Functional Analysis Identifies Damaging CHEK2 Missense Variants Associated with Increased Cancer Risk

por Boonen, Rick A.C.M., Wiegant, Wouter W., Celosse, Nandi, Vroling, Bas, Heijl, Stephan, Kote-Jarai, Zsofia, Mijuskovic, Martina, Cristea, Simona, Solleveld-Westerink, Nienke, van Wezel, Tom, Beerenwinkel, Niko, Eeles, Rosalind, Devilee, Peter, Vreeswijk, Maaike P.G., Marra, Giancarlo, van Attikum, Haico
Publicado 2022

Comparative Analysis for Glycopatterns and Complex-Type N-Glycans of Glycoprotein in Sera from Chronic Hepatitis B- and C-Infected Patients

por Qin, Xinmin, Guo, Yonghong, Du, Haoqi, Zhong, Yaogang, Zhang, Jiaxu, Li, Xuetian, Yu, Hanjie, Zhang, Zhiwei, Jia, Zhansheng, Li, Zheng
Publicado 2017

Biochemical activity induced by a germline variation in KLK3 (PSA) associates with cellular function and clinical outcome in prostate cancer

por Srinivasan, Srilakshmi, Kryza, Thomas, Bock, Nathalie, Tse, Brian WC, Sokolowski, Kamil A., Panchadsaram, Janaththani, Moya, Leire, Stephens, Carson, Dong, Ying, Röhl, Joan, Alinezhad, Saeid, Vela, Ian, Perry-Keene, Joanna L., Buzacott, Katie, Gago-Dominguez, Manuela, Schleutker, Johanna, Maier, Christiane, Muir, Kenneth, Tangen, Catherine M., Gronberg, Henrik, Pashayan, Nora, Albanes, Demetrius, Wolk, Alicja, Stanford, Janet L., Berndt, Sonja I., Mucci, Lorelei A., Koutros, Stella, Cussenot, Olivier, Sorensen, Karina Dalsgaard, Grindedal, Eli Marie, Key, Timothy J., Haiman, Christopher A., Giles, Graham G., Vega, Ana, Wiklund, Fredrik, Neal, David E., Kogevinas, Manolis, Stampfer, Meir J., Nordestgaard, Børge G., Brenner, Hermann, Gamulin, Marija, Claessens, Frank, Melander, Olle, Dahlin, Anders, Stattin, Pär, Hallmans, Göran, Häggström, Christel, Johansson, Robert, Thysell, Elin, Rönn, Ann-Charlotte, Li, Weiqiang, Brown, Nigel, Dimeski, Goce, Shepherd, Benjamin, Dadaev, Tokhir, Brook, Mark N., Spurdle, Amanda B., Stenman, Ulf-Håkan, Koistinen, Hannu, Kote-Jarai, Zsofia, Klein, Robert J., Lilja, Hans, Ecker, Rupert C., Eeles, Rosalind, Clements, Judith, Batra, Jyotsna
Publicado 2023

CAG and GGC repeat polymorphisms in the androgen receptor gene and breast cancer susceptibility in BRCA1/2 carriers and non-carriers

por Kadouri, L, Easton, D F, Edwards, S, Hubert, A, Kote-Jarai, Z, Glaser, B, Durocher, F, Abeliovich, D, Peretz, T, Eeles, R A
Publicado 2001

Psychosocial impact of breast/ovarian (BRCA1/2) cancer-predictive genetic testing in a UK multi-centre clinical cohort

por Watson, M, Foster, C, Eeles, R, Eccles, D, Ashley, S, Davidson, R, Mackay, J, Morrison, P J, Hopwood, P, Evans, D G R
Publicado 2004

Glutathione-S-transferase M1, T1 and P1 polymorphisms, and breast cancer risk, in BRCA1/2 mutation carriers

por Kadouri, L, Kote-Jarai, Z, Hubert, A, Baras, M, Abeliovich, D, Hamburger, T, Peretz, T, Eeles, R A
Publicado 2008

Atlantic cod (Gadus morhua) hemoglobin genes: multiplicity and polymorphism

por Borza, Tudor, Stone, Cynthia, Gamperl, A Kurt, Bowman, Sharen
Publicado 2009

Evaluation of Association of HNF1B Variants with Diverse Cancers: Collaborative Analysis of Data from 19 Genome-Wide Association Studies

por Elliott, Katherine S., Zeggini, Eleftheria, McCarthy, Mark I., Gudmundsson, Julius, Sulem, Patrick, Stacey, Simon N., Thorlacius, Steinunn, Amundadottir, Laufey, Grönberg, Henrik, Xu, Jianfeng, Gaborieau, Valerie, Eeles, Rosalind A., Neal, David E., Donovan, Jenny L., Hamdy, Freddie C., Muir, Kenneth, Hwang, Shih-Jen, Spitz, Margaret R., Zanke, Brent, Carvajal-Carmona, Luis, Brown, Kevin M., Hayward, Nicholas K., Macgregor, Stuart, Tomlinson, Ian P. M., Lemire, Mathieu, Amos, Christopher I., Murabito, Joanne M., Isaacs, William B., Easton, Douglas F., Brennan, Paul, Barkardottir, Rosa B., Gudbjartsson, Daniel F., Rafnar, Thorunn, Hunter, David J., Chanock, Stephen J., Stefansson, Kari, Ioannidis, John P. A.
Publicado 2010

Effects of BRCA2 cis-regulation in normal breast and cancer risk amongst BRCA2 mutation carriers

por Maia, Ana-Teresa, Antoniou, Antonis C, O'Reilly, Martin, Samarajiwa, Shamith, Dunning, Mark, Kartsonaki, Christiana, Chin, Suet-Feung, Curtis, Christina N, McGuffog, Lesley, Domchek, Susan M, Easton, Douglas F, Peock, Susan, Frost, Debra, Evans, D Gareth, Eeles, Ros, Izatt, Louise, Adlard, Julian, Eccles, Diana, Sinilnikova, Olga M, Mazoyer, Sylvie, Stoppa-Lyonnet, Dominique, Gauthier-Villars, Marion, Faivre, Laurence, Venat-Bouvet, Laurence, Delnatte, Capucine, Nevanlinna, Heli, Couch, Fergus J, Godwin, Andrew K, Caligo, Maria Adelaide, Barkardottir, Rosa B, Chen, Xiaoqing, Beesley, Jonathan, Healey, Sue, Caldas, Carlos, Chenevix-Trench, Georgia, Ponder, Bruce AJ
Publicado 2012

Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression

por Kote-Jarai, Zsofia, Saunders, Edward J., Leongamornlert, Daniel A., Tymrakiewicz, Malgorzata, Dadaev, Tokhir, Jugurnauth-Little, Sarah, Ross-Adams, Helen, Al Olama, Ali Amin, Benlloch, Sara, Halim, Silvia, Russel, Roslin, Dunning, Alison M., Luccarini, Craig, Dennis, Joe, Neal, David E., Hamdy, Freddie C., Donovan, Jenny L., Muir, Ken, Giles, Graham G., Severi, Gianluca, Wiklund, Fredrik, Gronberg, Henrik, Haiman, Christopher A., Schumacher, Fredrick, Henderson, Brian E., Le Marchand, Loic, Lindstrom, Sara, Kraft, Peter, Hunter, David J., Gapstur, Susan, Chanock, Stephen, Berndt, Sonja I., Albanes, Demetrius, Andriole, Gerald, Schleutker, Johanna, Weischer, Maren, Canzian, Federico, Riboli, Elio, Key, Tim J., Travis, Ruth C., Campa, Daniele, Ingles, Sue A., John, Esther M., Hayes, Richard B., Pharoah, Paul, Khaw, Kay-Tee, Stanford, Janet L., Ostrander, Elaine A., Signorello, Lisa B., Thibodeau, Stephen N., Schaid, Dan, Maier, Christiane, Vogel, Walther, Kibel, Adam S., Cybulski, Cezary, Lubinski, Jan, Cannon-Albright, Lisa, Brenner, Hermann, Park, Jong Y., Kaneva, Radka, Batra, Jyotsna, Spurdle, Amanda, Clements, Judith A., Teixeira, Manuel R., Govindasami, Koveela, Guy, Michelle, Wilkinson, Rosemary A., Sawyer, Emma J., Morgan, Angela, Dicks, Ed, Baynes, Caroline, Conroy, Don, Bojesen, Stig E., Kaaks, Rudolf, Vincent, Daniel, Bacot, François, Tessier, Daniel C., Easton, Douglas F., Eeles, Rosalind A.
Publicado 2013

Fine-Mapping the HOXB Region Detects Common Variants Tagging a Rare Coding Allele: Evidence for Synthetic Association in Prostate Cancer

por Saunders, Edward J., Dadaev, Tokhir, Leongamornlert, Daniel A., Jugurnauth-Little, Sarah, Tymrakiewicz, Malgorzata, Wiklund, Fredrik, Al Olama, Ali Amin, Benlloch, Sara, Neal, David E., Hamdy, Freddie C., Donovan, Jenny L., Giles, Graham G., Severi, Gianluca, Gronberg, Henrik, Aly, Markus, Haiman, Christopher A., Schumacher, Fredrick, Henderson, Brian E., Lindstrom, Sara, Kraft, Peter, Hunter, David J., Gapstur, Susan, Chanock, Stephen, Berndt, Sonja I., Albanes, Demetrius, Andriole, Gerald, Schleutker, Johanna, Weischer, Maren, Nordestgaard, Børge G., Canzian, Federico, Campa, Daniele, Riboli, Elio, Key, Tim J., Travis, Ruth C., Ingles, Sue A., John, Esther M., Hayes, Richard B., Pharoah, Paul, Khaw, Kay-Tee, Stanford, Janet L., Ostrander, Elaine A., Signorello, Lisa B., Thibodeau, Stephen N., Schaid, Daniel, Maier, Christiane, Kibel, Adam S., Cybulski, Cezary, Cannon-Albright, Lisa, Brenner, Hermann, Park, Jong Y., Kaneva, Radka, Batra, Jyotsna, Clements, Judith A., Teixeira, Manuel R., Xu, Jianfeng, Mikropoulos, Christos, Goh, Chee, Govindasami, Koveela, Guy, Michelle, Wilkinson, Rosemary A., Sawyer, Emma J., Morgan, Angela, Easton, Douglas F., Muir, Ken, Eeles, Rosalind A., Kote-Jarai, Zsofia
Publicado 2014

Rapid and long-term effects of water deficit on gas exchange and hydraulic conductance of silver birch trees grown under varying atmospheric humidity

por Sellin, Arne, Niglas, Aigar, Õunapuu-Pikas, Eele, Kupper, Priit
Publicado 2014

Neurobehaviour between birth and 40 weeks’ gestation in infants born <30 weeks’ gestation and parental psychological wellbeing: predictors of brain development and child outcomes...

por Spittle, Alicia J, Thompson, Deanne K, Brown, Nisha C, Treyvaud, Karli, Cheong, Jeanie LY, Lee, Katherine J, Pace, Carmen C, Olsen, Joy, Allinson, Leesa G, Morgan, Angela T, Seal, Marc, Eeles, Abbey, Judd, Fiona, Doyle, Lex W, Anderson, Peter J
Publicado 2014

Heterogeneous Genetic Background of the Association of Pheochromocytoma/Paraganglioma and Pituitary Adenoma: Results From a Large Patient Cohort

por Dénes, Judit, Swords, Francesca, Rattenberry, Eleanor, Stals, Karen, Owens, Martina, Cranston, Treena, Xekouki, Paraskevi, Moran, Linda, Kumar, Ajith, Wassif, Christopher, Fersht, Naomi, Baldeweg, Stephanie E., Morris, Damian, Lightman, Stafford, Agha, Amar, Rees, Aled, Grieve, Joan, Powell, Michael, Boguszewski, Cesar Luiz, Dutta, Pinaki, Thakker, Rajesh V., Srirangalingam, Umasuthan, Thompson, Chris J., Druce, Maralyn, Higham, Claire, Davis, Julian, Eeles, Rosalind, Stevenson, Mark, O'Sullivan, Brendan, Taniere, Phillipe, Skordilis, Kassiani, Gabrovska, Plamena, Barlier, Anne, Webb, Susan M., Aulinas, Anna, Drake, William M., Bevan, John S., Preda, Cristina, Dalantaeva, Nadezhda, Ribeiro-Oliveira, Antônio, Garcia, Isabel Tena, Yordanova, Galina, Iotova, Violeta, Evanson, Jane, Grossman, Ashley B., Trouillas, Jacqueline, Ellard, Sian, Stratakis, Constantine A., Maher, Eamonn R., Roncaroli, Federico, Korbonits, Márta
Publicado 2015

Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study

por Zhang, Chenan, Doherty, Jennifer A., Burgess, Stephen, Hung, Rayjean J., Lindström, Sara, Kraft, Peter, Gong, Jian, Amos, Christopher I., Sellers, Thomas A., Monteiro, Alvaro N.A., Chenevix-Trench, Georgia, Bickeböller, Heike, Risch, Angela, Brennan, Paul, Mckay, James D., Houlston, Richard S., Landi, Maria Teresa, Timofeeva, Maria N., Wang, Yufei, Heinrich, Joachim, Kote-Jarai, Zsofia, Eeles, Rosalind A., Muir, Ken, Wiklund, Fredrik, Grönberg, Henrik, Berndt, Sonja I., Chanock, Stephen J., Schumacher, Fredrick, Haiman, Christopher A., Henderson, Brian E., Amin Al Olama, Ali, Andrulis, Irene L., Hopper, John L., Chang-Claude, Jenny, John, Esther M., Malone, Kathleen E., Gammon, Marilie D., Ursin, Giske, Whittemore, Alice S., Hunter, David J., Gruber, Stephen B., Knight, Julia A., Hou, Lifang, Le Marchand, Loic, Newcomb, Polly A., Hudson, Thomas J., Chan, Andrew T., Li, Li, Woods, Michael O., Ahsan, Habibul, Pierce, Brandon L.
Publicado 2015

