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1681por Oliveira, Getúlio P., Porto, William F., Palu, Cintia C., Pereira, Lydyane M., Petriz, Bernardo, Almeida, Jeeser A., Viana, Juliane, Filho, Nezio N. A., Franco, Octavio L., Pereira, Rinaldo W.“…Physical exercise stimulates organs, mainly the skeletal muscle, to release a broad range of molecules, recently dubbed exerkines. Among them, RNAs, such as miRNAs, piRNAs, and tRNAs loaded in extracellular vesicles (EVs) have the potential to play a significant role in the way muscle and other organs communicate to translate exercise into health. …”
Publicado 2018
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1682por Rendón-Gandarilla, Francisco Javier, Álvarez-Hernández, Víctor, Castañeda-Ortiz, Elizabeth J., Cárdenas-Hernández, Helios, Cárdenas-Guerra, Rosa Elena, Valdés, Jesús, Betanzos, Abigail, Chávez-Munguía, Bibiana, Lagunes-Guillen, Anel, Orozco, Esther, López-Canovas, Lilia, Azuara-Liceaga, Elisa“…Entamoeba histolytica, the parasite responsible of human amoebiasis, harbors three homologs of human TRFs, based on sequence similarities to their Myb DNA binding domain. These proteins were dubbed EhTRF-like I, II and III. In this work, we revealed that EhTRF-like I and II share similarity with human TRF1, while EhTRF-like III shares similarity with human TRF2 by in silico approach. …”
Publicado 2018
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1683por Wang, Xinbo, Xu, Yanhua, Li, Jingjing, Ren, Yongzhe, Wang, Zhiqiang, Xin, Zeyu, Lin, Tongbao“…Two DAPs (W5DYH0 and W5ERN8), dubbed TaDrSR1 and TaDrSR2, respectively, were selected for further functional analysis using VIGS. …”
Publicado 2018
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1684por Faccini de Lima, Camila, van der Elst, Louis A., Koraganji, Veda Narayana, Zheng, Mengxin, Gokce Kurtoglu, Merve, Gumennik, Alexander“…We develop a versatile hybrid-fabrication methodology that assembles in-fiber material architectures typical to integrated microelectronic devices and systems in silica, silicon, and high-temperature metals. This methodology, dubbed “VLSI for Fibers,” or “VLSI-Fi,” combines 3D printing of preforms, a thermal draw of fibers, and post-draw assembly of fiber-embedded integrated devices by means of material-selective spatially coherent capillary breakup of the fiber cores. …”
Publicado 2019
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1685por Lyamzaev, Konstantin G., Sumbatyan, Natalia V., Nesterenko, Alexey M., Kholina, Ekaterina G., Voskoboynikova, Natalia, Steinhoff, Heinz-Jürgen, Mulkidjanian, Armen Y., Chernyak, Boris V.“…We have synthesized a new mitochondria-targeted fluorescent probe sensitive to lipid peroxidation (dubbed MitoCLox), where the BODIPY fluorophore, carrying a diene-containing moiety (as in the C11-BODIPY (581/591) probe), is conjugated with a triphenylphosphonium cation (TPP(+)) via a long flexible linker that contains two amide bonds. …”
Publicado 2019
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1686por Salgado, Catarina, Roelse, Celine, Nell, Rogier, Gruis, Nelleke, van Doorn, Remco, van der Velden, Pieter“…Furthermore, two hotspot mutations in TERTp, dubbed C228T and C250T, have been revealed to facilitate binding of transcription factor ETS/TCF and subsequent TERT expression. …”
Publicado 2020
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1687por Ha, Jihoon, Kim, Minbeom, Seo, Dongyeob, Park, Jin Seok, Lee, Jaewon, Lee, Jinjoo, Park, Seok Hee“…Among the enzymes that mediate these post-translational modifications, little is known about the deubiquitinating enzymes (DUBs) that remove ubiquitin chains from p62, compared to the E3 ligases involved in p62 ubiquitination. …”
Publicado 2020
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1688por Zhao, Yixuan, Huang, Xin, Zhang, Zewei, Zhang, Yifan, Zhang, Guoyou, Zan, Tao, Li, Qingfeng“…Ubiquitin-specific peptidase 15 (USP15), an important member of the deubiquitinating enzymes (DUBs), removes ubiquitin chains from target proteins and maintains protein stability. …”
Publicado 2020
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1689por Bowleg, Lisa, Massie, Jenné S., Holt, Sidney L., Boone, Cheriko A., Mbaba, Mary, Stroman, Wayne A., Urada, Lianne, Raj, Anita“…Stroman, the lead peer counselor, on participants’ willingness to participate in MEN Count and disclose their challenges—we dubbed this the “Stroman Effect”; (b) the importance of Black men intervention deliverers with relatable life experiences; and (c) how contextual factors such as the HIV/AIDS epidemic, needs for housing and employment services and safe spaces to talk about challenges, and absentee fathers shaped participation. …”
Publicado 2020
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1690por Zink, Annika, Conrad, Josefin, Telugu, Narasimha Swami, Diecke, Sebastian, Heinz, Andreas, Wanker, Erich, Priller, Josef, Prigione, Alessandro“…Here, we developed a novel high-throughput (HT) assay to quantify mitochondrial and neuronal toxicity in human dopaminergic neuron-containing cultures (DNs) from induced pluripotent stem cells (iPSCs). The assay, dubbed mitochondrial neuronal health (MNH) assay, combines live-cell measurement of mitochondrial membrane potential (MMP) with quantification of neuronal branching complexity post-fixation. …”
Publicado 2020
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1691“…Research suggests that mental health and well-being improve as we age, and this trend is dubbed “the paradox of aging” (Charles & Carstensen, 2010). …”
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1692por Attia, Youssef A., El-Saadony, Mohamed T., Swelum, Ayman A., Qattan, Shaza Y.A., Al-qurashi, Adel D., Asiry, Khalid A., Shafi, Manal E., Elbestawy, Ahmed R., Gado, Ahmed R., Khafaga, Asmaa F., Hussein, Elsayed O.S., Ba-Awadh, Hani, Tiwari, Ruchi, Dhama, Kuldeep, Alhussaini, Bakr, Alyileili, Salem R., El-Tarabily, Khaled A., Abd El-Hack, Mohamed E.“…The World Health Organization (WHO) dubbed this contagious respiratory disease an “epidemic outbreak” in March 2020. …”
Publicado 2021
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1693por Dijksterhuis, Jan, Wyatt, Timon, Hanssen, Micha, Golovina, Elena, Hoekstra, Folkert, Lugones, Luis“…The gene encoding the protein, dubbed ICARUS, was studied in detail and was expressed under growth conditions that showed intense ascomata (fruit body) and ascospore formation. …”
Publicado 2021
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1694“…We propose a novel form of coupling, dubbed “power coupling,” between complex Hopf oscillators. …”
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1695“…The covalent and non-covalent docking plus subsequent MD refinement of known SARS-CoV inhibitors into DUBs and the SARS-CoV-2 PLpro point out a possible approach to target the PLpro cysteine protease from SARS-CoV-2. …”
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1696“…The disparity, originally dubbed “the great plate count anomaly” by Staley and Konopka, has become even more vexing given our increased understanding of the importance of microbiomes to a host and the role of microorganisms in the vital biogeochemical functions of our biosphere. …”
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1697“…In Drosophila female germline, many piRNA source loci dubbed “piRNA clusters” lack hallmarks of active genes and exploit an alternative path for transcription, which relies on the Rhino-Deadlock-Cutoff (RDC) complex. …”
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1698por Sanket, Shashwat, Vergin Raja Sarobin, M., Jani Anbarasi, L., Thakor, Jayraj, Singh, Urmila, Narayanan, Sathiya“…This paper proposes a convolutional neural network (CNN) based model for analysis/detection of COVID-19, dubbed as CovCNN, which uses the patient’s chest X-ray images for the diagnosis of COVID-19 with an aim to assist the medical practitioners to expedite the diagnostic process amongst high workload conditions. …”
Publicado 2021
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1699por González-Sanabria, Naileth, Echeverría, Felipe, Segura, Ignacio, Alvarado-Sánchez, Rosangelina, Latorre, Ramon“…This calcium- and voltage-activated potassium channel, dubbed BK for “Big K” due to its large ionic conductance between 130 and 300 pS in symmetric K(+). …”
Publicado 2021
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1700“…To address the problem of data imbalance, this paper proposes a method dubbed retinal fundus images generative adversarial networks (RF-GANs), which is based on generative adversarial network, to synthesize retinal fundus images. …”
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