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  1. 1181
    “…A method for the assignment of configuration of such compounds, of related α-trifluoromethylcyclohexylamines and of quaternary trifluoromethyl-substituted carbons is described based on the determination of the (3)J(CH) coupling constant between the fluorine-decoupled (13)CF(3) resonance and the vicinal hydrogens. This method is dubbed fluorine-decoupled carbon spectroscopy and abbreviated FDCS. …”
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    Fluorine-Decoupled Carbon Spectroscopy for the Determination of Configuration at Fully Substituted, Trifluoromethyl- and Perfluoroalkyl-Bearing Carbons: Comparison with (19)F–(1)H Heteronuclear Overhauser Effect Spectroscopy
  2. 1182
    “…Cardiac cells marked by c-Kit or Kit, dubbed cardiac stem cells (CSCs), are in clinical trials to investigate their ability to stimulate cardiac regeneration and repair. …”
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    Genetic lineage tracing identifies in situ Kit-expressing cardiomyocytes
  3. 1183
    “…Iterative cycles of rational inhibitor design and biophysical characterization led to the discovery of the triazolopthalazine‐based L‐45 (dubbed L‐Moses) as the first potent, selective, and cell‐active PCAF bromodomain (Brd) inhibitor. …”
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    Discovery of a PCAF Bromodomain Chemical Probe
  4. 1184
    “…However, the involvement of deubiquitylating enzymes (DUBs) targeting ubiquitylated histone H3 in the maintenance of DNA methylation is largely unknown. …”
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    Usp7-dependent histone H3 deubiquitylation regulates maintenance of DNA methylation
  5. 1185
    “…Here, we present a novel strategy for sequencing library preparation, dubbed ConcatSeq, which increases the throughput of SMS platforms by generating long concatenated templates from pools of short DNA molecules. …”
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    ConcatSeq: A method for increasing throughput of single molecule sequencing by concatenating short DNA fragments
  6. 1186
    “…In the last years, it is becoming clear that memory is not solely a feature of adaptive immunity, as it has been observed that also innate immune cells are provided with a sort of memory, dubbed “trained immunity.” In this review, we discuss the main characteristics of trained immunity as a possible contributor to inflammaging within the perspective of immunobiography, with particular attention to the phenotypic changes of the cell populations known to be involved in trained immunity. …”
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    Immunobiography and the Heterogeneity of Immune Responses in the Elderly: A Focus on Inflammaging and Trained Immunity
  7. 1187
    “…Recent evidence shows that fractured bones of neonatal mice undergo spontaneous realignment, dubbed “natural reduction.” Here, we show that natural reduction is regulated by the proprioceptive system and improves with age. …”
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    The Proprioceptive System Regulates Morphologic Restoration of Fractured Bones
  8. 1188
    “…Here we employ the variational approach for Markov processes (VAMP) to develop a deep learning framework for molecular kinetics using neural networks, dubbed VAMPnets. A VAMPnet encodes the entire mapping from molecular coordinates to Markov states, thus combining the whole data processing pipeline in a single end-to-end framework. …”
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    VAMPnets for deep learning of molecular kinetics
  9. 1189
    “…More exactly, we show that by overlaying a homogeneous artificial system (inspired by swarm intelligence) over a complex network (which is a heterogeneous system), and playing a game in the fused system, the changes in the homogeneous system will reflect perfectly the complex network properties. Our method, dubbed Game of Thieves (GOT), computes the importance of all network elements (both nodes and edges) in polylogarithmic time with respect to the total number of nodes. …”
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    Decentralized dynamic understanding of hidden relations in complex networks
  10. 1190
    “…A minimal model system for membrane fusion, comprising two complementary peptides dubbed “E” and “K” joined to a cholesterol anchor via a polyethyleneglycol spacer, has previously been developed in our group. …”
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    Peptide-Mediated Liposome Fusion: The Effect of Anchor Positioning
  11. 1191
    “…Topological magnons are emergent quantum spin excitations featured by magnon bands crossing linearly at the points dubbed nodes, analogous to fermions in topological electronic systems. …”
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    Discovery of coexisting Dirac and triply degenerate magnons in a three-dimensional antiferromagnet
  12. 1192
    “…Here we develop an approach, dubbed Controlled Hindrance of Adaptation of OrganismS or CHAOS, involving induction of epistasis between gene perturbations to deter adaption. …”
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    Multiplexed deactivated CRISPR-Cas9 gene expression perturbations deter bacterial adaptation by inducing negative epistasis
  13. 1193
    “…Here, our genome-wide transcriptome analysis of HERVs revealed that a primate long noncoding RNA, which we dubbed TROJAN, was highly expressed in human triple-negative breast cancer (TNBC). …”
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    The endogenous retrovirus-derived long noncoding RNA TROJAN promotes triple-negative breast cancer progression via ZMYND8 degradation
  14. 1194
    “…To identify driver TFs, we developed a new algorithm, dubbed Taiji, to assess the global influence of each TF and systematically uncovered TFs critical for lineage-specific and stage-dependent tissue specification. …”
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    Taiji: System-level identification of key transcription factors reveals transcriptional waves in mouse embryonic development
  15. 1195
    “…For this purpose, we introduce a new measure, dubbed spin-resolved localization length. We study uncorrelated disorder in the potential profile offered by the magnetic substrate or in the orientations of the magnetic moments concerning a given direction in space. …”
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    Spin-polarized localization in a magnetized chain
  16. 1196
    “…Black pepper (Piper nigrum), dubbed the ‘King of Spices’ and ‘Black Gold’, is one of the most widely used spices. …”
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    The chromosome-scale reference genome of black pepper provides insight into piperine biosynthesis
  17. 1197
    “…Here we show that thousands-to-millions of topological solitons, dubbed “skyrmions”, while each converting macroscopically-supplied electric energy, exhibit collective motions along spontaneously-chosen directions uncorrelated with the direction of electric field. …”
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    Schools of skyrmions with electrically tunable elastic interactions
  18. 1198
    “…From the primary screening of 27 various extracts of marine organisms collected in the Mediterranean Sea, an extract and subsequently a purified high molecular weight compound dubbed P3, were isolated from the marine sponge Crambe tailliezi and characterized as a selective inhibitor of PKs Aurora A and B. …”
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    Kinase-Based Screening of Marine Natural Extracts Leads to the Identification of a Cytotoxic High Molecular Weight Metabolite from the Mediterranean Sponge Crambe tailliezi
  19. 1199
    “…However, research on the role of deubiquitinating enzymes (DUBs) in cardiac function is limited. Here, we observed that the deubiquitinase ubiquitin C-terminal hydrolase 1 (UCHL1) was significantly up-regulated in agonist-stimulated primary cardiomyocytes and in hypertrophic and failing hearts. …”
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    The deubiquitinase UCHL1 regulates cardiac hypertrophy by stabilizing epidermal growth factor receptor
  20. 1200
    “…Quantitative proteomic analysis reveals the upregulation of E3 Ubiquitin ligase HUWE1 and DUBs like USP9X and UBP7 in both tumor and metastatic lesions, which is further confirmed in additional patients. …”
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    Proteogenomics analysis unveils a TFG-RET gene fusion and druggable targets in papillary thyroid carcinomas
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