Blood lipids and prostate cancer: a Mendelian randomization analysis

por Bull, Caroline J., Bonilla, Carolina, Holly, Jeff M. P., Perks, Claire M., Davies, Neil, Haycock, Philip, Yu, Oriana Hoi Yun, Richards, J. Brent, Eeles, Rosalind, Easton, Doug, Kote‐Jarai, Zsofia, Amin Al Olama, Ali, Benlloch, Sara, Muir, Kenneth, Giles, Graham G., MacInnis, Robert J., Wiklund, Fredrik, Gronberg, Henrik, Haiman, Christopher A., Schleutker, Johanna, Nordestgaard, Børge G., Travis, Ruth C., Neal, David, Pashayan, Nora, Khaw, Kay‐Tee, Stanford, Janet L., Blot, William J., Thibodeau, Stephen, Maier, Christiane, Kibel, Adam S., Cybulski, Cezary, Cannon‐Albright, Lisa, Brenner, Hermann, Park, Jong, Kaneva, Radka, Batra, Jyotsna, Teixeira, Manuel R., Micheal, Agnieszka, Pandha, Hardev, Smith, George Davey, Lewis, Sarah J., Martin, Richard M.
Publicado 2016

Polyunsaturated fatty acids and prostate cancer risk: a Mendelian randomisation analysis from the PRACTICAL consortium

por Khankari, Nikhil K, Murff, Harvey J, Zeng, Chenjie, Wen, Wanqing, Eeles, Rosalind A, Easton, Douglas F, Kote-Jarai, Zsofia, Al Olama, Ali Amin, Benlloch, Sara, Muir, Kenneth, Giles, Graham G, Wiklund, Fredrik, Gronberg, Henrik, Haiman, Christopher A, Schleutker, Johanna, Nordestgaard, Børge G, Travis, Ruth C, Donovan, Jenny L, Pashayan, Nora, Khaw, Kay-Tee, Stanford, Janet L, Blot, William J, Thibodeau, Stephen N, Maier, Christiane, Kibel, Adam S, Cybulski, Cezary, Cannon-Albright, Lisa, Brenner, Hermann, Park, Jong, Kaneva, Radka, Batra, Jyotsna, Teixeira, Manuel R, Pandha, Hardev, Zheng, Wei
Publicado 2016

Alcohol consumption and prostate cancer incidence and progression: A Mendelian randomisation study

por Brunner, Clair, Davies, Neil M., Martin, Richard M., Eeles, Rosalind, Easton, Doug, Kote‐Jarai, Zsofia, Al Olama, Ali Amin, Benlloch, Sara, Muir, Kenneth, Giles, Graham, Wiklund, Fredrik, Gronberg, Henrik, Haiman, Christopher A., Schleutker, Johanna, Nordestgaard, Børge G., Travis, Ruth C., Neal, David, Donovan, Jenny, Hamdy, Freddie C., Pashayan, Nora, Khaw, Kay‐Tee, Stanford, Janet L., Blot, William J., Thibodeau, Stephen, Maier, Christiane, Kibel, Adam S., Cybulski, Cezary, Cannon‐Albright, Lisa, Brenner, Hermann, Park, Jong, Kaneva, Radka, Batra, Jyotsna, Teixeira, Manuel R., Pandha, Hardev, Zuccolo, Luisa
Publicado 2016

Germline variants in IL4, MGMT and AKT1 are associated with prostate cancer-specific mortality: An analysis of 12,082 prostate cancer cases

por FitzGerald, L. M., Zhao, S., Leonardson, A., Geybels, M. S., Kolb, S., Lin, D. W., Wright, J. L., Eeles, R., Kote-Jarai, Z., Govindasami, K., Giles, G. G., Southey, M. C., Schleutker, J., Tammela, T. L., Sipeky, C., Penney, K. L., Stampfer, M. J., Gronberg, H., Wiklund, F., Stattin, P., Hugosson, J., Karyadi, D. M., Ostrander, E. A., Feng, Z., Stanford, J. L.
Publicado 2018

Germline DNA Repair Gene Mutations in Young-onset Prostate Cancer Cases in the UK: Evidence for a More Extensive Genetic Panel

por Leongamornlert, Daniel A., Saunders, Edward J., Wakerell, Sarah, Whitmore, Ian, Dadaev, Tokhir, Cieza-Borrella, Clara, Benafif, Sarah, Brook, Mark N., Donovan, Jenny L., Hamdy, Freddie C., Neal, David E., Muir, Kenneth, Govindasami, Koveela, Conti, David V., Kote-Jarai, Zsofia, Eeles, Rosalind A.
Publicado 2019