle, Mark“…Additionally, leafy gametophore development in Δarfd(dub) lines lags behind wild type. We present evidence that ARFd1 interacts with activating ARFs via their PB1 domains, but not with repressing ARFs. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
340“…Because these DUBs are homologous to two members of a group of DUBs that act in fission yeast polarity, we tested additional members of that family and found that another C. elegans DUB gene, usp-46, also contributes to polarity. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto