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461por Sahajpal, Nikhil S., Mondal, Ashis K., Ananth, Sudha, Njau, Allan, Jones, Kimya, Ahluwalia, Pankaj, Oza, Eesha, Ross, Ted M., Kota, Vamsi, Kothandaraman, Arvind, Fulzele, Sadanand, Hegde, Madhuri, Chaubey, Alka, Rojiani, Amyn M., Kolhe, Ravindra“…This study evaluated clinical specimens (n = 1411), 1019 saliva and 392 nasopharyngeal swab (NPS), tested using two-assays: FDA-EUA approved SARS-CoV-2 assay that targets N and ORF1ab gene, and the PKamp-RT-PCR based assay that targets SARS-CoV-2, influenza viruses A and B. …”
Publicado 2022
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462“…Tocilizumab, an interleukin-6 (IL-6) blocker, received an emergency use authorization (EUA) by the Federal Drug Agency (FDA) in June 2021. …”
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463por Schäfer, Alexandra, Martinez, David R., Won, John J., Meganck, Rita M., Moreira, Fernando R., Brown, Ariane J., Gully, Kendra L., Zweigart, Mark R., Conrad, William S., May, Samantha R., Dong, Stephanie, Kalla, Rao, Chun, Kwon, Du Pont, Venice, Babusis, Darius, Tang, Jennifer, Murakami, Eisuke, Subramanian, Raju, Barrett, Kimberly T., Bleier, Blake J., Bannister, Roy, Feng, Joy Y., Bilello, John P., Cihlar, Tomas, Mackman, Richard L., Montgomery, Stephanie A., Baric, Ralph S., Sheahan, Timothy P.“…A direct comparison of GS-621763 with molnupiravir, an oral nucleoside analog antiviral which has recently received EUA approval, proved both drugs to be similarly efficacious in mice. …”
Publicado 2022
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464por Achenbach, Chad J., Caputo, Matthew, Hawkins, Claudia, Balmert, Lauren C., Qi, Chao, Odorisio, Joseph, Dembele, Etienne, Jackson, Alema, Abbas, Hiba, Frediani, Jennifer K., Levy, Joshua M., Rebolledo, Paulina A., Kempker, Russell R., Esper, Annette M., Lam, Wilbur A., Martin, Greg S., Murphy, Robert L.“…CONCLUSIONS: DASH POC SARS-CoV-2 PCR was accurate, easy to use, and provided fast results (approximately 15 minutes) in real-life clinical settings with an overall performance similar to an EUA-approved laboratory-based PCR.…”
Publicado 2022
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465por Guo, Yi, Cowman, Kelsie, Chang, Mei, Bao, Hongkai, Golia, Austin, Mcsweeney, Terrence, Bard, Linda, Simpson, Roxanne, Andrews, Erin, Pirofski, Liise-anne, Nori, Priya“…The median age was 39 years for unvaccinated patients, and 52 years for vaccinated patients (p < 0.0001). The median number of EUA criteria met was 1 for unvaccinated and 2 for vaccinated patients (p < 0.0001). …”
Publicado 2022
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4661402. Expand accessibility of monoclonal antibody in COVID-19 among different ethnicities and races.“…A total of 93 SARS-CoV-2-positive patients meeting EUA criteria for eligibility were infused with sotrovimab in different settings such as emergency department, outpatient setting including infusion clinics and cancer centers, home health as well as patients hospitalized due to reasons other than COVID-19 at RUSH medical center, Chicago. …”
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467por Woodard, LeChauncy, Gilbert, Lauren, King, Ben, Adepoju, Omolola E., Bruce, Marino A., McDougle, Leon, Moultry, Aisha Morris, Beech, Bettina M.“…METHODS: We conducted a cross-sectional, online survey of Black and Hispanic healthcare providers who were members of the National Medical Association (NMA), National Hispanic Medical Association (NHMA), and National Pharmaceutical Association (NPhA) between January 11 – March 3, 2021, shortly after emergency use authorization (EUA) for the Pfizer and Moderna COVID-19 vaccines. …”
Publicado 2023
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468por Gentry, Chris A., Nguyen, Phoi, Thind, Sharanjeet K., Kurdgelashvili, George, Williams, Riley J.“…OBJECTIVES: Molnupiravir and nirmatrelvir/ritonavir each became available in the United States (US) through the Food and Drug Administration (FDA) emergency use authorization (EUA) in December 2021 after their respective initial prospective randomized controlled trials demonstrated efficacy for patients with mild-to-moderate SARS-CoV-2 active infection considered to be at high risk for progression of disease and hospitalization. …”
Publicado 2023
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469por Chen, Benjamin, Haste, Nina, Binkin, Nancy, Law, Nancy, Horton, Lucy E., Yam, Nancy, Chen, Victor, Abeles, Shira“…BACKGROUND: Pre-exposure prophylaxis for COVID-19 with tixagevimab/cilgavimab (T/C) received Emergency Use Authorization (EUA) based on results of a clinical trial conducted prior to the emergence of the Omicron variant. …”
Publicado 2023
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470“…BACKGROUND: In December 2021, the FDA issued an emergency use authorization (EUA) for nirmatrelvir-ritonavir (Paxlovid). This was based on the randomized placebo-controlled trial data from the EPIC-HR study which showed that high-risk non-hospitalized patients given Paxlovid had an 88.9% reduction in the relative risk of progression to hospitalization or death by Day 28 in coronavirus disease 2019 (COVID-19). …”
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471por Skoczkowski, Tadeusz, Bielecki, Sławomir, Węglarz, Arkadiusz, Włodarczak, Magdalena, Gutowski, Piotr“…The impact of the increase of the European Emission Allowance (EUA) price on fossil fuel power sector has been modelled for different scenarios. …”
Publicado 2018
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472por Lista, Maria Jose, Matos, Pedro M., Maguire, Thomas J. A., Poulton, Kate, Ortiz-Zapater, Elena, Page, Robert, Sertkaya, Helin, Ortega-Prieto, Ana M., O’Byrne, Aoife M., Bouton, Clement, Dickenson, Ruth E, Ficarelli, Mattia, Jimenez-Guardeño, Jose M., Howard, Mark, Betancor, Gilberto, Galao, Rui Pedro, Pickering, Suzanne, Signell, Adrian W, Wilson, Harry, Cliff, Penelope, Ik, Mark Tan Kia, Patel, Amita, MacMahon, Eithne, Cunningham, Emma, Doores, Katie, Agromayor, Monica, Martin-Serrano, Juan, Perucha, Esperanza, Mischo, Hannah E., Shankar-Hari, Manu, Batra, Rahul, Edgeworth, Jonathan, Zuckerman, Mark, Malim, Michael H., Neil, Stuart, Martinez-Nunez, Rocio Teresa“…We used primer-probes that detect viral N (EUA CDC) and RdRP (PHE guidelines). All RNA extraction methods provided similar results. …”
Publicado 2021
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473por Renard, Nathalie, Daniel, Soizic, Cayet, Nadège, Pecquet, Matthieu, Raymond, Frédérique, Pons, Sylvie, Lupo, Julien, Tourneur, Carole, Pretis, Catherine, Gerez, Guillaume, Blasco, Patrick, Combe, Maxime, Canova, Imen, Lesénéchal, Mylène, Berthier, Franck“…We describe here the analytical and clinical performance of Vidas SARS-CoV-2 IgM and Vidas SARS-CoV-2 IgG, two CE-marked, emergency use authorization (EUA)-authorized, automated, qualitative assays for the detection of SARS-CoV-2-specific IgM and IgG, respectively. …”
Publicado 2021
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474por Ash, Jordan, Leavitt, Rachael, Dietrich, Tyson, Schritter, Sarah, Wells, James, Santarelli, Anthony, Ashurst, John“…INTRODUCTION: Monoclonal antibodies received an Emergency Use Authorization (EUA) from the U.S. Food & Drug Administration for the outpatient treatment of mild to moderate coronavirus disease 2019 (COVID-19). …”
Publicado 2021
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475por Lista, Maria Jose, Matos, Pedro M., Maguire, Thomas J. A., Poulton, Kate, Ortiz-Zapater, Elena, Page, Robert, Sertkaya, Helin, Ortega-Prieto, Ana M., Scourfield, Edward, O’Byrne, Aoife M., Bouton, Clement, Dickenson, Ruth E., Ficarelli, Mattia, Jimenez-Guardeño, Jose M., Howard, Mark, Betancor, Gilberto, Galao, Rui Pedro, Pickering, Suzanne, Signell, Adrian W., Wilson, Harry, Cliff, Penelope, Kia Ik, Mark Tan, Patel, Amita, MacMahon, Eithne, Cunningham, Emma, Doores, Katie, Agromayor, Monica, Martin-Serrano, Juan, Perucha, Esperanza, Mischo, Hannah E., Shankar-Hari, Manu, Batra, Rahul, Edgeworth, Jonathan, Zuckerman, Mark, Malim, Michael H., Neil, Stuart, Martinez-Nunez, Rocio Teresa“…We used primer-probes that detect viral N (EUA CDC) and RdRP. RNA extraction methods provided similar results, with Beckman performing better with our primer-probe combinations. …”
Publicado 2021
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476por Leavitt, Rachael, Ash, Jordan, Hasenbalg, Phillip, Santarelli, Anthony, Dietrich, Tyson, Schritter, Sarah, Wells, James, Dawson, Adam, Ashurst, John“…Introduction Although there were several proposed treatments for patients that were hospitalized with COVID-19, outpatient treatments for those with mild to moderate illness were limited prior to the emergency use authorization (EUA) of virus-neutralizing monoclonal antibodies. …”
Publicado 2021
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477por Mena Lora, Alfredo J, Echeverria, Stephanie L, Herald, Fischer, McSweeney, James, Gumasana, Harshil, Burgos, Rodrigo M, Borgetti, Scott“…In November 2020, several mAbs were issued an EUA by the FDA as single-dose intravenous (IV) infusions for treatment of mild to moderate COVID-19. mABs were allocated to local health facilities capable of administering infusions and managing side effects. …”
Publicado 2021
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478“…Eligibility to participate included recipients of vaccines who received Emergency Use Authorization (EUA) in India. Data were analyzed using SPSS version 20.00 (IBM Corporation, Armonk, NY, USA). …”
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479por Proia, Eleonora, Ragno, Alessio, Antonini, Lorenzo, Sabatino, Manuela, Mladenovič, Milan, Capobianco, Roberto, Ragno, Rino“…FDA emergency use authorization (EUA) for the oral treatment of mild-to-moderate COVID-19 infected patients. …”
Publicado 2022
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480“…Background: Remdesivir was granted EUA followed by full FDA approval for treatment of hospitalized COVID-19 patients on October 22, 2020, based on the results from the ACTT1 trial. …”
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