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Mostrando 941 - 960 Resultados de 1,929 Para Buscar '"Dub"', tiempo de consulta: 0.15s Limitar resultados
  1. 941
    “…Accordingly, we constructed the on-line prediction tool dubbed DeepKhib for easily identifying K(hib) sites, which includes both species-specific and general models. …”
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    DeepKhib: A Deep-Learning Framework for Lysine 2-Hydroxyisobutyrylation Sites Prediction
  2. 942
    “…Thus, DUBs can be considered potential therapeutic targets for many cancers. …”
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    Deubiquitinase USP18 promotes the progression of pancreatic cancer via enhancing the Notch1-c-Myc axis
  3. 943
    “…Ubiquitination is an important post-translational modification that can be reversed by a family of enzymes called deubiquitinating enzymes (DUBs). Ubiquitin-specific protease 28 (USP28), a member of the DUBs family, functions as a potential tumour promoter in various cancers. …”
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    USP28 facilitates pancreatic cancer progression through activation of Wnt/β-catenin pathway via stabilising FOXM1
  4. 944
    “…PfUCHL3, a member of the ubiquitin C-terminal hydrolase (UCH) family of deubiquitinases (DUBs) is cardinal for parasite survival and emerges as a promising therapeutic target. …”
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    Repurposing the Pathogen Box compounds for identification of potent anti-malarials against blood stages of Plasmodium falciparum with PfUCHL3 inhibitory activity
  5. 945
    “…As significant posttranslational modifications, ubiquitination and deubiquitination, whose balance is modulated by ubiquitin-conjugating enzymes and deubiquitinating enzymes (DUBs), can regulate many biological processes, such as controlling cell cycle progression, signal transduction and transcriptional regulation. …”
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    Ubiquitin-specific protease 28: the decipherment of its dual roles in cancer development
  6. 946
    por Benveniste, Helene
    Publicado 2018
    “…A few years ago, a team of researchers—with the help of our author—finally found the answer. This discovery—dubbed the glymphatic system— will help us understand how toxic waste accumulates in devastating disorders such as Alzheimer’s disease and point to possible strategies to prevent it.…”
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    The Brain’s Waste-Removal System
  7. 947
    “…On June 8-10 of this year, we hosted a new symposium, dubbed the 1(st) International Symposium on Stress-Associated RNA Granules in Human Disease and Viral Infection. …”
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    1(st) International Symposium on Stress-Associated RNA Granules in Human Disease and Viral Infection
  8. 948
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    Enhancement of Intracellular Calcium Ion Mobilization by Moderately but Not Highly Positive Material Surface Charges
  9. 949
    “…We present predictions for double-quarkonium production in the kinematical region relevant for the proposed fixed-target experiment using the LHC beams (dubbed as AFTER@LHC). These include all spin-triplet S -wave charmonium and bottomonium pairs, i.e. …”
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    Double-quarkonium production at a fixed-target experiment at the LHC (AFTER@LHC)
  10. 950
    “…We have solved the Balistky-Kovchegov evolution equation including the impact-parameter dependence and obtained solutions which are not spoiled by theemergence of non-perturbative effects, dubbed Coulomb tails. This has beenachieved due to the fact that using the collinearly-improved kernel to the BKequation suppresses heavily the part of the phase-space of the equation fromwhich the Coulomb tails originate. …”
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    Impact parameter dependence of the collinearly improved Balitsky-Kovchegov evolution equation
  11. 951
    “…To our knowledge, a single case of an isolated lower epididymal pole with a normal vas deferens, dubbed “Epididymal Polar Dissociation”, has been reported in the literature. …”
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    Epididymal polar dissociation: A rare entity
  12. 952
    “…Here, utilizing enzymatic incorporation of fluorophore-conjugated sialic acids, dubbed as direct fluorescent glycan labeling, we report the labeling and detection of N- and O-glycans on glycoproteins. …”
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    Direct fluorescent glycan labeling with recombinant sialyltransferases
  13. 953
    por Jhaveri, Ravi
    Publicado 2020
    “…Although the recommendation is dubbed “universal,” this commentary reviews the details of the recommendations and discusses the high-risk populations not entirely captured with these changes.…”
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    Screening for Hepatitis C Virus: How Universal Is Universal?
  14. 954
    por Cusumano, Stefano, Rudnicki, Łukasz
    Publicado 2021
    “…In this context, in Entropy 2019, 21, 705, a formalism aiming at describing macroscopic quantum fields, dubbed Reduced State of the Field (RSF), was envisaged. …”
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    Thermodynamics of Reduced State of the Field
  15. 955
    “…We introduce two distance-weighted graph network architectures, dubbed GarNet and GravNet layers, and apply them to a typical particle reconstruction task. …”
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    Learning representations of irregular particle-detector geometry with distance-weighted graph networks
  16. 956
    “…Deubiquitinases (DUBs) play a critical role in ubiquitin-directed signaling by catalytically removing the ubiquitin from substrate proteins. …”
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    The Regulations of Deubiquitinase USP15 and Its Pathophysiological Mechanisms in Diseases
  17. 957
    “…The ubiquitin-specific protease (UBP) family is the largest group of deubiquitinases (DUBs), which perform extensive and significant roles in eukaryotic organisms. …”
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    Genome-wide identification and characterization of UBP gene family in wheat (Triticum aestivum L.)
  18. 958
    “…While the role of E3 ligase MDM2 in p53 ubiquitination is well-accepted, little is known about the involvement of deubiquitinases (DUBs). Herein, we found that the expression of YOD1, among several DUBs, is substantially reduced in blood cells from AML patients. …”
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    miR-221/222 induce instability of p53 By downregulating deubiquitinase YOD1 in acute myeloid leukemia
  19. 959
    por Durcan, Thomas M., Fon, Edward A.
    Publicado 2015
    “…Moreover, these modifications are reversible and can be disassembled by deubiquitinating enzymes (DUBs), including Ub-specific protease 8 (USP8), USP15, and USP30. …”
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    The three ‘P’s of mitophagy: PARKIN, PINK1, and post-translational modifications
  20. 960
    “…Both DUBs reside in the 19 S proteasome cap and their inhibition by VLX1570 results in rapid and tumor-specific apoptosis in bortezomib- or ibrutinib-resistant WM cells. …”
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    Coinhibition of the deubiquitinating enzymes, USP14 and UCHL5, with VLX1570 is lethal to ibrutinib- or bortezomib-resistant Waldenstrom macroglobulinemia tumor cells
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