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1201“…In this work, we present a local intrinsic rule that we developed, dubbed IP, inspired by the Infomax rule. Like Infomax, this rule works by controlling the gain and bias of a neuron to regulate its rate of fire. …”
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1202por Olsen, Reid H.J., DiBerto, Jeffrey F., English, Justin G., Glaudin, Alexis M., Krumm, Brian E., Slocum, Samuel T., Che, Tao, Gavin, Ariana C., McCorvy, John D., Roth, Bryan L., Strachan, Ryan T.“…To address this gap, we developed an open-source suite of 14 optimized Bioluminescence Resonance Energy Transfer (BRET) Gαβγ biosensors (dubbed TRUPATH) to interrogate the transducerome with single pathway resolution in cells. …”
Publicado 2020
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1203“…Recognition of these modifications by effector proteins, often dubbed histone “readers,” provides a link between the chromatin landscape and gene regulation. …”
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1204por Niño, Carlos A., Wollscheid, Nadine, Giangreco, Giovanni, Maspero, Elena, Polo, Simona“…Deubiquitinating enzymes (DUBs) may oppose the ubiquitylation process, antagonizing or even promoting receptor degradation. …”
Publicado 2020
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1205por Bagnolini, Greta, Milano, Domenico, Manerba, Marcella, Schipani, Fabrizio, Ortega, Jose Antonio, Gioia, Dario, Falchi, Federico, Balboni, Andrea, Farabegoli, Fulvia, De Franco, Francesca, Robertson, Janet, Pellicciari, Roberto, Pallavicini, Isabella, Peri, Sebastiano, Minucci, Saverio, Girotto, Stefania, Di Stefano, Giuseppina, Roberti, Marinella, Cavalli, Andrea“…Here, we exploit a new paradigm based on the possibility of triggering synthetic lethality using only small organic molecules (dubbed “fully small-molecule-induced synthetic lethality”). …”
Publicado 2020
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1206por Moore, Victoria Del Gaizo, Scheifele, Lisa Z., Chihade, Joseph W., Provost, Joseph J., Roecklein-Canfield, Jennifer A., Tsotakos, Nikolaos, Wolyniak, Michael J.“…The resulting interdisciplinary curriculum, dubbed “COVID-360,” enables instructors to select from a menu of curricular options that best fit their course content, desired activities, and mode of class delivery. …”
Publicado 2021
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1207“…This paper presents a miniature thermal sensor (dubbed TMOS) that is fabricated in advanced CMOS FABs, where the micromachined CMOS-SOI transistor, implemented with a 130-nm technology node, acts as a sensing element. …”
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1208“…Furthermore, STUbLs reside in the same vicinity as SUMO proteases and deubiquitinases (DUBs), providing spatiotemporal control of their targets. …”
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1209por Bello, Thomas, Chan, Marina, Golkowski, Martin, Xue, Andrew G., Khasnavis, Nithisha, Ceribelli, Michele, Ong, Shao-En, Thomas, Craig J., Gujral, Taranjit S.“…We develop a network propagation method that integrates kinase-inhibitor-focused functional screens with known protein-protein interactions (PPIs). This method, dubbed KiRNet, uses an a priori edge-weighting strategy based on node degree to establish a pipeline from a kinase inhibitor screen to the generation of a predictive PPI subnetwork. …”
Publicado 2021
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1210“…Primary care has been dubbed the “de facto” mental health system of the United States since the 1970s. …”
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1211por Tigard, Daniel W.“…Among the latter sort is what has been dubbed the ‘severance problem’—the idea that technologies sever our connection to the world, a connection which is necessary for us to flourish and live meaningful lives. …”
Publicado 2021
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1212Time-resolved in vivo ubiquitinome profiling by DIA-MS reveals USP7 targets on a proteome-wide scalepor Steger, Martin, Demichev, Vadim, Backman, Mattias, Ohmayer, Uli, Ihmor, Phillip, Müller, Stefan, Ralser, Markus, Daub, Henrik“…Our method enables rapid mode-of-action profiling of candidate drugs targeting DUBs or ubiquitin ligases at high precision and throughput.…”
Publicado 2021
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1213“…Key points from recent medical publications are paired with pre-existing artwork to provide visual reinforcement of the clinical pearl. Dubbed “Art and Aging”, the clinical pearl and artwork combination is posted on different social media platforms such as Instagram, Twitter and Facebook, thus allowing for an expansive audience. …”
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1214por Buytaert, Jan, Collins, Paula, Abed Abud, Adam, Allport, Phil, Pazos Álvarez, Antonio, Akiba, Kazuyoshi, de Aguiar Francisco, Oscar Augusto, Bay, Aurelio, Bernard, Florian, Baron, Sophie, Bertella, Claudia, Brunner, Josef X., Bowcock, Themis, Buytaert-De Jode, Martine, Byczynski, Wiktor, De Carvalho, Ricardo, Coco, Victor, Collins, Ruth, Dikic, Nikola, Dousse, Nicolas, Dowd, Bruce, Dreimanis, Kārlis, Dumps, Raphael, Durante, Paolo, Fadel, Walid, Farry, Stephen, Fernàndez Prieto, Antonio, Fernàndez Tèllez, Arturo, Flynn, Gordon, Franco Lima, Vinicius, Frei, Raymond, Gallas Torreira, Abraham, García Chàvez, Tonatiuh, Gazis, Evangelos, Guida, Roberto, Hennessy, Karol, Henriques, Andre, Hutchcroft, David, Ilic, Stefan, Ivanovs, Artūrs, Jevtic, Aleksandar, Jimenez Dominguez, Emigdio, Joram, Christian, Kapusniak, Kacper, Lemos Cid, Edgar, Lindner, Jana, Lindner, Rolf, Ivàn Martínez Hernàndez, M., Meboldt, Mirko, Milovanovic, Marko, Mico, Sylvain, Morant, Johan, Morel, Michel, Männel, Georg, Murray, Dónal, Nasteva, Irina, Neufeld, Niko, Neuhold, Igor, Pardo-Sobrino López, Francisco, Pèrez Trigo, Eliseo, Pichel Jallas, Gonzalo, Pilorz, Edyta, Piquilloud, Lise, Pons, Xavier, Reiner, David, Règules Medel, Hector David, Rodríguez Ramírez, Saul, Rodíguez Cahuantzi, Mario, Roosens, Carl, Rostalski, Philipp, Sanders, Freek, Saucet, Eric, Schmid Daners, Marianne, Schmidt, Burkhard, Schoettker, Patrick, Schwemmer, Rainer, Schindler, Heinrich, Sharma, Archana, Sivakumaran, Derick, Sigaud, Christophe, Spitas, Vasilios, Steffen, Nicola, Svihra, Peter, Tejeda Muñoz, Guillermo, Tachatos, Nikolaos, Tsolakis, Efstratios, van Leemput, Jan, Vignaux, Laurence, Vasey, Francois, Woonton, Hamish, Wyllie, Ken“…A high-quality, low-cost ventilator, dubbed HEV, has been developed by the particle physics community working together with biomedical engineers and physicians around the world. …”
Publicado 2022
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1215“…Phytochemicals can be dubbed as magic tramp cards that humans could exploit for lowering cancer-causing cholesterol. …”
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1216por Zhong, Ting, Lei, Kang, Lin, Xiaoxi, Xie, Zhiguo, Luo, Shuoming, Zhou, Zhiguang, Zhao, Bin, Li, Xia“…In this review, we summarize recent findings on the molecular mechanisms and cellular pathways that regulate thymocyte ubiquitination and discuss the roles of E3 ligases and deubiquitinating enzymes (DUBs) involved in these processes. Understanding how T cell development is regulated by ubiquitination and deubiquitination will not only enhance our understanding of cell fate determination via gene regulatory networks but also provide potential novel therapeutic strategies for treating autoimmune diseases and cancer.…”
Publicado 2022
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1217“…In recent years, the task of translating from one language to another has attracted wide attention from researchers due to numerous practical uses, ranging from the translation of various texts and speeches, including the so-called “machine” translation, to the dubbing of films and numerous other video materials. …”
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1218por Månsson, Erik P., Latini, Simone, Covito, Fabio, Wanie, Vincent, Galli, Mara, Perfetto, Enrico, Stefanucci, Gianluca, Hübener, Hannes, De Giovannini, Umberto, Castrovilli, Mattea C., Trabattoni, Andrea, Frassetto, Fabio, Poletto, Luca, Greenwood, Jason B., Légaré, François, Nisoli, Mauro, Rubio, Angel, Calegari, Francesca“…Sudden ionisation of a relatively large molecule can initiate a correlation-driven process dubbed charge migration, where the electron density distribution is expected to rapidly move along the molecular backbone. …”
Publicado 2021
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1219por Siegert, Frank“…Simulation programs for fully exclusive events, dubbed Monte-Carlo event generators, are improved in areas related to the perturbative as well as non-perturbative regions of strong interactions. …”
Publicado 2013
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1220por Volvovski, Ilya“…The year of 2012 was dubbed as the year of Big Data and Data Deluge, in 2013 petabyte scale is referenced matter­of­factly and exabyte size is now in the vocabulary of storage providers and large organization. …”
Publicado 2015
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